AMPHOTERICIN B

(am foe TER i sin) Brand: Fungizone, Fungizone For Tissue Culture

What is the most significant information I must know about amphotericin B?

• Do not receive this medicine if you are allergic to any formulation of amphotericin B (Abelcet, AmBisome, Amphotec, or Fungizone).

• Till you receive amphotericin B, speak your doctor if you are allergic to any drugs, or if you have kidney malady or heart disease.

Amphotericin B is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting.

• The medication should be given slowly through an IV infusion, and can take up to 6 hours to complete.

Amphotericin B may need to be given for up to different weeks or months, depending on the infection being treated.

• Some people receiving an amphotericin B injection have had a reaction to the infusion (either when the medication is injected into the vein or within 1 to 3 hours afterward). Speak your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, feverish or cool, or if have a slow heartbeat, chest tightness, or trouble breathing.

What is amphotericin B?

Amphotericin B is an antibiotic that fights fungal infections in the body.

Amphotericin B is used to treat serious, life-threatening fungal infections. It is not for use in treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina.

• Amphotericin is generally given after another antifungal antibiotics have been tried without successful treatment of symptoms.

Amphotericin B may also be used for another purposes not listed in this medicine guide.

What must I discuss with my health care provider till I receive amphotericin B?

• You must not receive this medicine if you are allergic to any formulation of amphotericin B (Abelcet, AmBisome, Amphotec, or Fungizone).

• Till you receive amphotericin B, speak your doctor if you are allergic to any drugs, or if you have:

· kidney malady; or

· heart disease.

• If you have any of these conditions, you may need a doze adjustment or particular trials to safely receive amphotericin B.

• FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether amphotericin B passes into breast milk or if it could harm a nursing child. Do not receive this medicine without telling your doctor if you are breast-feeding a baby.

How is amphotericin B given?

Amphotericin B is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting.

• The medication should be given slowly through an IV infusion, and can take up to 6 hours to complete.

• While you are receiving your amphotericin B infusion, your caregivers will check your blood pressure, pulse, temperature, and lung function about each 30 minutes.

• To be certain this medicine is not causing deleterious effects, your blood cells, kidney function, and liver function may need to be tested on a regular basis. Amphotericin B can have long-lasting effects on your body. Do not miss any follow-up visits to your doctor for blood or urine tests.

Amphotericin B may need to be given for up to different weeks or months, depending on the infection being treated.

What happens if I miss a dose?

• Since amphotericin B is generally given while you are in the hospital, it is not likely you will miss a doze of this medication.

• If you are receiving amphotericin B in an outpatient clinic, call your doctor if you will miss an appointment for your amphotericin B injection.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include slow heart course, and shallow breathing that slows or stops.

What must I avoid while receiving amphotericin B?

Amphotericin B may lower the blood cells that help your body fight another infections. This can create it easier for you to bleed from an injury or get sick from being near others who are ill. Avoid being around people who have colds, the flu, or another contagious illnesses. Contact your doctor at once if you develop signs of infection.

What are the possible side effects of amphotericin B?

• Some people receiving an amphotericin B injection have had a reaction to the infusion (either when the medication is injected into the vein or within 1 to 3 hours afterward). Speak your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, feverish or cool, or if you have a slow heartbeat, chest tightness, or trouble breathing.

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Speak your doctor at once if you have any of these serious side effects:

· dry mouth, heighten thirst, nausea, vomiting;

· extreme drowsiness, restless feeling, confusion;

· urinating more or smaller than normal, or not at all;

· muscle pain or weakness, quick or uneven heart course, feeling light-headed, fainting;

· seizure (convulsions);

· fever, chills, body aches, flu symptoms;

· pale skin, light bruising or bleeding, unusual weakness; or

· nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

• Smaller serious side effects may include:

· pain, swelling, or another irritation where the needle is placed;

· mild nausea, vomiting, diarrhea, upset stomach, loss of appetite;

· weight loss;

· muscle or joint aches;

· headache;

· warmth, redness, or tingly feeling under your skin; or

· skin itching or mild rash.

• This is not a complete list of side effects and others may occur. Speak your doctor about any unusual or bothersome side effect. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect amphotericin B?

• Till receiving amphotericin B, speak your doctor if you are using any of the next drugs:

· flucytosine (Ancobon);

· digoxin (digitalis, Lanoxin, Lanoxicaps);

· pentamidine (Nebupent, Pentam);

· tacrolimus (Prograf);

· muscle relaxers;

· steroids (prednisone and others);

· antifungal antibiotics such as clotrimazole (Mycelex Troche), fluconazole (Diflucan), ketoconazole (Nizoral), or itraconazole (Sporanox);

· antibiotics such as capreomycin (Capastat), rifampin (Rifadin, Rimactane, Rifater), vancomycin (Vancocin, Vancoled);

· antiviral medicines such as acyclovir (Zovirax), adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); or

· cancer medication such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), plicamycin (Mithracin), streptozocin (Zanosar), or tretinoin (Vesanoid).

• This list is not complete and there may be another drugs that can interact with amphotericin B. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about amphotericin B.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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© 2006-2024 medpill.info Last Updated On: 03/11/2024 (0.03)
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