SALSALATE

(SAL sa late) Brand: Disalcid, Salsitab

What is the most significant information I must know about salsalate?

• You must not use this medicine if you are allergic to aspirin or to an NSAID (non-steroidal anti-inflammatory drug).

• Till taking salsalate, speak your doctor if you have asthma, heart malady, tall blood pressure, stomach or intestinal bleeding, diabetes, anemia, a bleeding mess, liver or kidney malady, nasal polyps, a genetic enzyme deficiency, or if you are dehydrated.

• This medication may reason life-threatening heart or circulation problems such as heart onslaught or stroke, especially if you use it long term. Do not use salsalate just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• Get abnormal medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

• This medication may also reason serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking salsalate, especially in older adults.

• Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

• This medicine must not be given to a baby or teenager who has a fever, especially if the baby also has flu symptoms or chicken pox. Salicylates can reason a serious and sometimes fatal condition called Reye's syndrome in children.

What is salsalate?

• Salsalate is a non-steroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates). This medication works by reducing substances in the body that reason pain, fever, and inflammation.

• Salsalate is used to reduce pain, swelling, and joint stiffness caused by arthritis.

• Salsalate may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking salsalate?

• Salicylates may reason life-threatening heart or circulation problems such as heart onslaught or stroke, especially if you use it long term. Do not use salsalate just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• Salicylates may also reason serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking salsalate, especially in older adults.

• You must not use this medicine if you are allergic to aspirin or to an NSAID (non-steroidal anti-inflammatory drug).

• To create certain you can safely take salsalate, speak your doctor if you have any of these another conditions:

· asthma;

· heart malady, tall blood pressure, congestive heart failure;

· a history of stroke or heart attack;

· a stomach ulcer or intestinal bleeding;

· a bleeding or blood clotting disorder;

· diabetes;

· swelling or fluid retention;

· anemia (a lack of red blood cells);

· liver disease;

· kidney disease;

· an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

· nasal polyps; or

· if you are dehydrated.

• FDA pregnancy category C. Salsalate may be deleterious to an unborn child if the mother takes the medicine during the recent 3 months of pregnancy. Do not take this medicine without telling your doctor if you are pregnant or plan to become pregnant during treatment.

• Salsalate can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Older adults may be more likely to have side effects from salsalate.

How must I take salsalate?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Salsalate may be taken up to 3 times for day. Follow your doctor's instructions.

• Take the medication with a full glass of water.

• Take salsalate with food, milk, or an antacid if it upsets your stomach. To prevent stomach upset, do not lie down for at least 30 minutes after taking salsalate.

• It may take up to 2 weeks till your symptoms improve. Hold using the medicine as directed and speak your doctor if your symptoms do not improve after 2 weeks of treatment.

• This medicine can reason unusual results with determined medical trials. Speak any doctor who treats you that you are using salsalate.

• If you need surgery, speak the surgeon onward of time that you are using salsalate. You may need to stop using the medication for a short time.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Since salsalate is taken as needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include ringing in your ears, severe dizziness or drowsiness, sweating, quick breathing, severe vomiting or diarrhea, confusion, or seizure (convulsions).

What must I avoid while taking salsalate?

• Salsalate may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Ask a doctor or pharmacist till using any another over-the-counter medication. Salicylates and NSAIDs are contained in much combination medicines. Taking determined commodity together can reason you to get too many of a determined drug. Check the label to see if a medication contains aspirin, ibuprofen, naproxen, ketoprofen, magnesium salicylate, or similar medicines.

• If you are also taking low-dose aspirin because your doctor has predesigned it to prevent heart onslaught or stroke, do not stop taking it or change your doze without your doctor's advice. Aspirin must be used for cardiovascular conditions only under the supervision of a doctor.

• Avoid drinking alcohol. It may magnify your risk of stomach bleeding.

• Avoid smoking, since it can also magnify your risk of stomach bleeding.

What are the possible side effects of salsalate?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Stop using this medicine and call your doctor at once if you have a serious side effect such as:

· chest pain, severe dizziness, shortness of breath, slurred speech, problems with vision or balance;

· sudden numbness or weakness, especially on one side of the body;

· feeling like you might pass out;

· black, bloody, or tarry stools;

· coughing up blood or vomit that looks like coffee grounds;

· hearing problems, ringing in your ears;

· swelling in your hands or foots, rapid weight gain;

· quick or pounding heartbeats;

· light bruising or bleeding, fever, chills, sore throat, flu symptoms;

· urinating more or smaller than usual;

· severe stomach pain, ongoing nausea or vomiting; or

· dark urine, jaundice (yellowing of the skin or eyes).

• Smaller serious side effects may include:

· upset stomach, heartburn; or

· mild dizziness.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect salsalate?

• Much drugs can interact with salsalate. Adown is just a partial list. Speak your doctor if you are using:

· acetazolamide (Diamox);

· cyclosporine (Gengraf, Neoral, Sandimmune);

· lithium (Eskalith, LithoBid);

· methotrexate (Rheumatrex, Trexall);

· pemetrexed (Alimta);

· tenofovir (Viread);

· an antidepressant such as fluoxetine (Prozac) or sertraline (Zoloft);

· a blood thinner such as warfarin (Coumadin);

· oral diabetes medication;

· a diuretic (water pill);

· gout medicine such as probenecid (Benemid);

· heart or blood pressure medicine such as atenolol (Tenormin), captopril (Capoten), lisinopril (Prinivil, Zestril), losartan (Cozaar, Hyzaar), metoprolol (Lopressor, Toprol), and others;

· medicine used to prevent blood clots, such as cilostazol (Pletal) or clopidogrel (Plavix);

· osteoporosis medicine such as alendronate (Fosamax), ibandronate (Boniva), risedronate (Actonel), and others;

· sodium bicarbonate, potassium citrate (K-Lyte, Urocit-K), sodium citrate and citric acid (Bicitra, Oracit), or sodium citrate and potassium (Citrolith, Polycitra);

· seizure medicine such as phenytoin (Dilantin), phenobarbital (Solfoton), valproic acid (Depakene); or

· steroid medication (prednisone and others).

• This list is not complete and there are much another drugs that can interact with salsalate. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor. Hold a list of all your medicines and show it to any healthcare provider who treats you.

Where can I get more information?

• Your pharmacist can provide more information about salsalate.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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