PARICALCITOL

(PAR i KAL si tol) Brand: Zemplar

What is the most significant information I must know about paricalcitol?

• Do not use this medicine if you have ever had an allergic reaction to vitamin D, or if you have tall levels of calcium or vitamin D in your blood.

• Till taking paricalcitol, speak your doctor if you have tall blood pressure, liver malady, or an electrolyte imbalance.

• Do not take another vitamin or mineral supplements unless your doctor has told you to.

• Avoid using calcium supplements or antacids without your doctor's advice. Use only the specific type of supplement or antacid your doctor recommends. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

• While using paricalcitol, you may need blood trials at your doctor's office. Visit your doctor regularly.

• Search abnormal medical attention if you think you have used too many of this medication. An overdose of vitamin D can reason serious or life-threatening side effects.

• Overdose symptoms may include headache, weakness, drowsiness, dry mouth, nausea, vomiting, constipation, muscle or bone pain, metallic taste in the mouth, weight loss, itchy skin, changes in heart course, loss of interest in sex, confusion, unusual thoughts or behavior, feeling unusually hot, severe pain in your upper stomach spreading to your back, or fainting.

• Paricalcitol is only part of a complete program of treatment that may also include a particular diet. It is very significant to follow the diet plan created for you by your doctor or nutrition counselor. You must become very familiar with the list of foods you should ate or avoid to help control your condition.

What is paricalcitol?

• Paricalcitol is a man-made form of vitamin D. Vitamin D is significant for the absorption of calcium from the stomach and for the functioning of calcium in the body.

• Paricalcitol is used to treat or prevent hyperparathyroidism (overactive parathyroid gland) in people with chronic kidney failure.

• Paricalcitol may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking paricalcitol?

• Do not use this medicine if you have ever had an allergic reaction to vitamin D, or if you have:

· tall levels of calcium in your blood (hypercalcemia); or

· tall levels of vitamin D in your body (vitamin D toxicity).

• If you have any of these another conditions, you may need a paricalcitol doze adjustment or particular tests:

· tall blood pressure;

· liver malady; or

· an electrolyte imbalance.

• FDA pregnancy category C. It is not known whether paricalcitol will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication..

• Your paricalcitol doze needs may change if you are breast-feeding a child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take paricalcitol?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Paricalcitol is sometimes taken daily, and sometimes taken each another day. Follow your doctor's instructions carefully.

• Your doctor may occasionally change your doze to create certain you get the excellent results.

• You may take this medicine with or without food.

• While using paricalcitol, you may need blood trials at your doctor's office. Visit your doctor regularly.

• Store at room temperature away from moisture, easy, and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of vitamin D can reason serious or life-threatening side effects.

What must I avoid while taking paricalcitol?

• Do not take another vitamin or mineral supplements unless your doctor has told you to.

• Avoid using calcium supplements or antacids without your doctor's advice. Use only the specific type of supplement or antacid your doctor recommends.

What are the possible side effects of paricalcitol?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop taking paricalcitol and call your doctor at once if you have a serious side effect such as:

· fever, chills, body aches, flu symptoms;

· chest pain, feeling short of breath;

· feeling like you might pass out;

· swelling, rapid weight gain;

· pain or burning when you urinate;

· dry mouth, drowsiness, heighten urination, quick heart course, feeling light-headed, fainting, or seizure (convulsions);

· nausea, loss of appetite, heighten thirst, muscle weakness, confusion, and feeling weary or restless;

· early signs of vitamin D overdose (weakness, metallic taste in your mouth, weight loss, muscle or bone pain, constipation, nausea, and vomiting).

• Smaller serious side effects may include:

· dizziness, spinning sensation;

· back pain, mild muscle or joint pain;

· stomach pain, indigestion;

· diarrhea;

· sore throat, cough, runny or stuffy nose; or

· mild itching or skin rash.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect paricalcitol?

• Speak your doctor about all another medicines you use, especially:

· cholestyramine (Prevalite, Questran);

· conivaptan (Vaprisol);

· digoxin (Lanoxin);

· imatinib (Gleevec);

· isoniazid (for treating tuberculosis);

· an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);

· antifungal medicine such as clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend);

· an antidepressant such as nefazodone;

· heart or blood pressure medicine such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others; or

· HIV/AIDS medication such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir).

• This list is not complete and another drugs may interact with paricalcitol. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about paricalcitol.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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