(e RIB ue lin) Brand: Halaven
• Do not use eribulin if you are pregnant. It could harm the unborn child.
• Till you receive eribulin, speak your doctor if you have liver or kidney malady, congestive heart failure, a heart rhythm mess, a private or family history of Long QT syndrome, or an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).
• Eribulin can lower blood cells that help your body fight infections. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these trials. Visit your doctor regularly.
• Avoid being around people who are sick or have infections. Speak your doctor at once if you develop signs of infection.
• Call your doctor at once if you have a serious side effect such as fever, chills, body aches, flu symptoms, mouth sores, pain or burning when you urinate, pale skin, feeling light-headed or short of breath, quick or uneven heart course, severe numbness or tingling in your hands and foots, extreme thirst, heighten urination, leg discomfort, muscle weakness or limp feeling.
• Tell your doctor about all another medicines you use.
• Eribulin is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
• Eribulin is used to treat breast cancer that has spread to another parts of the body.
• Eribulin is generally given after at least 2 another combinations of chemotherapy medications have been tried without successful treatment of symptoms.
• Eribulin may also be used for purposes not listed in this medicine guide.
• You must not use eribulin if you are allergic to it.
• To create certain you can safely take eribulin, speak your doctor if you have any of these another conditions:
· liver disease;
· kidney disease;
· slow heartbeats, congestive heart failure;
· heart rhythm disorder;
· private or family history of Long QT syndrome; or
· an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).
• FDA pregnancy category D. Do not use eribulin if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.
• It is not known whether eribulin passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are using eribulin.
• Eribulin is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting.
• Eribulin is generally given once for week for 2 weeks in a row, on days 1 and 8 of a 21-day treatment cycle. This 21-day cycle is then repeated before your doctor decides that eribulin is no longer an appropriate treatment for your condition. Follow your doctor's instructions.
• Eribulin can lower blood cells that help your body fight infections. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these trials. Your heart function may also need to be checked using an electrocardiograph or ECG (sometimes called an EKG). Visit your doctor regularly.
• Call your doctor for instructions if you miss an appointment for your eribulin injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose symptoms may include some of the serious side effects listed in this medicine guide.
• Avoid being around people who are sick or have infections. Speak your doctor at once if you develop signs of infection.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have a serious side effect such as:
· fever, chills, body aches, flu symptoms, sores in your mouth and throat;
· pain or burning when you urinate;
· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;
· severe numbness or tingling in your hands and feet;
· low potassium (confusion, uneven heart course, extreme thirst, heighten urination, leg discomfort, muscle weakness or limp feeling);
• Smaller serious side effects may include:
· weakness, weary feeling;
· hair loss;
· nausea, constipation, loss of appetite;
· headache; or
· muscle or joint pain.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all another medicines you use, especially:
· arsenic trioxide (Trisenox);
· tacrolimus (Prograf);
· an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam);
· an antidepressant such as amitriptylline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), or desipramine (Norpramin);
· anti-malaria medications such as chloroquine (Aralen), or mefloquine (Lariam);
· heart rhythm medication such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), or sotalol (Betapace);
· medication to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran);
· medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);
· migraine headache medication such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig);
· narcotic medicine such as methadone (Methadose, Diskets, Dolophine).
• There may be another drugs that can interact with eribulin. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.
• Your pharmacist can provide more information about eribulin.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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