DEXBROMPHENIRAMINE, HYDROCODONE, AND PHENYLEPHRINE

(DEX brom fen IR a meen, HYE dro KOE done, FEN il EFF rin) Brand: Cytuss-HC NR, H-C Tussive-NR, Histussin HC

What is the most significant information I must know about dexbrompheniramine, hydrocodone, and phenylephrine?

• Do not use this medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cough and cool medication till the MAO inhibitor has cleared from your body.

• You must not use dexbrompheniramine, hydrocodone, and phenylephrine if you are allergic to it, or if you have severe or uncontrolled tall blood pressure, coronary artery malady, ischemic heart malady (reduced circulation of blood to the heart), narrow-angle glaucoma, peptic ulcer, if you are unable to urinate, or if you are pregnant or breast-feeding.

• Hydrocodone may be habit-forming and should be used only by the face it was predesigned for. This medicine must never be shared with other face, especially somebody who has a history of drug abuse or addiction. Hold the medicine in a secure seat where others can't get to it.

• Always ask a doctor till giving cough or cool medication to a baby. Death can occur from the misuse of cough or cool medication in very young children. Dexbrompheniramine, hydrocodone, and phenylephrine must not be given to a baby younger than 6 years old.

What is dexbrompheniramine, hydrocodone, and phenylephrine?

• Brompheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can manufacture symptoms of sneezing, itching, watery eyes, and runny nose.

• Hydrocodone is a narcotic cough suppressant.

• Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can reason nasal congestion (stuffy nose).

• The combination of dexbrompheniramine, hydrocodone, and phenylephrine is used to treat nasal congestion, sneezing, runny nose, itchy or water eyes, and cough caused by allergies or the general cold.

• Dexbrompheniramine, hydrocodone, and phenylephrine may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking dexbrompheniramine, hydrocodone, and phenylephrine?

• You must not use dexbrompheniramine, hydrocodone, or phenylephrine, if you have ever had an allergic reaction to it, or if you have:

· severe or uncontrolled tall blood pressure;

· coronary artery disease;

· an enlarged prostate;

· narrow-angle glaucoma;

· peptic ulcer;

· asthma;

· pheochromocytoma;

· if you are breast-feeding a child; or

· if you are having an asthma attack.

• If you have determined conditions, you may need a doze adjustment or particular trials to safely take dexbrompheniramine, hydrocodone, and phenylephrine. Till taking this medicine, speak your doctor if you have:

· heart malady or tall blood pressure;

· asthma, COPD, or another breathing disorder;

· diabetes;

· glaucoma;

· thyroid disorder;

· a history of head injury or brain tumor;

· enlarged prostate, urination problems.

• FDA pregnancy category C. This medicine may be deleterious to an unborn child. Hydrocodone can reason breathing problems or addiction/withdrawal symptoms in a newborn. Do not take this medicine while you are pregnant.

• This medicine can pass into breast milk and may harm a nursing child. Do not take this medicine if you are breast-feeding a baby.

• Older adults may be more likely to have side effects from this medication.

How must I take dexbrompheniramine, hydrocodone, and phenylephrine?

• Take this medicine exactly as it was predesigned for you. Do not take the medicine in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Cool medication is generally taken for only a short time before your symptoms clear up.

• Take the medication with a full glass of water.

• Measure liquid medication with a particular dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

• Conversation with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache or skin rash.

• Store dexbrompheniramine, hydrocodone, and phenylephrine at room temperature away from moisture and heat.

• Hold track of how many of this medication has been used from the bottle. Hydrocodone is a drug of abuse and you must be aware if any face in the household is using this medication improperly or without a prescription.

What happens if I miss a dose?

• Since cough and cool medication is generally taken only as needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. If it is nearly time for your following doze, skip the missed doze and take the medication at your following regularly scheduled time. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medication. An overdose of hydrocodone can be fatal.

• Overdose symptoms may include feeling restless or hyperactive, agitation, dizziness, confusion, hallucinations, quick or uneven heart course, tremor, hallucinations, extreme drowsiness, loss of coordination, warmth or redness in your person, fever, cool or clammy skin, dilated pupils, pinpoint pupils, slow heart course, blue-colored lips or fingernails, seizure (convulsions), weak or shallow breathing, or breathing that stops.

What must I avoid while taking dexbrompheniramine, hydrocodone, and phenylephrine?

• This medicine can reason side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

• Avoid drinking alcohol while you are taking this medication.

• Speak your doctor if you regularly use another medicines that create you sleepy (such as pain medicine, sleeping pills, muscle relaxers, and medication for seizures, depression or anxiety). They can add to sleepiness caused by dexbrompheniramine, hydrocodone, and phenylephrine.

• Do not use any another over-the-counter cool, allergy, or pain medicine without first asking your doctor or pharmacist. Brompheniramine or phenylephrine are contained in much medicines accessible over the counter. If you take determined commodity together you may accidentally take too many of a determined drug. Read the label of any another medication you are using to see if it contains brompheniramine or phenylephrine.

What are the possible side effects of dexbrompheniramine, hydrocodone, and phenylephrine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using this medicine and call your doctor at once if you have any of these serious side effects:

· shallow breathing, slow heartbeat;

· quick or pounding heartbeat;

· slow heart course, weak pulse, fainting, slow breathing (breathing may stop);

· confusion, hallucinations, unusual thoughts or behavior;

· seizure (convulsions);

· painful or difficult urination;

· urinating smaller than normal or not at all; or

· severe dizziness, anxiety, fear, or tremors.

• Smaller serious side effects may include:

· dizziness, drowsiness, headache;

· feeling restless or nervous;

· sleep problems (insomnia);

· nausea, vomiting, heartburn, loss of appetite;

· dry mouth;

· heighten urination; or

· blurred vision.

• This is not a complete list of side effects and others may occur. Speak your doctor about any unusual or bothersome side effect. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect dexbrompheniramine, hydrocodone, and phenylephrine?

• Till taking this medicine, speak your doctor if you regularly use another medicines that create you sleepy (such as narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression, anxiety, or mental illness). They can add to sleepiness caused by dexbrompheniramine or hydrocodone.

• Also speak your doctor about all another medicines you use, especially:

· medicines to treat tall blood pressure;

· indomethacin (Indocin);

· mecamylamine (Inversine);

· methyldopa (Aldomet);

· reserpine;

· a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others; or

· an antidepressant such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.

• This list is not complete and there may be another drugs that can interact with dexbrompheniramine, hydrocodone, and phenylephrine. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about dexbrompheniramine, hydrocodone, and phenylephrine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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