CHLORPHENIRAMINE AND DEXTROMETHORPHAN

(klor feh NEER a meen and DEX troe meh THOR fan) Brand: Children's NyQuil Cool & Cough, Coricidin HBP Cough & Cool, Dimetapp Long Acting Cough Plus Cool, Robitussin Pediatric Cough & Cool Long-Acting, Triaminic Cough & Runny Nose, Tricodene Sugar Free

What is the most significant information I must know about chlorpheniramine and dextromethorphan?

• Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

What is chlorpheniramine and dextromethorphan?

• Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can manufacture symptoms of sneezing, itching, watery eyes, and runny nose.

• Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

• Chlorpheniramine and dextromethorphan is a combination medication used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and cough caused by allergies, the general cool, or the flu.

• Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

• Chlorpheniramine and dextromethorphan may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking chlorpheniramine and dextromethorphan?

• Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

• Ask a doctor or pharmacist if it is safety for you to take this medication if you have another medical conditions, especially:

· asthma or COPD, cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;

· a blockage in your stomach or intestines;

· glaucoma;

· kidney disease;

· liver disease;

· diabetes;

· heart malady or tall blood pressure;

· a thyroid disorder;

· cough with mucus, or cough caused by emphysema or chronic bronchitis;

· enlarged prostate or urination problems; or

· if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

• It is not known whether chlorpheniramine and dextromethorphan will harm an unborn child. Do not use this medication without your doctor's advice if you are pregnant.

• This medicine may pass into breast milk and may harm a nursing child. Antihistamines may also slow breast milk manufacture. Do not use this medication without your doctor's advice if you are breast-feeding a baby.

• Artificially sweetened liquid medication may contain phenylalanine. Check the medicine label if you have phenylketonuria (PKU).

How must I take chlorpheniramine and dextromethorphan?

• Use exactly as directed on the label, or as predesigned by your doctor. Do not use in larger or less amounts or for longer than recommended. Cough or cool medication is generally taken only for a short time before your symptoms clear up.

• Do not give this medicine to a baby younger than 4 years old. Always ask a doctor till giving a cough or cool medication to a child. Death can occur from the misuse of cough and cool medicines in very young children.

• Measure liquid medication with a particular dose-measuring spoon or medication cup. If you do not have a dose-measuring device, ask your pharmacist for one.

• The chewable tablet should be chewed till you swallow it.

• Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

• If you need surgery or medical trials, speak the surgeon or doctor onward of time if you have taken this medication within the past little days.

• Store at room temperature away from moisture and heat. Do not let liquid medication to freeze.

What happens if I miss a dose?

• Since this medication is taken when needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking chlorpheniramine and dextromethorphan?

• Ask a doctor or pharmacist till using any another cool, allergy, or sleep medicine. Chlorpheniramine and dextromethorphan are contained in much combination medicines. Taking determined commodity together can reason you to get too many of a determined medication. Check the label to see if a medication contains an antihistamine or cough suppressant (antitussive).

• This medication may reason blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

• Drinking alcohol can magnify determined side effects of chlorpheniramine.

What are the possible side effects of chlorpheniramine and dextromethorphan?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Stop using this medication and call your doctor at once if you have:

· quick, slow, or uneven heart rate;

· severe dizziness or anxiety, feeling like you might pass out;

· mood changes, severe headache;

· fever;

· tremor, seizure (convulsions);

· few or no urinating; or

· light bruising or bleeding, unusual weakness.

• General side effects may include:

· mild dizziness, drowsiness;

· dry mouth, nose, or throat;

· constipation, diarrhea;

· blurred vision; or

· feeling nervous, restless, or irritable.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect chlorpheniramine and dextromethorphan?

• Ask a doctor or pharmacist till using this medication if you are also using any another drugs, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Some medicines can reason unwanted or dangerous effects when used together. Not all possible interactions are listed in this medicine manual.

• Taking this medication with another drugs that create you sleepy or slow your breathing can worsen these effects. Ask your doctor till taking chlorpheniramine and dextromethorphan with a sleeping pill, narcotic pain medication, muscle relaxer, or medication for anxiety, depression, or seizures.

Where can I get more information?

• Your pharmacist can provide more information about chlorpheniramine and dextromethorphan.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.