OMEPRAZOLE AND SODIUM BICARBONATE

(oh ME pray zol and SO dee um by KAR bon ate) Brand: Zegerid, Zegerid OTC

What is the most significant information I must know about omeprazole and sodium bicarbonate?

• Omeprazole and sodium bicarbonate is a combination medication used to treat heartburn and another symptoms of gastroesophageal reflux malady (GERD). This medication is also used to treat ulcers and another conditions inclusion overweening stomach acid manufacture. Symptom relief does not mean that serious stomach problems (like cancer) do not exist. Conversation to your doctor if old stomach symptoms return or new symptoms appear.

• This medicine contains sodium bicarbonate, a form of salt. If you are on a low-salt or low-sodium diet, you may not be able to use omeprazole and sodium bicarbonate. Conversation with your doctor.

• This medicine can reason diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking omeprazole and sodium bicarbonate and call your doctor. Do not use anti-diarrhea medication unless your doctor tells you to.

What is omeprazole and sodium bicarbonate?

• Omeprazole is a proton exhaust inhibitor that decreases the amount of acid your stomach produces. Sodium bicarbonate is an antacid that raises the pH in your stomach to hold the omeprazole from breaking down in stomach acid.

• Omeprazole and sodium bicarbonate is not for immediate relief of heartburn symptoms.

• Omeprazole and sodium bicarbonate may also be used for purposes not listed in this medicine guide.

What must I discuss with my health care provider till taking omeprazole and sodium bicarbonate?

• Heartburn is often confused with the first symptoms of a heart onslaught. Search abnormal medical attention if you have chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, and a common ill feeling.

• You must not take this medicine if you are allergic to omeprazole or sodium bicarbonate.

• This medication contains sodium bicarbonate, a form of salt. Every capsule contains the equivalent of 300 mg of sodium. Every packet of powder contains the equivalent of 460 mg of sodium. If you are on a low-salt or low-sodium diet, you may not be able to use omeprazole and sodium bicarbonate. Conversation with your doctor.

• To create certain this medication is safety for you, speak your doctor if you have:

· kidney or liver disease;

· heart disease;

· metabolic or respiratory alkalosis (usually after prolonged illness); or

· low levels of calcium, magnesium, or potassium levels in your blood.

• Some people taking omeprazole may have an heighten risk of bone fracture in the hip, wrist, or spine. This effect has occurred mostly in people taking omeprazole long term or at tall doses, and in people who are age 50 and older. Omeprazole may not be the actual reason of heighten fracture risk. Till you take this medicine, speak your doctor if you have a bone disorder.

• Some conditions are treated with a combination of antibiotics with omeprazole and sodium bicarbonate. Use all medications as directed by your doctor. Read the medicine manual or patient instructions provided with every medicine. Do not change your doses or medicine schedule without your doctor's advice.

• FDA pregnancy category C. It is not known whether omeprazole and sodium bicarbonate will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• Omeprazole and sodium bicarbonate can pass into breast milk and may harm a nursing child. You must not breast-feed while using this medicine.

How must I take omeprazole and sodium bicarbonate?

• Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.

• Take this medication on an empty stomach, at least 1 hour till eating a meal. If this medication is given to a face who is fed through a nasogastric (NG) pipe, the feeding must be stopped at least 3 hours till giving the medication. Do not restart nasogastric feeding for at least 1 hour after giving omeprazole and sodium bicarbonate.

• Take the omeprazole and sodium bicarbonate capsule with a full glass of water. Do not use any another type of liquid or food.

• Do not open the capsule or empty the medication powder from it. Swallow the capsule whole.

• To use the powder form, open a packet and pour all of the powder into a little cup with 1 or 2 tablespoons of water. Do not use any another type of liquid. Stir the mixture and drink it right away. To create certain you get the entire doze, add a few more water to the same glass, swirl gently and drink right away.

• The 20-mg and the 40-mg forms of this medication contain the same power of sodium bicarbonate. Do not use two 20-mg capsules to equal one 40-mg capsule. Do not use two 20-mg powder packets to equal one 40-mg powder packet. If you do not use the exact capsule or powder packet your doctor has predesigned, you may receive too many sodium bicarbonate.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking omeprazole and sodium bicarbonate?

• Avoid taking this medication with milk if you use omeprazole and sodium bicarbonate long-term.

What are the possible side effects of omeprazole and sodium bicarbonate?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have:

· stiffness or loss of movement in any part of your body;

· diarrhea that is watery or bloody;

· quick or slow heartbeats;

· seizure (convulsions); or

· low magnesium (dizziness, confusion, quick or uneven heart course, jerking muscle movements, jittery feeling, muscle cramps, muscle weakness or limp feeling, cough or choking feeling).

• General side effects may include:

· headache;

· nausea, stomach pain, gas; or

· mild diarrhea.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect omeprazole and sodium bicarbonate?

• Omeprazole and sodium bicarbonate can change the way your body absorbs or eliminates determined another drugs. Speak your doctor about all medicines you use, and those you start or stop using during your treatment with omeprazole and sodium bicarbonate, especially:

· bosentan;

· citalopram;

· clopidogrel;

· cyclosporine;

· diazepam (Valium) or similar sedatives;

· digoxin, digitalis;

· disulfiram, Antabuse;

· methotrexate;

· rifabutin, rifampin, rifapentine;

· sodium polystyrene sulfonate;

· St. John's wort;

· tacrolimus;

· an antibiotic--ampicillin, clarithromycin, nafcillin, rifampin;

· an antifungal medicine--ketoconazole, voriconazole;

· a blood thinner such as warfarin, Coumadin;

· calcium supplements or iron supplements (including ferrous fumarate, ferrous gluconate, ferrous sulfonate);

· a diuretic or "water pill";

· HIV medicine--atazanavir, efavirenz, nelfinavir, nevirapine, rilpivirine, ritonavir, saquinavir; or

· seizure medication--carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, primidone.

• This list is not complete and another drugs may interact with omeprazole and sodium bicarbonate. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about omeprazole and sodium bicarbonate.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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