HYDROCHLOROTHIAZIDE AND CAPTOPRIL

(hye droe klor oh THY a zide and KAP toe pril) Brand: Capozide 25/15, Capozide 25/25, Capozide 50/15, Capozide 50/25

What is the most significant information I must know about hydrochlorothiazide and captopril?

• You must not use this medicine if you are allergic to hydrochlorothiazide or captopril, or if you have a history of asthma or allergies, or you are unable to urinate.

• You must not use this medicine if you are allergic to any another ACE inhibitor, such as benazepril (Lotensin), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

• Till taking hydrochlorothiazide and captopril, speak your doctor if you have kidney malady (or are on dialysis), liver malady, glaucoma, congestive heart failure, gout, lupus, diabetes, or an allergy to sulfa drugs or penicillin.

• Do not use hydrochlorothiazide and captopril if you are pregnant. It could harm the unborn baby.

• Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and captopril, unless your doctor has told you to.

• Conditions that may reason very low blood pressure include: vomiting, diarrhea, hard sweating, heart malady, dialysis, a low-salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you must drink while taking hydrochlorothiazide and captopril. Speak your doctor if you have a prolonged diseases that causes diarrhea or vomiting.

What is hydrochlorothiazide and captopril?

• Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too many salt, which can reason fluid retention.

• Captopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Captopril lowers blood pressure and also relieves symptoms of fluid retention.

• The combination of hydrochlorothiazide and captopril is used to treat hypertension (high blood pressure).

• Hydrochlorothiazide and captopril may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking hydrochlorothiazide and captopril?

• Do not use this medicine if you are allergic to hydrochlorothiazide or captopril, or if you have:

· a history of asthma or allergies; or

· if you are unable to urinate.

• To create certain you can safely take hydrochlorothiazide and captopril, speak your doctor if you have any of these another conditions:

· kidney malady (or if you are on dialysis);

· liver disease;

· glaucoma;

· congestive heart failure;

· gout;

· lupus;

· diabetes; or

· an allergy to sulfa drugs or penicillin

• FDA pregnancy category D. Do not use hydrochlorothiazide and captopril if you are pregnant. It could harm the unborn child. Stop using this medicine and speak your doctor right away if you become pregnant. Use effective birth control while taking hydrochlorothiazide and captopril.

• Hydrochlorothiazide can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take hydrochlorothiazide and captopril?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Your doctor may occasionally change your doze to create certain you get the excellent results.

• Take every doze with a full glass of water.

• Your blood pressure will need to be checked often. Your blood and urine may also be tested if you have been vomiting or are dehydrated. Visit your doctor regularly.

• If you need surgery or medical trials, speak the doctor onward of time that you are taking medicine that contains hydrochlorothiazide. You may need to stop using the medication for a short time.

• Hold using this medication as directed, even if you feel well. Tall blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

• Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include nausea, weakness, dizziness, dry mouth, thirst, muscle pain or weakness, or feeling like you might pass out.

What must I avoid while taking hydrochlorothiazide and captopril?

• Avoid becoming overheated or dehydrated during exercice and in hot weather. Follow your doctor's instructions about the type and amount of liquids you must drink. In some cases, drinking too many liquid can be as unsafe as not drinking enough.

• Avoid getting up too quick from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

• Drinking alcohol can further lower your blood pressure and may magnify determined side effects of hydrochlorothiazide and captopril.

• Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and captopril, unless your doctor has told you to.

What are the possible side effects of hydrochlorothiazide and captopril?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· eye pain, vision problems;

· tall potassium (slow heart course, weak pulse, muscle weakness, tingly feeling);

· low potassium (confusion, uneven heart course, extreme thirst, heighten urination, leg discomfort, muscle weakness or limp feeling);

· dry mouth, thirst, nausea, vomiting;

· feeling weak, drowsy, restless, or light-headed;

· a red, blistering, peeling skin rash;

· jaundice (yellowing of the skin or eyes);

· urinating smaller than normal or not at all;

· swelling, weight gain, feeling short of breath; or

· fever, chills, body aches, flu symptoms.

• Smaller serious side effects may include:

· cough;

· dizziness, headache, weary feeling;

· blurred vision;

· diarrhea, constipation, upset stomach; or

· mild skin rash, heighten sweating.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect hydrochlorothiazide and captopril?

• Cool or allergy medication, sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression or anxiety can add to the side effects of hydrochlorothiazide and captopril. Speak your doctor if you regularly use any of these medicines, or any another blood pressure medications.

• Speak your doctor about all another medicines you use, especially:

· gold injections to treat arthritis;

· another diuretics (water pills) or blood pressure medications;

· lithium (Lithobid, Eskalith);

· a blood thinner such as warfarin (Coumadin, Jantoven);

· digoxin (Lanoxin);

· nitroglycerin (Nitrolingual, Nitrostat, Nitro-Dur, and others);

· cholestyramine (Prevalite, Questran) or colestipol (Colestid);

· steroids (prednisone and others);

· NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others; or

· insulin or diabetes medication taken by mouth.

• This list is not complete and another drugs may interact with hydrochlorothiazide and captopril. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about hydrochlorothiazide and captopril.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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