TRIHEXYPHENIDYL

(try hex ee FEH nih dill) Brand: Artane, Trihexane

What is the most significant information I must know about trihexyphenidyl?

• Use caution when driving, operating machinery, or performing another hazardous activities. Trihexyphenidyl may reason dizziness or blurred vision. If you experience dizziness or blurred vision, avoid these activities.

• Use alcohol cautiously. Alcohol may magnify drowsiness and dizziness while taking trihexyphenidyl.

• Avoid becoming overheated. Trihexyphenidyl may reason decreased sweating. This could lead to heat stroke in hot weather or with vigorous exercise.

What is trihexyphenidyl?

• Trihexyphenidyl alters unusual nerve impulses and relaxes stiff muscles.

• Trihexyphenidyl is used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's malady. It is also used to treat and prevent the same muscular conditions when they are caused by drugs such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), haloperidol (Haldol), thiothixene (Navane), and others.

• Trihexyphenidyl may also be used for purposes another than those listed in this medicine guide.

What must I discuss with my healthcare provider till taking trihexyphenidyl?

• Do not use trihexyphenidyl without first talking to your doctor if you have

· ever had an allergic reaction to it;

· narrow-angle glaucoma;

· an obstruction in the bowel or a complication of bowel malady known as megacolon; or

· myasthenia gravis.

• Till taking this medicine, speak your doctor if you have

· enlargement of the prostate or difficulty urinating;

· epilepsy or other seizure disorder;

· heart malady or an irregular heartbeat;

· depression or any another psychiatric illness;

· kidney malady; or

· liver disease.

• You may require a dosage adjustment or particular monitoring during treatment if you have any of the conditions listed above.

• It is not known whether trihexyphenidyl will be deleterious to an unborn child. Do not take this medicine without first talking to your doctor if you are pregnant or could become pregnant during treatment.

• It is not known whether trihexyphenidyl passes into breast milk. Do not take this medicine without first talking to your doctor if you are breast-feeding a baby.

How must I take trihexyphenidyl?

• Take trihexyphenidyl exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

• Take every doze with a full glass of water.

• Trihexyphenidyl may be taken with or without meals. Taking trihexyphenidyl with food may lessen stomach upset.

• To ensure that you get a correct doze, measure the liquid form of trihexyphenidyl with a particular dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

• Store trihexyphenidyl at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. However, if it is nearly time for the following doze, skip the missed doze and only take the following regularly scheduled doze. Do not take a double doze of this medication.

What happens if I overdose?

• Search abnormal medical attention.

• Symptoms of a trihexyphenidyl overdose include big pupils; warm, dry skin; flushed person; fever; dry mouth; quick or irregular heartbeat; anxiety; hallucinations; confusion; agitation; hyperactivity; loss of consciousness; and seizures.

What must I avoid while taking trihexyphenidyl?

• Use caution when driving, operating machinery, or performing another hazardous activities. Trihexyphenidyl may reason dizziness or blurred vision. If you experience dizziness or blurred vision, avoid these activities.

• Use alcohol cautiously. Alcohol may magnify drowsiness and dizziness while taking trihexyphenidyl.

• Avoid becoming overheated. Trihexyphenidyl may reason decreased sweating. This could lead to heat stroke in hot weather or with vigorous exercice. Try to hold as cold as possible and watch for signs of heat stroke such as decreased sweating, nausea, and dizziness.

What are the possible side effects of trihexyphenidyl?

• If you experience any of the next serious side effects, stop taking trihexyphenidyl and search abnormal medical attention or contact your doctor immediately:

· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or person; or hives);

· fever;

· quick or irregular heartbeats;

· anxiety, hallucinations, confusion, agitation, hyperactivity, or loss of consciousness;

· seizures;

· eye pain; or

· a rash.

• Another, smaller serious side effects may be more likely to occur. Continue to take trihexyphenidyl and conversation to your doctor if you experience

· dryness of the mouth;

· big pupils or blurred vision;

· drowsiness or dizziness;

· difficulty urinating or constipation;

· nervousness or anxiety;

· upset stomach; or

· decreased sweating.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect trihexyphenidyl?

• Till taking this medicine, speak your doctor if you are taking any of the next medicines:

· a tricyclic antidepressant (used to treat depression, pain, or obsessive-compulsive disorder) such as amitriptyline (Elavil, Endep), doxepin (Sinequan), clomipramine (Anafranil), amoxapine (Asendin), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), or protriptyline (Vivactil);

· a phenothiazine (used to treat mania, schizophrenia, another psychiatric conditions, and nausea and vomiting) such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), thioridazine (Mellaril), promazine (Sparine), trifluoperazine (Stelazine), and others;

· thiothixene (Navane) or chlorprothixene (Taractan);

· an antihistamine such as diphenhydramine (Benadryl, others), chlorpheniramine (Chlor-Trimeton, others), triprolidine (Actifed, others), brompheniramine (Dimetapp, others), clemastine (Tavist), and others (antihistamines are often found in prescription and over-the-counter cool, allergy, and sleep medicines);

· quinidine (Quinora, Quinaglute, Quinidex, Cardioquin);

· amantadine (Symmetrel);

· digoxin (Lanoxin, Lanoxicaps); or

· haloperidol (Haldol).

• You may not be able to take trihexyphenidyl or you may require a dosage adjustment or particular monitoring if you are taking any of the medicines listed above.

• Drugs another than those listed here may also interact with trihexyphenidyl. Conversation to your doctor and pharmacist till taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

• Your pharmacist has more information about trihexyphenidyl written for health professionals that you may read.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.