TOLMETIN

(TOLE met in) Brand: Tolectin

What is the most significant information I must know about tolmetin?

• This medication can magnify your risk of life-threatening heart or circulation problems, including heart onslaught or stroke. This risk will magnify the longer you use tolmetin. Do not use this medication just till or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

• Search abnormal medical help if you have symptoms of heart or circulation problems, such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

• This medication can also magnify your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal. These gastrointestinal effects can occur without warning at any time while you are taking tolmetin. Older adults may have an even greater risk of these serious gastrointestinal side effects.

• Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

• Do not use any another over-the-counter cool, allergy, or pain medicine without first asking your doctor or pharmacist. Much medicines accessible over the counter contain aspirin or another medicines similar to tolmetin (such as ibuprofen, ketoprofen, or naproxen). If you take determined commodity together you may accidentally take too many of this type of medicine. Read the label of any another medication you are using to see if it contains aspirin, ibuprofen, ketoprofen, or naproxen.

• Do not drink alcohol while taking tolmetin. Alcohol can magnify the risk of stomach bleeding caused by tolmetin.

What is tolmetin?

• Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that reason inflammation and pain in the body.

• Tolmetin is used to treat pain, inflammation, and stiffness caused by arthritis.

• Tolmetin may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking tolmetin?

• Taking an NSAID can magnify your risk of life-threatening heart or circulation problems, including heart onslaught or stroke. This risk will magnify the longer you use an NSAID. Do not use this medication just till or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

• NSAIDs can also magnify your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal. These gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.

• Do not use this medicine if you have ever had an allergic reaction to tolmetin, aspirin, or another NSAIDs.

• If you have any of these another conditions, you may need a doze adjustment or particular trials to safely take tolmetin:

· a history of heart onslaught, stroke, or blood clot;

· heart malady, congestive heart failure, tall blood pressure;

· a history of stomach ulcers or bleeding;

· liver or kidney disease;

· asthma;

· polyps in your nose;

· a bleeding or blood clotting mess; or

· if you smoke.

• FDA pregnancy category C. It is not known whether tolmetin is deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment. Taking tolmetin during the recent 3 months of pregnancy may result in birth defects. Do not take tolmetin during pregnancy unless your doctor has told you to.

• Tolmetin can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Do not give this medication to a baby younger than 2 years old without the advice of a doctor.

How must I take tolmetin?

• Take this medicine exactly as it was predesigned for you. Do not take the medicine in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

• Take this medication with a full glass of water.

• It is excellent to take tolmetin on an empty stomach. However, if tolmetin upsets your stomach you may take it with food, milk, or an antacid (but not sodium bicarbonate or baking soda).

• If you take tolmetin for a long period of time, your doctor may want to check you on a regular basis to create certain this medicine is not causing deleterious effects. Do not miss any scheduled visits to your doctor.

• You may need to take tolmetin for different days till you announcement improvement in your symptoms.

• Store tolmetin at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. If it is nearly time for your following doze, skip the missed doze and take the medication at the following regularly scheduled time. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medication. Overdose symptoms may include nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, shallow breathing, and fainting.

What must I avoid while taking tolmetin?

• Do not use any another over-the-counter cool, allergy, or pain medicine without first asking your doctor or pharmacist. Much medicines accessible over the counter contain aspirin or another medicines similar to tolmetin (such as ibuprofen, ketoprofen, or naproxen). If you take determined commodity together you may accidentally take too many of this type of medicine. Read the label of any another medication you are using to see if it contains aspirin, ibuprofen, ketoprofen, or naproxen.

• Do not drink alcohol while taking tolmetin. Alcohol can magnify the risk of stomach bleeding caused by tolmetin.

• Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Tolmetin can create your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you should be out in the sun.

What are the possible side effects of tolmetin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using tolmetin and call your doctor at once if you have any of these serious side effects:

· chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;

· black, bloody, or tarry stools;

· coughing up blood or vomit that looks like coffee grounds;

· swelling or rapid weight gain;

· urinating smaller than normal or not at all;

· nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

· bruising, severe tingling, numbness, pain, muscle weakness; or

· fever, headache, neck stiffness, chills, heighten sensitivity to easy, purple spots on the skin, and/or seizure (convulsions).

• Smaller serious side effects may include:

· upset stomach, mild heartburn, diarrhea, constipation;

· bloating, gas;

· dizziness, headache, nervousness;

· skin itching or rash;

· blurred vision; or

· ringing in your ears.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect tolmetin?

• Speak your doctor if you are taking an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). Taking any of these drugs with tolmetin may reason you to bruise or bleed easily.

• Till taking tolmetin, speak your doctor if you are using any of the next drugs:

· lithium (Eskalith, Lithobid);

· diuretics (water pills) such as furosemide (Lasix).

· methotrexate (Rheumatrex, Trexall);

· steroids (prednisone and others);

· a blood thinner such as warfarin (Coumadin);

· an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik); or.

· aspirin or another NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), and others;

• This list is not complete and there may be another drugs that can interact with tolmetin. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about tolmetin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.