HYDROCHLOROTHIAZIDE AND BENAZEPRIL

(HYE droe KLOR oh THY a zide and ben AZ e pril) Brand: Lotensin HCT

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What is the most significant information I must know about hydrochlorothiazide and benazepril?

Do not use hydrochlorothiazide and benazepril if you are pregnant. Stop using this medicine and speak your doctor right away if you become pregnant.

• You must not use this medicine if you are allergic to hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic) or benazepril (Lotensin), or if you have ever had angioedema (hives or severe swelling of deep skin tissues sometimes caused by allergic reaction).

• You must not use this medicine if you are allergic to any another ACE inhibitor, such as captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

• Till taking hydrochlorothiazide and benazepril, speak your doctor if you have kidney malady (or are on dialysis), liver malady, glaucoma, congestive heart failure, lupus, diabetes, or an allergy to sulfa drugs or penicillin.

• Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking hydrochlorothiazide and benazepril, unless your doctor has told you to.

• Some things can reason your blood pressure to get too low. This includes vomiting, diarrhea, hard sweating, heart malady, dialysis, a low-salt diet, or taking another diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you must drink while taking hydrochlorothiazide and benazepril. Speak your doctor if you have a prolonged diseases that causes diarrhea or vomiting.

What is hydrochlorothiazide and benazepril?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too many salt, which can reason fluid retention.

Benazepril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Benazepril lowers blood pressure and also relieves symptoms of fluid retention.

• The combination of hydrochlorothiazide and benazepril is used to treat hypertension (high blood pressure).

Hydrochlorothiazide and benazepril may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking hydrochlorothiazide and benazepril?

• You must not use this medicine if you are allergic to hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic) or benazepril (Lotensin), or if you have ever had angioedema (hives or severe swelling of deep skin tissues sometimes caused by allergic reaction).

• You must not use this medicine if you are allergic to another ACE inhibitor, such as captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

• To create certain you can safely take hydrochlorothiazide and benazepril, speak your doctor if you have any of these another conditions:

· kidney malady (or if you are on dialysis);

· liver disease;

· glaucoma;

· congestive heart failure;

· lupus;

· diabetes;

· an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or

· an allergy to sulfa drugs or penicillin.

• FDA pregnancy category D. Do not use hydrochlorothiazide and benazepril if you are pregnant. Stop using this medicine and speak your doctor right away if you become pregnant. Hydrochlorothiazide and benazepril can reason injury or death to the unborn child if you take the medication during your second or third trimester. Use effective birth control while taking hydrochlorothiazide and benazepril.

Hydrochlorothiazide can pass into breast milk and may harm a nursing child. You must not breast-feed while you are using hydrochlorothiazide and benazepril.

How must I take hydrochlorothiazide and benazepril?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Your doctor may occasionally change your doze to create certain you get the excellent results.

• Conditions that may reason very low blood pressure include: vomiting, diarrhea, hard sweating, heart malady, dialysis, a low salt diet, or taking diuretics (water pills). Speak your doctor if you have a prolonged diseases that causes diarrhea or vomiting.

• Your blood pressure will need to be checked often. Your kidney function may also need to be checked. Your blood and urine may also be tested if you have been vomiting or are dehydrated. Visit your doctor regularly.

• If you need surgery or medical trials, speak the doctor onward of time that you are taking medicine that contains hydrochlorothiazide. You may need to stop using the medication for a short time.

• Hold using this medication as directed, even if you feel well. Tall blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

• Store at room temperature away from moisture and heat. Hold the tablets in their original container, along with the packet of moisture-absorbing preservative that comes with this medication.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include dizziness or feeling like you might pass out.

What must I avoid while taking hydrochlorothiazide and benazepril?

• Avoid becoming overheated or dehydrated during exercice and in hot weather. Follow your doctor's instructions about the type and amount of liquids you must drink. In some cases, drinking too many liquid can be as unsafe as not drinking enough.

• Avoid getting up too quick from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

• Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking hydrochlorothiazide and benazepril, unless your doctor has told you to.

What are the possible side effects of hydrochlorothiazide and benazepril?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop taking this medicine and call your doctor at once if you have any of these serious side effects:

· eye pain, vision problems;

· tall potassium (slow heart course, weak pulse, muscle weakness, tingly feeling);

· urinating smaller than normal or not at all;

· weakness, confusion, heighten thirst, loss of appetite, vomiting, pounding heartbeats or fluttering in your chest;

· swelling, weight gain, feeling short of breath;

· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

· pale or yellowed skin, dark colored urine, fever, jaundice (yellowing of the skin or eyes);

· wheezing, trouble breathing; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· cough;

· headache;

· dizziness, drowsiness, weary feeling;

· nausea, constipation, upset stomach; or

· mild skin rash, heighten sweating.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect hydrochlorothiazide and benazepril?

• Speak your doctor about all another medicines you use, especially:

· another diuretics (water pills) or blood pressure medications;

· gold injections for arthritis;

· lithium (Lithobid, Eskalith);

· a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others; or

· insulin or oral diabetes medication.

• This list is not complete and another drugs may interact with hydrochlorothiazide and benazepril. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about hydrochlorothiazide and benazepril.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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