PAMIDRONATE

(PAM i DROE nate) Brand: Aredia

What is the most significant information I must know about pamidronate?

Do not use pamidronate if you are pregnant. It could harm the unborn baby.

• You must not use this medicine if you are allergic to pamidronate or to another bisphosphonates such as alendronate (Fosamax), etidronate (Didronel), ibandronate (Boniva), risedronate (Actonel), tiludronate (Skelid), or zoledronic acid (Reclast, Zometa).

• Till using pamidronate, speak your doctor if you have kidney malady, a history of thyroid surgery, or low levels of platelets or red blood cells.

• Some people using medicines similar to pamidronate have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery inclusion the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Another conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.

Pamidronate can harm your kidneys, and this effect is heighten when you also use determined another medicines deleterious to the kidneys. Till using pamidronate, speak your doctor about all another medications you use. Much another drugs (including some over-the-counter medicines) can be deleterious to the kidneys.

• Serious side effects of pamidronate include tall fever, severe bone pain, severe joint or muscle pain, urinating smaller than normal or not at all, swelling, rapid weight gain, eye pain, vision changes, confusion, uneven heart course, extreme thirst, muscle weakness or limp feeling, or seizure.

What is pamidronate?

Pamidronate is in a group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body.

Pamidronate is used to treat tall levels of calcium in the blood related to cancer (also called hypercalcemia of malignancy). Pamidronate is also used to treat Paget's malady of bone.

Pamidronate is used to treat bone hurt caused by determined types of cancer such as breast cancer or bone marrow cancer. Pamidronate does not treat cancer. Use all another medications your doctor has predesigned for those conditions.

Pamidronate may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till using pamidronate?

• You must not use this medicine if you are allergic to pamidronate or to another bisphosphonates such as alendronate (Fosamax), etidronate (Didronel), ibandronate (Boniva), risedronate (Actonel), tiludronate (Skelid), or zoledronic acid (Reclast, Zometa).

• To create certain you can safely use pamidronate, speak your doctor if you have any of these another conditions:

· kidney disease;

· a history of thyroid surgery; or

· low levels of platelets or red blood cells.

• Some people using medicines similar to pamidronate have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery inclusion the gums.

• You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Another conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and dental surgery or pre-existing dental problems.

• FDA pregnancy category D. Do not use pamidronate if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.

• It is not known whether pamidronate passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are using pamidronate.

How is pamidronate given?

Pamidronate is injected into a vein through an IV. This medicine should be given slowly, and the IV infusion can take 2 to 24 hours to complete. You may be shown how to use an IV at house. Do not self-inject this medication if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and another items used to inject the medicine.

Pamidronate is sometimes given as a single doze only one time. It may also be repeated over 3 days in a row, or given once each 3 to 4 weeks. How often you receive this medicine and the length of your infusion time will depend on the condition being treated. Follow your doctor's instructions.

• You may need to mix pamidronate with a liquid (diluent) in an IV bag till using it. If you are using the injections at house, be certain you understand how to properly mix and store the medicine. Never mix pamidronate with a solution that contains calcium (such as lactated Ringer's solution) or with another drugs in the same IV bag or line.

• Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Hold this container out of the reach of children and pets.

• If you do not have hypercalcemia, your doctor may want you to take calcium or vitamin D supplements by mouth while you are using pamidronate. Do not take any vitamin or mineral supplements that your doctor has not prescribed.

• To be certain this medication is helping your condition and is not causing deleterious effects, your blood will need to be tested often. Visit your doctor regularly.

• Store unmixed pamidronate at room temperature away from moisture and heat.

• After mixing pamidronate with a diluent, store in the refrigerator and use it within 24 hours. Do not freeze. Do not use the medicine if it has changed colors or has particles in it. Call your doctor for a new prescription.

What happens if I miss a dose?

• Call your doctor for instructions if you miss a doze of pamidronate.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while using pamidronate?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of pamidronate?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· tall fever;

· severe joint, bone, or muscle pain;

· new or unusual pain in your thigh or hip;

· urinating smaller than normal or not at all;

· swelling, rapid weight gain;

· pain or burning when you urinate;

· seizure (convulsions);

· eye pain, vision changes;

· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating; or

· confusion, uneven heart course, extreme thirst, heighten urination, leg discomfort, muscle weakness or limp feeling, or jerking muscle movements.

• Smaller serious side effects may include:

· low fever;

· stomach pain, loss of appetite, nausea, vomiting;

· constipation; or

· pain, redness, swelling or a heavy painful lump under your skin near the IV needle.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect pamidronate?

Pamidronate can harm your kidneys. This effect is heighten when you also use another medicines deleterious to the kidneys. You may need doze adjustments or particular trials if you have recently used:

· lithium (Lithobid);

· methotrexate (Rheumatrex, Trexall);

· pain or arthritis medicines such as aspirin (Anacin, Excedrin), acetaminophen (Tylenol), diclofenac (Cataflam, Voltaren), etodolac (Lodine), ibuprofen (Advil, Motrin), indomethacin (Indocin), naproxen (Aleve, Naprosyn), and others;

· medicines used to treat ulcerative colitis, such as mesalamine (Pentasa) or sulfasalazine (Azulfidine);

· medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune) or tacrolimus (Prograf);

· IV antibiotics such as amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet), amikacin (Amikin), bacitracin (Baci-IM), capreomycin (Capastat), gentamicin (Garamycin), kanamycin (Kantrex), streptomycin, or vancomycin (Vancocin, Vancoled);

· antiviral medicines such as adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); or

· cancer medication such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), streptozocin (Zanosar), or tretinoin (Vesanoid).

• This list is not complete and another drugs may interact with pamidronate. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about pamidronate.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

(9)
© 2006-2018 medpill.info Last Updated On: 11/12/2018 (0)
×
Wait 20 seconds...!!!