ACETAMINOPHEN, CHLORPHENIRAMINE, AND PHENYLEPHRINE

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What is the most significant information I must know about acetaminophen, chlorpheniramine, and phenylephrine?

Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

• Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

• In rare cases, acetaminophen may reason a severe skin reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

What is acetaminophen, chlorpheniramine, and phenylephrine?

Acetaminophen is a pain reliever and fever reducer.

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can manufacture symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can reason nasal congestion (stuffy nose).

Acetaminophen, chlorpheniramine, and phenylephrine is a combination medication used to treat headache, fever, body aches, runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the general cool, or the flu.

Acetaminophen, chlorpheniramine, and phenylephrine may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking this medicine?

• You must not use this medicine if you are allergic to acetaminophen, chlorpheniramine, or phenylephrine.

Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

• Ask a doctor or pharmacist if it is safety for you to take this medication if you have another medical conditions, especially:

· asthma or COPD, cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;

· a blockage in your stomach or intestines;

· liver malady, alcoholism, or if you drink more than 3 alcoholic beverages for day;

· kidney disease;

· tall blood pressure, heart malady, coronary artery malady, or last heart attack;

· enlarged prostate or urination problems;

· glaucoma;

· diabetes;

· overactive thyroid;

· pheochromocytoma (an adrenal gland tumor); or

· if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

• It is not known whether acetaminophen, chlorpheniramine, and phenylephrine will harm an unborn child. Do not use this medication without your doctor's advice if you are pregnant.

• This medicine may pass into breast milk and may harm a nursing child. Antihistamines and decongestants may also slow breast milk manufacture. Do not use this medication without your doctor's advice if you are breast-feeding a baby.

How must I take this medicine?

• Use exactly as directed on the label, or as predesigned by your doctor. Do not use in larger or less amounts or for longer than recommended. This medication is generally taken only for a short time before your symptoms clear up.

• Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death.

• Measure liquid medication with a particular dose-measuring spoon or medication cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

• Drop the effervescent tablets into a glass of water (at least 4 ounces, or one-half cup). Stir this mixture and drink all of it right away.

• Do not give this medicine to a baby younger than 4 years old. Always ask a doctor till giving a cough or cool medication to a child. Death can occur from the misuse of cough and cool medicines in very young children.

Do not take for longer than 7 days in a row. Stop taking the medication and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days (or 5 days if treating a child), if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.

• If you need surgery or medical trials, speak the surgeon or doctor onward of time if you have taken this medication within the past little days.

• Store at room temperature away from moisture and heat. Do not let liquid medication to freeze.

What happens if I miss a dose?

• Since this medication is taken when needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1 800 222 1222. An overdose of acetaminophen can be fatal.

• The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

What must I avoid while taking this medicine?

• Ask a doctor or pharmacist till using any another cool, allergy, pain, or sleep medicine. Acetaminophen (sometimes abbreviated as APAP) is contained in much combination medicines. Taking determined commodity together can reason you to get too many acetaminophen which can lead to a fatal overdose. Check the label to see if a medication contains acetaminophen or APAP.

• Avoid drinking alcohol. It may magnify your risk of liver hurt while taking acetaminophen, and can magnify determined side effects of chlorpheniramine.

• This medication may reason blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

What are the possible side effects of acetaminophen, chlorpheniramine, and phenylephrine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

In rare cases, acetaminophen may reason a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you must never again take any medication that contains acetaminophen.

• Stop using this medication and call your doctor at once if you have:

· chest pain, rapid pulse, quick or uneven heart rate;

· confusion, hallucinations, severe nervousness;

· tremor, seizure (convulsions);

· light bruising or bleeding, unusual weakness;

· few or no urinating;

· nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes); or

· dangerously tall blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, shortness of breath, uneven heartbeats, seizure).

• General side effects may include:

· dizziness, drowsiness;

· mild headache, blurred vision;

· dry mouth, nose, or throat;

· constipation;

· feeling nervous; or

· sleep problems (insomnia);

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect acetaminophen, chlorpheniramine, and phenylephrine?

• Ask a doctor or pharmacist till using this medication if you are also using any another drugs, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Some medicines can reason unwanted or dangerous effects when used together. Not all possible interactions are listed in this medicine manual.

• Taking this medication with another drugs that create you sleepy or slow your breathing can worsen these effects. Ask your doctor till taking acetaminophen, chlorpheniramine, and phenylephrine with a sleeping pill, narcotic pain medication, muscle relaxer, or medication for anxiety, depression, or seizures.

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen, chlorpheniramine, and phenylephrine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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