(FOS a PREP i tan t) Brand: Emend for Injection
• You must not use this medicine if you also take pimozide. Using these drugs together can reason unwanted or dangerous effects.
• Fosaprepitant blocks the actions of chemicals in the body that trigger nausea and vomiting.
• Fosaprepitant is used together with another medications to prevent nausea and vomiting that may be caused by chemotherapy.
• Fosaprepitant will only prevent nausea and vomiting. It will not treat nausea or vomiting that you already have.
• Fosaprepitant may also be used for purposes not listed in this medicine guide.
• You must not use this medicine if you are allergic to fosaprepitant, aprepitant (oral Emend), or polysorbate 80, or if you also take pimozide.
• Using fosaprepitant while you are also taking pimozide can reason unwanted or dangerous effects.
• To create certain you can fosaprepitant is safety for you, speak your doctor if you have liver disease.
• FDA pregnancy category B. Fosaprepitant is not expected to harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.
• Fosaprepitant can create birth control pills smaller effective. This effect can recent for up to 28 days after your recent doze of fosaprepitant. Ask your doctor about using non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while you are receiving fosaprepitant, and for at least 1 month after your treatment ends.
• It is not known whether fosaprepitant passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.
• Fosaprepitant is injected into a vein through an IV. A healthcare provider will give you this injection.
• The first doze of fosaprepitant is generally given 30 minutes till your chemotherapy treatment begins.
• You may also be given another medicines, including aprepitant capsules (Emend), to further help prevent nausea and vomiting.
• Fosaprepitant is not for long-term use.
• Since fosaprepitant injection is given only once on the first day of your chemotherapy treatment, you are not likely to be on a dosing schedule.
• Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
• Follow your doctor's instructions about any restrictions on food, beverages, or activity.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives, redness; difficulty breathing; flushing (warmth, redness, or tingly feeling); swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have pain, redness, swelling, or bruising where the medication was injected.
• General side effects may include:
· weakness, weary feeling;
· diarrhea, constipation;
· indigestion, belching, loss of appetite;
· headache;
· hiccups; or
· minor irritation or discomfort where the injection was given.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Much drugs can interact with fosaprepitant. Not all possible interactions are listed here. Speak your doctor about all your medications and any you start or stop using during treatment with fosaprepitant, especially:
· everolimus;
· tolbutamide;
· warfarin, Coumadin;
· an antibiotic--clarithromycin, telithromycin;
· an antidepressant--nefazodone, paroxetine;
· antifungal medication--itraconazole, ketoconazole;
· HIV/AIDS medication--atazanavir, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir;
· seizure medication--carbamazepine, phenytoin; or
· tuberculosis medication--rifabutin, rifampin, rifapentine.
• This list is not complete and much another drugs can interact with fosaprepitant. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity. Give a list of all your medicines to any healthcare provider who treats you.
• Your doctor or pharmacist can provide more information about fosaprepitant.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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