ACETAMINOPHEN, DEXTROMETHORPHAN, AND DOXYLAMINE

(a SEET a MIN oh fen, DEX tro me THOR fan, and dox IL a meen) Brand: All-Nite, Contac Cold+Flu Cooling Night, Coricidin HBP Nighttime Multi-Symptom Cool, Cough & Sore Throat Nighttime, Delsym Nighttime Cough & Cool, Multi-Symptom Nighttime Cool & Flu Relief, Multi-Symptom Nighttime Cool & Flu Relief (cherry), Night Time Cold/Flu, Nite Time Cool & Flu, Nyquil Cool & Flu, Nyquil Cool & Flu Nighttime, NyQuil Cold/Flu Relief, NyQuil Cold/Flu Relief Cherry, NyQuil Character Fusion Cool & Flu Nighttime, Robitussin Peak Cool Nighttime Cool + Flu, Sunmark Nite Time Cool and Flu, Tylenol Cool & Cough Nighttime Cold Burst, Tylenol Cough & Sore Throat Night Time, Tylenol Warming Cough & Sore Throat Nightime

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What is the most significant information I must know about this medicine?

Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

• Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

• In rare cases, acetaminophen may reason a severe skin reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

What is acetaminophen, dextromethorphan, and doxylamine?

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.

Doxylamine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can manufacture symptoms of sneezing, itching, watery eyes, and runny nose.

Acetaminophen, dextromethorphan, and doxylamine is a combination medication used to treat headache, fever, body aches, cough, runny nose, sneezing, and sore throat caused by allergies, the general cool, or the flu.

• This medication will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, dextromethorphan, and doxylamine may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking this medicine?

Ask a doctor till taking medication that contains acetaminophen if you have ever had liver malady, or if you drink more than 3 alcoholic beverages for day.

Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

• You must not use this medicine if you are allergic to acetaminophen (Tylenol), doxylamine, or dextromethorphan.

• Ask a doctor or pharmacist till taking this medication if you have any medical condition, especially:

· asthma or COPD, cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;

· a blockage in your stomach or intestines;

· liver malady, alcoholism, or if you drink more than 3 alcoholic beverages for day;

· kidney disease;

· an enlarged prostate, problems with urination;

· glaucoma; or

· if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

• It is not known whether this medication will harm an unborn child. Do not use cough and cool medication without a doctor's advice if you are pregnant.

• This medication may pass into breast milk and may harm a nursing child. Antihistamines may also slow breast milk manufacture. Do not use cough and cool medication without a doctor's advice if you are breast-feeding a baby.

• Artificially sweetened liquid medication may contain phenylalanine. Check the medicine label if you have phenylketonuria (PKU).

Always ask a doctor till giving a cough or cool medication to a baby. Death can occur from the misuse of cough and cool medicines in very young children.

How must I take acetaminophen, dextromethorphan, and doxylamine?

• Use exactly as directed on the label, or as predesigned by your doctor. Do not use for longer than recommended. Cough and cool medication is generally taken only for a short time before your symptoms clear up.

• Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death.

• Measure liquid medication with a particular dose-measuring spoon or medication cup. If you do not have a dose-measuring device, ask your pharmacist for one.

• Stop taking the medication and call your doctor if you still have a sore throat after 2 days, or if you have a fever, headache, rash, nausea, or vomiting.

• If you need surgery or medical trials, speak the surgeon or doctor onward of time if you have taken this medication within the past little days.

• Store at room temperature away from moisture and heat. Do not let liquid medication to freeze.

What happens if I miss a dose?

• Since this medication is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.

• The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

What must I avoid while taking this medicine?

• Ask a doctor or pharmacist till using any another cool, allergy, pain, or sleep medicine. Acetaminophen (sometimes abbreviated as APAP) is contained in much combination medicines. Taking determined commodity together can reason you to get too many acetaminophen which can lead to a fatal overdose. Check the label to see if a medication contains acetaminophen or APAP.

• Avoid drinking alcohol. It may magnify your risk of liver hurt while you are taking acetaminophen, and can magnify determined side effects.

• This medicine may reason blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

What are the possible side effects of this medicine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

In rare cases, acetaminophen may reason a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you must never again take any medication that contains acetaminophen.

• Stop using the medication and call your doctor at once if you have:

· severe headache, seizure (convulsions);

· quick, pounding, or uneven heartbeats;

· confusion, hallucinations, severe dizziness or drowsiness, slow or shallow breathing;

· tremor, restless muscle movements;

· few or no urinating;

· flu symptoms, light bruising, unusual bleeding, pale skin, weakness, feeling light-headed; or

· nausea, pain in your upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

• General side effects may include:

· headache, sleep problems (insomnia);

· upset stomach, diarrhea or constipation;

· dry eyes, blurred vision, dry mouth or nose;

· mild dizziness or drowsiness, trouble concentrating;

· feeling restless or excited (especially in children); or

· mild skin rash.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect acetaminophen, dextromethorphan, and doxylamine?

• Ask a doctor or pharmacist till using this medication if you are also using any another drugs, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Some medicines can reason unwanted or dangerous effects when used together. Not all possible interactions are listed in this medicine manual.

• Taking this medication with another drugs that create you sleepy or slow your breathing can worsen these effects. Ask your doctor till taking acetaminophen, dextromethorphan, and doxylamine with a sleeping pill, narcotic pain medication, muscle relaxer, or medication for anxiety, depression, or seizures.

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen, dextromethorphan, and doxylamine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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