MESALAMINE (ORAL)

(me SAL a meen) Brand: Apriso, Asacol, Asacol HD, Delzicol, Lialda, Pentasa

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What is the most significant information I must know about mesalamine oral?

Mesalamine is used to treat ulcerative colitis, proctitis, and proctosigmoiditis.

• Stop using mesalamine and call your doctor at once if you have severe stomach pain, cramping, fever, headache, and bloody diarrhea.

What is mesalamine oral?

Mesalamine affects a stuff in the body that causes inflammation, tissue hurt, and diarrhea.

Mesalamine is used to treat ulcerative colitis, proctitis, and proctosigmoiditis. Mesalamine is also used to prevent the symptoms of ulcerative colitis from recurring.

Mesalamine may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking mesalamine oral?

• You must not use this medicine if you are allergic to mesalamine or to aspirin or another salicylates (such as Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others).

• To create certain mesalamine is safety for you, speak your doctor if you have:

· a stomach condition called pyloric stenosis;

· a history of allergy to sulfasalazine (Azulfidine);

· heart disease;

· kidney malady; or

· liver disease.

• FDA pregnancy category C. It is not known whether mesalamine will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

Mesalamine can pass into breast milk and may harm a nursing child. Speak your doctor if you are breast-feeding a baby.

How must I take mesalamine oral?

• Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.

• Take mesalamine with a full glass of water.

Mesalamine can generally be taken with or without food. Follow your doctor's instructions.

Mesalamine extended-release capsules (Lialda) must be taken with a meal.

• Do not crush, interrupt, or chew a mesalamine tablet or capsule. Swallow the pill whole.

• The extended-release capsule is specially formulated to release the medication after it has passed through your stomach into your intestines. Breaking the pill may reason the drug to be released too early in the digestive tract.

• The enteric-coated tablet has a particular coating to protect your stomach. Breaking the pill could hurt this coating.

• Call your doctor if you find undissolved tablets in your stool.

• This medicine can reason unusual results with determined medical trials. Speak any doctor who treats you that you are taking mesalamine.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking mesalamine oral?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of mesalamine oral?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using mesalamine and call your doctor at once if you have:

· severe stomach pain, cramping, bloody diarrhea;

· fever, headache, skin rash;

· chest pain, shortness of breath;

· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· few or no urinating;

· swelling, rapid weight gain; or

· bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

• General side effects may include:

· mild stomach discomfort, gas;

· flu symptoms, runny nose;

· diarrhea, constipation;

· headache, dizziness;

· weakness; or

· joint pain.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect mesalamine oral?

• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with mesalamine, especially:

· amphotericin B;

· azathioprine or mercaptopurine;

· pentamidine;

· tacrolimus;

· an antibiotic--capreomycin, rifampin, vancomycin;

· antiviral medicines--acyclovir, adefovir, cidofovir, foscarnet;

· cancer medicine--aldesleukin, carmustine, cisplatin, ifosfamide, oxaliplatin, streptozocin, tretinoin; or

· NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

• This list is not complete and another drugs may interact with mesalamine. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about mesalamine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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