LORATADINE AND PSEUDOEPHEDRINE

(lor AT a deen and SOO doe ee FED rin) Brand: Alavert D-12, Claritin-D, Claritin-D 24 Hour, Leader Allergy Relief D-24, Loratadine-D 24 Hour

What is the most significant information I must know about loratadine and pseudoephedrine?

• Do not give this medicine to a baby younger than 4 years old. Always ask a doctor till giving a cough or cool medication to a child. Death can occur from the misuse of cough and cool medicines in very young children.

• Do not use loratadine and pseudoephedrine if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the recent 14 days. Serious, life threatening side effects can occur if you use loratadine and pseudoephedrine till the MAO inhibitor has cleared from your body.

• Ask a doctor or pharmacist till using any another cool, allergy, or sleep medication. Antihistamines and decongestants are contained in much combination medicines. Taking determined commodity together can reason you to get too many of a determined drug. Check the label to see if a medication contains an antihistamine or decongestant.

• This medicine may reason blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

• Drinking alcohol can magnify determined side effects of loratadine and pseudoephedrine.

What is loratadine and pseudoephedrine?

• Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can manufacture symptoms of sneezing, itching, watery eyes, and runny nose.

• Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can reason nasal congestion (stuffy nose).

• The combination of loratadine and pseudoephedrine is used to treat sneezing, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and another symptoms of allergies and the general cold.

• Loratadine and pseudoephedrine may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking loratadine and pseudoephedrine?

• Do not use this medicine if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the recent 14 days. Serious, life threatening side effects can occur if you use loratadine and pseudoephedrine till the MAO inhibitor has cleared from your body.

• Ask a doctor or pharmacist if it is safety for you to take this medicine if you have:

· kidney disease;

· glaucoma;

· heart malady or tall blood pressure;

· diabetes;

· thyroid disorder;

· an enlarged prostate; or

· problems with urination.

• FDA pregnancy category B. This medicine is not expected to harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether loratadine and pseudoephedrine passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take loratadine and pseudoephedrine?

• Use exactly as directed on the label, or as predesigned by your doctor. Do not use in larger or less amounts or for longer than recommended. Cool or allergy medication is generally taken only for a short time before your symptoms clear up.

• Do not crush, chew, or interrupt an extended-release tablet. Swallow it intact. Breaking the pill may reason too many of the drug to be released at one time.

• Conversation with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

• If you need to have surgery, speak the surgeon onward of time if you have taken a cool or allergy medication within the past little days.

• This medicine can reason unusual results with allergy skin trials. Speak any doctor who treats you that you are taking an antihistamine.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Since cool or allergy medication is taken as needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What must I avoid while taking loratadine and pseudoephedrine?

• This medicine may reason blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

• Drinking alcohol can magnify determined side effects of this medication.

• Avoid taking diet pills, caffeine pills, or another stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can magnify your risk of unpleasant side effects.

What are the possible side effects of loratadine and pseudoephedrine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using this medicine and call your doctor at once if you have a serious side effect such as:

· quick, pounding, or uneven heartbeat;

· confusion, hallucinations, unusual thoughts or behavior;

· severe dizziness, anxiety, restless feeling, or nervousness;

· dangerously tall blood pressure (severe headache, blurred vision, buzzing in your ears, chest pain, shortness of breath, uneven heartbeats, seizure);

· light bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

· urinating smaller than normal or not at all.

• Smaller serious side effects may include:

· blurred vision;

· dry mouth;

· nausea, stomach pain, constipation;

· mild loss of appetite, stomach upset;

· warmth, redness, or tingly feeling under your skin;

· sleep problems (insomnia);

· restless or excitability (especially in children);

· skin rash or itching;

· dizziness, drowsiness;

· problems with memory or concentration; or

· mild ringing in your ears.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect loratadine and pseudoephedrine?

• Cool or allergy medication, sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression or anxiety can add to sleepiness caused by loratadine. Speak your doctor if you regularly use any of these medicines, or any another cool or allergy medicine.

• Speak your doctor about all another medicines you use, especially:

· blood pressure medications;

· a diuretic (water pill);

· medicine to treat irritable bowel syndrome;

· bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);

· aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others);

· a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or

· an antidepressant such as amitriptyline (Elavil, Vanatrip), doxepin (Sinequan), desipramine (Norpramin), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others.

• This list is not complete and another drugs may interact with loratadine and pseudoephedrine. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about loratadine and pseudoephedrine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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