SPIRONOLACTONE

(spir ON oh LAK tone) Brand: Aldactone

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What is the most significant information I must know about spironolactone?

• You must not use spironolactone if you are allergic to it, or if you have kidney malady, tall levels of potassium in your blood, or if you are unable to urinate. Do not use potassium supplements or another diuretics while you are taking spironolactone.

• Till using this medicine, speak your doctor if you have liver malady, or if you use a steroid or other diuretic.

• Drinking alcohol can magnify determined side effects of spironolactone.

• Avoid a diet tall in salt. Too many salt will reason your body to retain water and can create this medicine smaller effective.

• Do not use salt substitutes or low-sodium milk commodity that contain potassium. These commodity could reason your potassium levels to get too tall while you are taking spironolactone.

• Avoid becoming overheated or dehydrated during exercice and in hot weather. Follow your doctor's instructions about the type and amount of liquids you must drink. In some cases, drinking too many liquid can be as unsafe as not drinking enough.

• If you are being treated for tall blood pressure, hold using this medicine even if you feel well. Tall blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

What is spironolactone?

Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too many salt and keeps your potassium levels from getting too low.

Spironolactone is used to diagnose or treat a condition in which you have too many aldosterone in your body. Aldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your body.

Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney mess called nephrotic syndrome. This medicine is also used to treat or prevent hypokalemia (low potassium levels in the blood).

Spironolactone may also be used for purposes not listed in this medicine guide.

What must I discuss with my doctor till taking spironolactone?

• You must not use spironolactone if you are allergic to it, or if you have:

· kidney malady, or if you are unable to urinate;

· tall levels of potassium in your blood (hyperkalemia); or

· if you are taking potassium supplements or another potassium-sparing diuretics such as Aldactazide, amiloride (Midamor, Moduretic), or triamterene (Dyrenium, Dyazide, Maxzide).

• To create certain you can safely take spironolactone, speak your doctor if you have any of these another conditions:

· heart disease;

· liver malady; or

· if you are using a steroid, or other diuretic.

• FDA pregnancy category C. It is not known whether spironolactone will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

Spironolactone passes into breast milk and could reason harm to a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take spironolactone?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Take every doze with a full glass of water.

• To be certain this medication is not causing deleterious effects, your blood will need to be tested often. Visit your doctor regularly.

• This medicine can reason unusual results with determined medical trials. Speak any doctor who treats you that you are using spironolactone.

• If you need surgery, speak the surgeon onward of time that you are using spironolactone. You may need to stop using the medication for a short time.

• If you are being treated for tall blood pressure, hold using this medicine even if you feel well. Tall blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

• Store at room temperature away from heat, easy, and moisture.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include drowsiness, confusion, red skin rash, nausea, vomiting, or diarrhea.

What must I avoid while taking spironolactone?

• Drinking alcohol can magnify determined side effects of spironolactone.

• Do not use salt substitutes or low-sodium milk commodity that contain potassium. These commodity could reason your potassium levels to get too tall while you are taking spironolactone.

• Avoid a diet tall in salt. Too many salt will reason your body to retain water and can create this medicine smaller effective.

Spironolactone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Avoid becoming overheated or dehydrated during exercice and in hot weather. Follow your doctor's instructions about the type and amount of liquids you must drink. In some cases, drinking too many liquid can be as unsafe as not drinking enough.

What are the possible side effects of spironolactone?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using spironolactone and call your doctor at once if you have a serious side effect such as:

· numbness or tingly feeling;

· muscle pain or weakness;

· slow, quick, or uneven heart rate;

· feeling drowsy, restless, or light-headed;

· urinating smaller than normal or not at all;

· shallow breathing;

· tremors, confusion;

· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· mild nausea or vomiting;

· dizziness, headache;

· gas, stomach pain; or

· skin rash.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect spironolactone?

• Till using spironolactone, speak your doctor if you regularly use another medicines that create you sleepy (such as cool or allergy medication, sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression, or anxiety). They can add to sleepiness caused by spironolactone.

• Speak your doctor about all another medicines you use, especially:

· lithium (Eskalith, Lithobid);

· digoxin (digitalis, Lanoxin);

· steroids such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others;

· an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik); or

· an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others.

• This list is not complete and another drugs may interact with spironolactone. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about spironolactone.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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