CHOLINE MAGNESIUM TRISALICYLATE

(KOE leen mag NEE see um TRYE sa LIS i late) Brand: Choline Magnesium Trisalicylate, Tricosal, Trilisate

What is the most significant information I must know about choline magnesium trisalicylate?

• This medication may reason life-threatening heart or circulation problems such as heart onslaught or stroke, especially if you use it long term. Do not use just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• Get abnormal medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

• This medication may also reason serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning, especially in older adults.

• Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

• This medicine must not be given to a baby or teenager who has a fever, especially if the baby also has flu symptoms or chicken pox. Salicylates can reason a serious and sometimes fatal condition called Reye's syndrome in children.

What is choline magnesium trisalicylate?

• Choline magnesium trisalicylate is a non-steroidal anti-inflammatory drug (NSAID) that contains a combination of choline salicylate and magnesium salicylate.

• Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medicine is also used to treat fever in adults.

• Choline magnesium trisalicylate may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking choline magnesium trisalicylate?

• This medication may reason life-threatening heart or circulation problems such as heart onslaught or stroke, especially if you use it long term. Do not use choline magnesium trisalicylate just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• You must not use this medicine if you are allergic to aspirin or to an NSAID, or if you have recently used cidofovir (Vistide), ketorolac (Toradol), or nasal flu vaccine (FluMist).

• To create certain you can safely take this medication, speak your doctor if you have any of these another conditions:

· heart malady, tall blood pressure, congestive heart failure, or a history of stroke or heart attack;

· a stomach ulcer or intestinal bleeding;

· a bleeding or blood clotting disorder;

· diabetes;

· anemia (a lack of red blood cells);

· liver or kidney disease;

· an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

· asthma, nasal polyps; or

· swelling or fluid retention, or if you are dehydrated.

• FDA pregnancy category C. Salicylates and NSAIDs may be deleterious to an unborn child if the mother takes the medicine during the recent 3 months of pregnancy. Speak your doctor if you are pregnant or plan to become pregnant.

• Choline magnesium trisalicylate can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Do not give to a baby or teenager who has a fever, especially if the baby also has flu symptoms or chicken pox. Salicylates can reason a serious and sometimes fatal condition called Reye's syndrome in children.

How must I take choline magnesium trisalicylate?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Take choline magnesium trisalicylate with food, milk, or an antacid if it upsets your stomach. You may need to take the medication at bedtime, at least 30 minutes till you lie down.

• Measure liquid medication with a particular dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. You may mix the liquid with a little amount of fruit juice to create the medication taste better. Stir the mixture well and drink all of it right away.

• It may take up to 3 weeks till your symptoms improve. Hold using the medicine as directed and speak your doctor if your symptoms do not improve after 2 weeks of treatment.

• This medicine can reason unusual results with determined medical trials. Speak any doctor who treats you that you are using choline magnesium trisalicylate.

• If you need surgery, speak the surgeon onward of time that you are using choline magnesium trisalicylate. You may need to stop using the medication for a short time.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include ringing in your ears, severe dizziness or drowsiness, confusion, or seizure (convulsions).

What must I avoid while taking choline magnesium trisalicylate?

• If you also take an antibiotic, avoid taking it within 2 hours till or after you take choline magnesium trisalicylate. This medicine can create it harder for your body to absorb determined antibiotics.

• If you are also taking low-dose aspirin to prevent heart onslaught or stroke, do not stop taking it or change your doze without your doctor's advice. Aspirin must be used for cardiovascular conditions only under the supervision of a doctor.

• Ask a doctor or pharmacist till using any cool, allergy, or pain medication. Much medicines accessible over the counter contain salicylates or NSAIDs. Taking determined commodity together can reason you to get too many of a determined drug. Check the label to see if a medication contains aspirin, ibuprofen, ketoprofen, naproxen, or a salicylate.

• Drinking alcohol may magnify your risk of stomach bleeding.

• Smoking can also magnify your risk of stomach bleeding.

What are the possible side effects of choline magnesium trisalicylate?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Stop using choline magnesium trisalicylate and call your doctor at once if you have a serious side effect such as:

· chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;

· sudden numbness or weakness, especially on one side of the body;

· bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

· blood in your urine, urinating more or smaller than usual;

· hearing problems, ringing in your ears;

· severe stomach pain, ongoing nausea or vomiting, jaundice (yellowing of the skin or eyes);

· light bruising or bleeding, unusual weakness; or

· quick or pounding heartbeats, feeling like you might pass out.

• Smaller serious side effects may include:

· heartburn, upset stomach, diarrhea, constipation;

· dizziness, drowsiness, lack of energy; or

· headache.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect choline magnesium trisalicylate?

• Ask your doctor till taking an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). Taking any of these drugs with an NSAID may reason you to bruise or bleed easily.

• Much drugs can interact with choline magnesium trisalicylate. Adown is just a partial list. Speak your doctor if you are using:

· cyclosporine (Gengraf, Neoral, Sandimmune);

· lithium (Eskalith, LithoBid);

· methotrexate (Rheumatrex, Trexall);

· a blood thinner such as warfarin (Coumadin), or medicine used to prevent blood clots, such as clopidogrel (Plavix);

· diabetes medicine you take by mouth;

· a diuretic (water pill);

· heart or blood pressure medication;

· medication to treat or prevent osteoporosis;

· seizure medicine such as phenytoin (Dilantin), phenobarbital (Solfoton), or valproic acid (Depakene);

· medicines that contain sodium bicarbonate, sodium citrate, or potassium citrate; or

· steroid medication (prednisone and others).

• This list is not complete and there are much another drugs that can interact with choline magnesium trisalicylate. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor. Hold a list of all your medicines and show it to any healthcare provider who treats you.

Where can I get more information?

• Your pharmacist can provide more information about choline magnesium trisalicylate.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.