ACETAMINOPHEN, DICHLORALPHENAZONE, AND ISOMETHEPTENE

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What is the most significant information I must know about this medicine?

• You must not take this medication if you have liver malady, severe kidney malady, glaucoma, tall blood pressure, heart malady, coronary artery malady, circulation problems, peripheral vascular malady, or if you have recently had a stroke or heart attack.

• To create certain this medication is safety for you, tell your doctor if you have ever had alcoholic liver malady (cirrhosis) or if you drink more than 3 alcoholic beverages for day.

Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

• Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

• In rare cases, acetaminophen may reason a severe skin reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

What is acetaminophen, dichloralphenazone, and isometheptene?

Acetaminophen is a pain reliever and a fever reducer.

• Dichloralphenazone is a sedative that slows the central nervous system.

• Isometheptene causes narrowing of blood vessels (vasoconstriction).

Acetaminophen, dichloralphenazone, and isometheptene is a combination medication used to treat migraine headaches or severe tension headaches.

Acetaminophen, dichloralphenazone, and isometheptene may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking this medicine?

Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

• Speak your doctor if you have ever had alcoholic liver malady (cirrhosis) or if you drink more than 3 alcoholic beverages for day. You may not be able to take medication that contains acetaminophen.

• You must not take this medication if you are allergic to acetaminophen (Tylenol), dichloralphenazone, isometheptene, or chloral hydrate (Somnote), or if you have:

· liver disease;

· severe kidney disease;

· glaucoma;

· peripheral vascular malady such as Raynaud's syndrome;

· tall blood pressure, heart malady, coronary artery malady, blood circulation problems; or

· if you have recently had a stroke or heart attack.

• To create certain acetaminophen, dichloralphenazone, and isometheptene is safety for you, speak your doctor if you have a history of kidney disease.

• It is not known whether this medication will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

Acetaminophen, dichloralphenazone, and isometheptene can pass into breast milk and may harm a nursing child. Speak your doctor if you are breast-feeding a baby.

How must I take this medicine?

• Follow all directions on your prescription label. Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death.

• You may take this medicine with or without food.

• To treat migraine headache pain:

· Take the first doze of this medicine as soon as you announcement headache symptoms, or after an onslaught has already begun.

· If your headache does not completely go away, take 1 capsule each hour before you feel relief.

· Do not take more than a total of 5 capsules in any 12-hour period to treat a migraine.

· If you still have migraine symptoms after taking a total of 5 capsules, call your doctor.

• To treat tension headache pain:

· Take the first doze of this medicine as soon as you announcement tension headache symptoms.

· If your headache does not completely go away, take 1 capsule each 4 hours before you feel relief.

· Do not take more than a total of 8 capsules in any 24-hour period to treat a tension headache.

· If you still have tension headache pain after taking a total of 8 capsules, call your doctor.

• Call your doctor if this medicine seems to stop working as well in relieving your pain. Also call your doctor if your headaches get worse or you have more than 2 headaches for week.

• Do not stop using this medication suddenly if you have been using it for longer than 2 weeks in a row, or you could have unpleasant withdrawal symptoms. Conversation to your doctor about how to avoid withdrawal symptoms when you stop using acetaminophen, dichloralphenazone, and isometheptene.

• This medicine can reason unusual results with determined medical trials. Speak any doctor who treats you that you are using acetaminophen, dichloralphenazone, and isometheptene.

• Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

• Since this medication is used as needed, it does not have a daily dosing schedule. Call your doctor promptly if your symptoms do not improve after using acetaminophen, dichloralphenazone, and isometheptene.

Do not take more than 5 capsules in 12 hours to treat a migraine, or 8 capsules in 24 hours to treat a tension headache.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can hurt your liver or reason death.

• The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

What must I avoid while taking this medicine?

• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Avoid drinking alcohol. It may magnify your risk of liver hurt while taking acetaminophen.

• Ask a doctor or pharmacist till using any another pain, cool, allergy, or sleep medicine. Acetaminophen (sometimes abbreviated as APAP) is contained in much combination medicines. Taking determined commodity together can reason you to get too many acetaminophen which can lead to a fatal overdose. Check the label to see if a medication contains acetaminophen or APAP.

What are the possible side effects of this medicine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

In rare cases, acetaminophen may reason a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you must never again take any medication that contains acetaminophen.

• Stop using this medication and call your doctor at once if you have:

· severe drowsiness or restless feeling, feeling like you might pass out;

· quick, slow, or uneven heart rate;

· rapid breathing, weak or shallow breathing;

· few or no urinating;

· cool feeling; or

· liver problems--nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

• General side effects may include:

· dizziness, drowsiness; or

· upset stomach.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect this medicine?

• Taking this medication with another drugs that create you sleepy or slow your breathing can worsen these effects. Ask your doctor till taking acetaminophen, dichloralphenazone, and isometheptene with a sleeping pill (especially sodium oxybate), narcotic pain medication, muscle relaxer, or medication for anxiety, depression, mental diseases, or seizures.

• Another drugs may interact with acetaminophen, dichloralphenazone, and isometheptene, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen, dichloralphenazone, and isometheptene.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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