NOREPINEPHRINE

(nor ep i NEF rin) Brand: Levophed Bitartrate

What is the most significant information I must know about norepinephrine?

• If possible till receiving norepinephrine, speak your doctor if you have tall blood pressure, diabetes, coronary artery malady, circulation problems, varicose veins, overactive thyroid, asthma, or a sulfite allergy.

• Also speak your doctor about all another medicines you use, especially blood pressure medicine or an antidepressant.

• In an abnormal situation it may not be possible till you are treated to speak your caregivers about your health conditions or if you are pregnant or breast feeding. Create certain any doctor caring for you afterward knows that you have received this medication.

• Speak your caregivers at once if you have a serious side effect such as cool feeling anywhere in your body, blue lips or fingernails, trouble breathing, urinating smaller than normal, irritation or skin changes where the medication is injected, slow heart course, sudden numbness or weakness, confusion, severe headache, or problems with vision, speech, or balance.

What is norepinephrine?

Norepinephrine is similar to adrenaline. It works by constricting (narrowing) the blood vessels and increasing blood pressure and blood glucose (sugar) levels.

Norepinephrine is used to treat life-threatening low blood pressure (hypotension) that can occur with determined medical conditions or surgical procedures. This medicine is often used during CPR (cardio-pulmonary resuscitation).

Norepinephrine may also be used for purposes not listed in this medicine guide.

What must I discuss with my health care provider till receiving norepinephrine?

• If possible till you receive norepinephrine, speak your doctor if you have:

· tall blood pressure (hypertension);

· diabetes;

· coronary artery disease;

· circulation problems;

· varicose veins;

· overactive thyroid; or

· asthma or a sulfite allergy.

• FDA pregnancy category C. It is not known whether norepinephrine will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• It is not known whether norepinephrine passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• In an abnormal situation it may not be possible till you are treated with norepinephrine to speak your caregivers if you are pregnant or breast feeding. Create certain any doctor caring for your pregnancy or your child knows you have received this medication.

How is norepinephrine given?

Norepinephrine is injected into a vein through an IV. You will receive this injection in a hospital or abnormal setting.

Norepinephrine is generally given for as long as needed before your body responds to the medicine. Some people should receive norepinephrine for different days.

• Your blood pressure, breathing, and another vital signs will be watched closely while you are receiving norepinephrine.

• Speak your caregivers if you feel any pain, irritation, cool feeling, or another discomfort of your skin or veins where the medication is injected. Norepinephrine can hurt the skin or tissues near the injection site if the medicine accidentally leaks out of the vein.

What happens if I miss a dose?

• Since norepinephrine is given by a healthcare professional in an abnormal setting, you are not likely to miss a dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include slow heart course or severe headache, sweating, vomiting, heighten sensitivity to easy, pale skin, and stabbing chest pain.

What must I avoid while receiving norepinephrine?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of norepinephrine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Speak your caregivers at once if you have a serious side effect such as:

· pain, burning, irritation, discoloration, or skin changes where the injection is given;

· sudden numbness, weakness, or cool feeling anywhere in your body;

· slow or uneven heart rate;

· blue lips or fingernails, mottled skin;

· urinating smaller than normal or not at all;

· trouble breathing;

· problems with vision, speech, or balance; or

· dangerously tall blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect norepinephrine?

• If possible till you receive norepinephrine, speak your doctor about all another medicines you use, especially:

· blood pressure medications;

· an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate); or

· an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan, Silenor), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).

• This list is not complete and another drugs may interact with norepinephrine. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about norepinephrine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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