HYDROCHLOROTHIAZIDE AND LISINOPRIL
(HYE droe KLOR oh THYE a zide and lye SIN oh pril) Brand: Prinzide, Zestoretic
What is the most significant information I must know about hydrochlorothiazide and lisinopril?
• Do not use if you are pregnant. Stop using this medicine and speak your doctor right away if you become pregnant.
• You must not use this medicine if you have hereditary angioedema, if you are unable to urinate, if you are allergic to sulfa drugs, or if you have ever had a severe allergic reaction to any ACE inhibitor.
• If you have diabetes, do not use hydrochlorothiazide and lisinopril together with any medicine that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).
What is hydrochlorothiazide and lisinopril?
• Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too many salt, which can reason fluid retention.
• Lisinopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Lisinopril lowers blood pressure and also relieves symptoms of fluid retention.
• Hydrochlorothiazide and lisinopril is a combination medication used to treat hypertension (high blood pressure).
• Hydrochlorothiazide and lisinopril may also be used for purposes not listed in this medicine guide.
What must I discuss with my healthcare provider till taking hydrochlorothiazide and lisinopril?
• You must not use this medicine if you are allergic to hydrochlorothiazide or lisinopril, or if you have:
· hereditary angioedema;
· if you are unable to urinate;
· an allergy to sulfa drugs; or
· if you have ever had a severe allergic reaction to any ACE inhibitor (benazepril, captopril, enalapril, fosinopril, moexipril, perindopril, quinapril, ramipril, trandolapril).
• If you have diabetes, do not use hydrochlorothiazide and lisinopril together with any medicine that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).
• You may also need to avoid taking hydrochlorothiazide and lisinopril with aliskiren if you have kidney disease.
• To create certain hydrochlorothiazide and lisinopril is safety for you, speak your doctor if you have:
· kidney malady (or if you are on dialysis);
· liver disease;
· glaucoma;
· heart malady or congestive heart failure;
· gout;
· lupus;
· diabetes; or
· an allergy to sulfa drugs or penicillin.
• FDA pregnancy category D. Do not use if you are pregnant. Stop using and speak your doctor right away if you become pregnant. Hydrochlorothiazide and lisinopril can reason injury or death to the unborn child if you take the medication during your second or third trimester. Use effective birth control.
• Hydrochlorothiazide and lisinopril can pass into breast milk and may harm a nursing child. Speak your doctor if you are breast-feeding a baby.
How must I take hydrochlorothiazide and lisinopril?
• Follow all directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results. Do not take this medication in larger or less amounts or for longer than recommended.
• Take every doze with a full glass of water.
• You may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than normal.
• While using hydrochlorothiazide and lisinopril, you may need frequent blood trials at your doctor's office. Your blood pressure will need to be checked often.
• If you need surgery or medical trials, speak the doctor onward of time that you are taking medicine that contains hydrochlorothiazide. You may need to stop using the medication for a short time.
• Keep using this medication as directed, even if you feel well. Tall blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.
• Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
What happens if I overdose?
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
What must I avoid while taking hydrochlorothiazide and lisinopril?
• Drinking alcohol can magnify determined side effects of hydrochlorothiazide and lisinopril.
• Avoid getting up too quick from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
• Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking hydrochlorothiazide and lisinopril, unless your doctor has told you to.
What are the possible side effects of hydrochlorothiazide and lisinopril?
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have:
· a light-headed feeling, like you might pass out;
· eye pain, vision problems;
· tall potassium (slow heart course, weak pulse, muscle weakness, tingly feeling);
· low potassium (confusion, uneven heart course, extreme thirst, heighten urination, leg discomfort, muscle weakness or limp feeling);
· dry mouth, nausea, vomiting;
· feeling weak, drowsy, or restless;
· a red, blistering, peeling skin rash;
· psoriasis (raised, silvery flaking of the skin);
· jaundice (yellowing of the skin or eyes);
· few or no urinating;
· swelling, weight gain, feeling short of breath; or
· fever, chills, body aches, flu symptoms.
• General side effects may include:
· cough;
· headache, weary feeling, depressed mood;
· diarrhea, constipation, upset stomach; or
· mild skin rash, heighten sweating.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
What another drugs will affect hydrochlorothiazide and lisinopril?
• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with hydrochlorothiazide and lisinopril, especially:
· barbiturates--phenobarbital and others;
· cholestyramine or colestipol;
· gold injections to treat arthritis;
· insulin or diabetes medication taken by mouth;
· lithium;
· narcotic pain medicine;
· NSAIDs (non-steroidal anti-inflammatory drugs)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;
· another diuretics (water pills) or blood pressure medications; or
· steroids (prednisone and others).
• This list is not complete. Another drugs may interact with hydrochlorothiazide and lisinopril, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.
Where can I get more information?
• Your pharmacist can provide more information about hydrochlorothiazide and lisinopril.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.