DESLORATADINE AND PSEUDOEPHEDRINE

(DES loe RAT a deen and SOO doe ee FED rin) Brand: Clarinex-D 12 Hour, Clarinex-D 24 Hour

What is the most significant information I must know about desloratadine and pseudoephedrine?

• Do not give this medicine to a baby younger than 2 years old. Always ask a doctor till giving a cough or cool medication to a child. Death can occur from the misuse of cough and cool medicines in very young children.

• Do not use any another over-the-counter cool, allergy, or sleep medicine without first asking your doctor or pharmacist. If you take determined commodity together you may accidentally take too many of a determined drug. Read the label of any another medication you are using to see if it contains an antihistamine or decongestant.

• Do not use a cough or cool medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cool medication till the MAO inhibitor has cleared from your body.

• Desloratadine and pseudoephedrine can reason side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

• Avoid drinking alcohol. It can magnify some of the side effects of this medication.

What is desloratadine and pseudoephedrine?

• Desloratadine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can manufacture symptoms of sneezing, itching, watery eyes, and runny nose.

• Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can reason nasal congestion (stuffy nose).

• The combination of desloratadine and pseudoephedrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and another symptoms of allergies and the general cold.

• Desloratadine and pseudoephedrine is for use in adults and children who are at least 12 years old.

• Desloratadine and pseudoephedrine may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking desloratadine and pseudoephedrine?

• Till taking this medicine, speak your doctor if you are allergic to desloratadine or pseudoephedrine, or if you have:

· kidney disease;

· diabetes;

· glaucoma;

· heart malady or tall blood pressure;

· a thyroid disorder;

· an enlarged prostate; or

· problems with urination.

• FDA pregnancy category C. It is not known whether desloratadine and pseudoephedrine is deleterious to an unborn child. Till using this medicine, speak your doctor if you are pregnant or plan to become pregnant during treatment.

• Desloratadine and pseudoephedrine can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take desloratadine and pseudoephedrine?

• Take this medicine exactly as it has been predesigned by your doctor. Do not use the medicine in larger amounts, or use it for longer than recommended. Follow the directions on your prescription label. Cool medication is generally taken only for a short time before your symptoms clear up.

• Take this medication with a full glass of water.

• Do not crush, chew, or interrupt an extended-release tablet. Swallow the pill intact. Breaking the pill may reason too many of the drug to be released at one time.

• Conversation with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

• If you need to have any type of surgery, speak the surgeon onward of time if you have taken a cool medication within the past little days.

• This medicine can reason you to have unusual results with allergy skin trials. Speak any doctor who treats you that you are taking an antihistamine.

• Store the medicine at room temperature away from moisture and heat.

What happens if I miss a dose?

• Since cool or allergy medication is generally taken only as needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. If it is nearly time for your following doze, skip the missed doze and take the medication at your following regularly scheduled time. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What must I avoid while taking desloratadine and pseudoephedrine?

• This medicine can reason side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

• Avoid drinking alcohol. It can magnify some of the side effects of this medication.

• Avoid taking diet pills, caffeine pills, or another stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can magnify your risk of unpleasant side effects.

What are the possible side effects of desloratadine and pseudoephedrine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using this medicine and call your doctor at once if you have a serious side effect such as:

· quick, pounding, or uneven heartbeat;

· confusion, hallucinations, unusual thoughts or behavior;

· severe dizziness, anxiety, restless feeling, or nervousness;

· dangerously tall blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure);

· light bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

· urinating smaller than normal or not at all.

• Smaller serious side effects may include:

· dry mouth;

· nausea, stomach pain, constipation;

· mild loss of appetite, stomach upset;

· warmth, redness, or tingly feeling under your skin;

· sleep problems (insomnia);

· feeling restless or excited (especially in children);

· skin rash or itching;

· dizziness, drowsiness; or

· problems with memory or concentration.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect desloratadine and pseudoephedrine?

• Till using this medicine, speak your doctor if you regularly use another medicines that create you sleepy (such as another cool or allergy medication, sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression, or anxiety). They can add to sleepiness caused by desloratadine and pseudoephedrine.

• Speak your doctor about all another medications you use, especially:

· medicines to treat tall blood pressure;

· a diuretic (water pill);

· medicine to treat irritable bowel syndrome;

· bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);

· salicylates such as aspirin, Backache Relief Extra Power, Novasal, Nuprin Backache Caplet, Doan's Pills Extra Power, Pepto-Bismol, Tricosal, and others;

· a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;

· an antidepressant such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.

• This list is not complete and there may be another drugs that can interact with desloratadine and pseudoephedrine. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about desloratadine and pseudoephedrine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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