FOSCARNET

(fos KAR net) Brand: Foscavir

What is the most significant information I must know about foscarnet?

• Till using foscarnet, speak your doctor if you have kidney malady, a seizure mess, heart malady, a nerve mess, or an electrolyte imbalance such as low calcium, potassium, or magnesium.

• To be certain this medicine is not causing deleterious effects, your blood will need to be tested on a regular basis. Your kidney function may also need to be tested, and you may also need regular eye exams. Do not miss any scheduled visits to your doctor.

• Stop using foscarnet and call your doctor at once if you urinate smaller than normal or not at all, or if you have numbness or tingling near your mouth, uncontrolled muscle movements, or pain or burning when you urinate.

Foscarnet can be deleterious to the kidneys, and these effects are heighten when foscarnet is used together with another medicines that can harm the kidneys. Till using foscarnet, speak your doctor about all another medications you use. Much another drugs (including some over-the-counter medicines) can be deleterious to the kidneys.

Foscarnet is not a cure for CMV or HSV, and your virus may progress during or after treatment.

What is foscarnet?

Foscarnet is an antiviral medicine that prevents determined virus cells from multiplying in your body.

Foscarnet is used to treat cytomegalovirus (CMV) retinitis in people with AIDS.

Foscarnet is also used to treat herpes simplex virus (HSV) in people with a weak immune system. Foscarnet is generally given for HSV after another antiviral medications have been tried without successful treatment.

Foscarnet is not a cure for CMV or HSV, and your virus may progress during or after treatment.

Foscarnet may also be used for another purposes not listed in this medicine guide.

What must I discuss with my health care provider till using foscarnet?

• You must not use this medicine if you are allergic to foscarnet.

• If you have any of these another conditions, you may need a doze adjustment or particular trials to safely use this medication:

· kidney disease;

· epilepsy or another seizure disorder;

· a history of head injury or brain tumor;

· heart disease;

· a nerve disorder;

· low levels of calcium, magnesium, or potassium in your blood; or

· any another type of electrolyte imbalance.

• FDA pregnancy category C. It is not known whether foscarnet is deleterious to an unborn child. Till taking this medicine, speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether foscarnet passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How is foscarnet given?

Foscarnet is given as an injection through a needle placed into a vein. The medication should be given slowly through an IV infusion exhaust, and can take up to 2 hours to complete.

• You may be given instructions on how to inject your medication at house. Do not use this medication at house if you do not fully understand how to give the injection and properly dispose of needles and another items used in giving the medicine.

• With every foscarnet injection, you may be given IV fluids to hold you from getting dehydrated.

Foscarnet is generally given for 2 to 3 weeks. Your doctor may occasionally change your doze to create certain you get the excellent results from this medication.

• You may need to mix foscarnet with a liquid (diluent) till using it. If you are using the injections at house, be certain you understand how to properly mix and store the medicine. Do not give foscarnet with another medications in the same IV line.

Foscarnet must be clear and colorless. Do not use the medicine if it has changed colors or has any particles in it. Call your doctor for a new prescription.

• To be certain this medicine is not causing deleterious effects, your blood will need to be tested on a regular basis. Your kidney function may also need to be tested, and you may also need regular eye exams. Do not miss any scheduled visits to your doctor.

• Store foscarnet at room temperature away from very hot or very cool temperature.

What happens if I miss a dose?

• Use the medicine as soon as you remember the missed doze. If it is nearly time for your following doze, skip the missed doze and use the medication at your following regularly scheduled time. Do not use extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include numbness or tingling, thirst, drowsiness, confusion, urinating more or smaller than normal, muscle pain or weakness, quick heart course, feeling light-headed, fainting, or seizure (convulsions).

What must I avoid while using foscarnet?

• Avoid getting this medication in your eyes, as it may reason burning or irritation. If it does get into your eyes rinse with water and call your doctor.

What are the possible side effects of foscarnet?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using foscarnet and call your doctor at once if you have any of these serious side effects:

· urinating smaller than normal or not at all;

· drowsiness, confusion, mood changes, heighten thirst, loss of appetite, nausea and vomiting;

· swelling, weight gain, feeling short of breath;

· numbness or tingling near your mouth or in your hands or feet;

· dry mouth, heighten thirst, restless feeling, heighten urination, muscle pain or weakness, fainting, or seizure (convulsions);

· fever, chills, body aches, flu symptoms;

· pale skin, feeling light-headed, rapid heart course, trouble concentrating; or

· restless muscle movements in your eyes, tongue, jaw, or neck;

· trouble breathing; or

· pain or burning when you urinate.

• Smaller serious side effects may include:

· anxiety, depressed mood;

· stomach pain;

· headache, dizziness;

· cough;

· heighten sweating;

· skin rash;

· problems with vision;

· weary feeling;

· joint or muscle pain; or

· pain or swelling where the injection was given.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect foscarnet?

Foscarnet can harm your kidneys. This effect is heighten when you also use determined another medicines that can harm the kidneys. You may need doze adjustments or particular trials when using any of these medications together with foscarnet.

· amphotericin B (Abcelet, Ambisome);

· pentamidine (Nebupent, Pentam);

· antiviral medications;

· any injected antibiotics;

· medicines to treat a bowel disorder;

· medicine to prevent organ transplant rejection;

· pain or arthritis medicines; or

· HIV or AIDS medications such as ritonavir (Norvir) or saquinavir (Invirase).

• This list is not complete and there may be another drugs that can interact with foscarnet. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about foscarnet.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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