(AL des LOO kin) Brand: Proleukin
• Aldesleukin is a cancer medicine used to treat kidney or skin cancer that has spread to another parts of the body.
• You must not receive this medicine if you have recently had emergency lung or heart function tests.
• Aldesleukin can reason a serious blood vessel problem. Call your doctor at once if you have mood or behavior changes, confusion, chest pain, trouble breathing, bloody or tarry stools, or few or no urinating.
• Also speak your doctor if you feel very drowsy during treatment.
• Aldesleukin is a cancer medicine that interferes with tumor growth.
• Aldesleukin is used to treat kidney cancer or skin cancer than has spread to another parts of the body.
• Aldesleukin may also be used for purposes not listed in this medicine guide.
• You must not receive this medicine if you are allergic to aldesleukin or interleukin-2, or if you have:
· an infection caused by bacteria;
· if you have received an organ transplant;
· if you have recently had an emergency lung function test; or
· if you have recently had an emergency exercice test showing decreased blood flow to your heart.
• You may not be able to receive aldesleukin if you have had any of these side effects while receiving aldesleukin in the past:
· irregular heart rhythm;
· chest pain;
· a build-up of fluid near your heart;
· kidney failure;
· seizures;
· psychosis (thinking problems, hallucinations, or changes in personality);
· stomach or intestinal bleeding; or
· if you needed a breathing tube.
• To create certain you aldesleukin is safety for you, speak your doctor if you have:
· heart malady, angina (chest pain), a heart rhythm mess, or history of heart attack;
· lung or breathing problems;
· kidney disease;
· liver disease;
· gallbladder disease;
· tall levels of calcium in your blood (hypercalcemia);
· a thyroid disorder;
· diabetes;
· a seizure disorder;
· mental diseases or neurologic problems; or
· an autoimmune mess such as Crohn's malady, scleroderma, arthritis, myasthenia gravis, or a chronic skin disorder.
• FDA pregnancy category C. It is not known whether aldesleukin will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• It is not known whether aldesleukin passes into breast milk or if it could harm a nursing child. Speak your doctor if you are breast-feeding a baby.
• Aldesleukin is injected into a vein through an IV. A healthcare provider will give you this injection.
• Your breathing, blood pressure, oxygen levels, kidney function, and another vital signs will be watched closely while you are receiving aldesleukin. Your blood will also need to be tested daily during treatment, and you may also need chest x-rays.
• After 4 weeks off the medicine, your doctor will examine you to determine if you need to be treated again with aldesleukin.
• If you need to have any type of x-ray or CT scan using a paint that is injected into your veins, be certain the doctor knows onward of time if you have recently received aldesleukin. Some people treated with aldesleukin or similar medicine have had unusual allergic reactions to contrast agents used within weeks to different months later.
• Call your doctor for instructions if you miss an appointment for your aldesleukin injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have:
· severe drowsiness, feeling like you might pass out;
· chest pain, quick or pounding heartbeats;
· runny or stuffy nose, cough, rapid breathing and heart course, trouble breathing, swelling and pain in any part of your body;
· problems with vision, speech, balance, or coordination;
· mood or behavior changes, confusion, agitation, hallucinations;
· seizures (convulsions);
· swelling, rapid weight gain, few or no urinating;
· black, bloody, or tarry stools;
· a blistering skin rash;
· jaundice (yellowing of the skin or eyes); or
· signs of infection such as fever, chills, sore throat, flu symptoms, light bruising or bleeding (nosebleeds, bleeding gums), nausea and vomiting, mouth sores, unusual weakness.
• General side effects may include:
· mild stomach pain, diarrhea, loss of appetite.
· weary feeling; or
· drowsiness, dizziness, anxiety.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Taking aldesleukin with another drugs that create you sleepy or slow your breathing can magnify these effects. Ask your doctor till taking aldesleukin with a sleeping pill, narcotic pain medication, muscle relaxer, or medication for anxiety, depression, or seizures.
• Aldesleukin can harm your kidneys. This effect is heighten when you also use determined another medicines, including: antivirals, chemotherapy, injected antibiotics, medication for bowel disorders, medication to prevent organ transplant rejection, and some pain or arthritis medicines (including aspirin, Tylenol, Advil, and Aleve).
• Many another drugs may interact with aldesleukin, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual. Give a list of all your medicines to any healthcare provider who treats you.
• Your doctor or pharmacist can provide more information about aldesleukin.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.