ACETAMINOPHEN AND PHENYLEPHRINE

(a SEET a MIN oh fen and FEN il EFF rin) Brand: Alka-Seltzer Plus Cool and Sinus, Contac Cold+Flu Non-Drowsy, Excedrin Sinus Headache Caplet, Mapap Sinus Congestion and Pain, Robitussin Nasal Relief, Sinus Congestion and Pain Daytime Cold Ice, Sinus Pain & Pressure, Sudafed PE Pressure+Pain, Sudafed PE Sinus Headache, Theraflu Daytime Severe Cool, Tylenol Sinus Congestion and Pain

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What is the most significant information I must know about acetaminophen and phenylephrine?

Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

• Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

• In rare cases, acetaminophen may reason a severe skin reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

What is acetaminophen and phenylephrine?

Acetaminophen is a pain reliever and a fever reducer.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can reason nasal congestion (stuffy nose).

Acetaminophen and phenylephrine is a combination medication used to treat headache, fever, body aches, stuffy nose, and sinus congestion caused by allergies, the general cool, or the flu.

Acetaminophen and phenylephrine may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking acetaminophen and phenylephrine?

• You must not use this medication if you are allergic to acetaminophen (Tylenol) or phenylephrine.

Do not use this medication if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

• Ask a doctor or pharmacist if it is safety for you to take this medication if you have another medical conditions, especially:

· liver malady, cirrhosis, a history of alcoholism, or if you drink more than 3 alcoholic beverages for day;

· tall blood pressure, heart malady, coronary artery disease;

· overactive thyroid;

· pheochromocytoma (an adrenal gland tumor); or

· if you take an anti-depressant.

• It is not known whether acetaminophen and phenylephrine will harm an unborn child. Do not use cough or cool medication without a doctor's advice if you are pregnant.

Acetaminophen and phenylephrine may pass into breast milk and may harm a nursing child. Decongestants may also slow breast milk manufacture. Do not use cough or cool medication without a doctor's advice if you are pregnant.

Always ask a doctor till giving a cough or cool medication to a child. Death can occur from the misuse of cough and cool medicines in very young children.

How must I take acetaminophen and phenylephrine?

• Use exactly as directed on the label, or as predesigned by your doctor. Do not use for longer than recommended. Cool medication is generally taken only for a short time before your symptoms clear up.

• Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death.

• Dissolve one packet of the powder in at least 4 ounces of water. Stir this mixture and drink all of it right away.

• Drop the effervescent tablets into a glass of water (at least 4 ounces, or one-half cup). Stir this mixture and drink all of it right away.

• Stop taking the medication and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days (or 5 days if treating a child), if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.

• If you need surgery or medical trials, speak the surgeon or doctor onward of time if you have taken this medication within the past little days.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Since this medication is taken when needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.

• The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

What must I avoid while taking acetaminophen and phenylephrine?

• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Ask a doctor or pharmacist till using any another cool, allergy, pain, or sleep medicine. Acetaminophen (sometimes abbreviated as APAP) is contained in much combination medicines. Taking determined commodity together can reason you to get too many acetaminophen which can lead to a fatal overdose. Check the label to see if a medication contains acetaminophen or APAP.

• Avoid drinking alcohol. It may magnify your risk of liver hurt while taking acetaminophen.

What are the possible side effects of acetaminophen and phenylephrine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

In rare cases, acetaminophen may reason a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you must never again take any medication that contains acetaminophen.

• Stop using the medication and call your doctor at once if you have:

· quick, slow, or uneven heart course;

· confusion, hallucinations;

· tremor, seizure (convulsions);

· few or no urinating;

· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

· dangerously tall blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, seizure).

• General side effects may include:

· dizziness, weakness;

· mild headache;

· mild nausea, diarrhea, upset stomach;

· runny nose;

· feeling nervous, restless, or anxious; or

· sleep problems (insomnia).

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect acetaminophen and phenylephrine?

• Another drugs may interact with acetaminophen and phenylephrine, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen and phenylephrine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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