ALISKIREN

(a LIS ke rin) Brand: Tekturna

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What is the most significant information I must know about aliskiren?

Do not use this medicine if you are pregnant. Aliskiren can reason injury or death to the unborn child if you take the medication during your second or third trimester. Stop using this medicine and speak your doctor right away if you become pregnant.

• Till you take aliskiren, speak your doctor if you have kidney malady, heart malady, if you are on a low-salt diet, or if you have ever had an allergic reaction to a heart or blood pressure medication.

• If you take aliskiren with meals, avoid high-fat foods. They can create it harder for your body to absorb aliskiren.

• Conditions that may reason very low blood pressure include: vomiting, diarrhea, hard sweating, heart malady, dialysis, a low-salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you must drink while taking aliskiren. Speak your doctor if you have a prolonged diseases that causes diarrhea or vomiting.

What is aliskiren?

Aliskiren is an anti-hypertensive (blood pressure lowering) medicine. It works by decreasing substances in the body that narrow blood vessels and raise blood pressure.

Aliskiren is used to treat tall blood pressure (hypertension).

Aliskiren may also be used for purposes not listed in this medicine guide.

What must I discuss with my health care provider till taking aliskiren?

• You must not take aliskiren if you are allergic to it.

If you have diabetes or kidney disease, you may not be able to take aliskiren if you are also taking any of the next heart or blood pressure medications:

· azilsartan (Edarbi, Edarbyclor), candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, Avalide), losartan (Cozaar, Hyzaar), olmesartan (Benicar), valsartan (Diovan), telmisartan (Micardis); or

· benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik, Tarka).

• To create certain you can safely take aliskiren, speak your doctor if you have any of these another conditions:

· kidney malady (or if you are on dialysis);

· heart disease;

· if you are on a low-salt diet; or

· if you have ever had an allergic reaction to an ACE (angiotensin converting enzyme) inhibitor medicine such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others.

• FDA pregnancy category D. Do not use this medicine if you are pregnant. Aliskiren can reason injury or death to the unborn child if you take the medication during your second or third trimester. Stop using this medicine and speak your doctor right away if you become pregnant.

• It is not known whether aliskiren passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take aliskiren?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Your doctor may occasionally change your doze to create certain you get the excellent results.

• Take aliskiren with a full glass of water.

• You may take aliskiren with or without food, but take it the same way each time.

• If you take aliskiren with meals, avoid high-fat foods. They can create it harder for your body to absorb aliskiren.

• Conditions that may reason very low blood pressure include: vomiting, diarrhea, hard sweating, heart malady, dialysis, a low-salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you must drink while taking aliskiren. Speak your doctor if you have a prolonged diseases that causes diarrhea or vomiting.

• If you are being treated for tall blood pressure, hold using this medicine even if you feel beautiful. Tall blood pressure often has no symptoms.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include feeling light-headed or fainting.

What must I avoid while taking aliskiren?

• Avoid drinking alcohol. It can further lower your blood pressure and may magnify some of the side effects of aliskiren.

• Do not use salt substitutes or potassium supplements while taking aliskiren, unless your doctor has told you to.

What are the possible side effects of aliskiren?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficult breathing; swelling of your person, lips, tongue, or throat.

If you have an allergic reaction to aliskiren you must not take it again.

• Call your doctor at once if you have a serious side effect such as:

· feeling light-headed, fainting;

· nausea with slow uneven heart course and a weak pulse;

· swelling near your eyes; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· stomach pain or upset, diarrhea, heartburn;

· itching or skin rash;

· headache, dizziness, weary feeling;

· back pain, joint pain or swelling; or

· stuffy nose, sore throat, cough.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect aliskiren?

• Speak your doctor about all another medicines you use, especially:

· atorvastatin (Lipitor);

· cyclosporine (Gengraf, Neoral, Sandimmune);

· furosemide (Lasix);

· antifungal medicine such as fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);

· non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;

· a potassium supplement such as K-Dur, Klor-Con;

· salt substitutes that contain potassium; or

· a diuretic (water pill).

• This list is not complete and another drugs may interact with aliskiren. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about aliskiren.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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