HYDROCODONE AND PHENYLEPHRINE

(high droe KOE dohn and fen ill EH frin) Brand: Lortuss HC, Nalex-DH

What is the most significant information I must know about hydrocodone and phenylephrine?

• Use caution when driving, operating machinery, or performing another hazardous activities. Hydrocodone and phenylephrine may reason dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

• Use alcohol cautiously. Alcohol may magnify drowsiness and dizziness while taking hydrocodone and phenylephrine.

• Hydrocodone and phenylephrine may magnify the effects of another drugs that reason drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Speak your doctor about all medicines that you are taking, and do not take any another medication without first talking to your doctor.

• Hydrocodone is habit forming. It is possible become physically and/or psychologically dependent on the medicine. Do not take more than the predesigned amount of medicine or take it for longer than is directed by your doctor. Withdrawal effects may occur if hydrocodone and phenylephrine is stopped suddenly after different weeks of continuous use. Your doctor may recommend a gradual abbreviation in dose.

What is hydrocodone and phenylephrine?

• Hydrocodone is a narcotic. It is a pain reliever and a cough suppressant.

• Phenylephrine is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in the body. Constriction of blood vessels in the sinuses and nose decreases congestion.

• Hydrocodone and phenylephrine is used to treat cough and nasal congestion associated with the general cool, sinus infections, the flu, and bronchitis.

• Hydrocodone and phenylephrine may also be used for purposes another than those listed in this medicine guide.

What must I discuss with my healthcare provider till taking hydrocodone and phenylephrine?

• Do not take hydrocodone and phenylephrine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), or selegiline (Eldepryl) in the recent 14 days. A dangerous drug interaction could occur, leading to serious side effects.

• Till taking hydrocodone and phenylephrine, speak your doctor if you have

· epilepsy or other seizure disorder;

· been diagnosed with sleep apnea (periods of not breathing during sleep);

· thyroid problems;

· asthma;

· a head injury;

· Addison's disease;

· diabetes;

· glaucoma;

· bladder problems or difficulty urinating;

· an enlarged prostate;

· tall blood pressure, irregular heartbeats, or any type of heart disease;

· kidney problems; or

· liver problems.

• You may not be able to take hydrocodone and phenylephrine, or you may require a dosage adjustment or particular monitoring during treatment if you have any of the conditions listed above.

• Hydrocodone and phenylephrine is in the FDA pregnancy category C. This means that it is not known whether hydrocodone and phenylephrine will be deleterious to an unborn child. Do not take hydrocodone and phenylephrine without first talking to your doctor if you are pregnant or could become pregnant during treatment.

• Hydrocodone and phenylephrine passes into breast milk and may be deleterious to a nursing child. Do not take hydrocodone and phenylephrine without first talking to your doctor if you are breast-feeding a baby.

• If you are over 65 years of age, you may be more likely to experience side effects from hydrocodone and phenylephrine. Your doctor may prescribe a lower doze of this medication.

How must I take hydrocodone and phenylephrine?

• Take hydrocodone and phenylephrine exactly as directed by your doctor. If you do not understand the directions on your prescription bottle, ask your pharmacist, nurse, or doctor to explain the instructions to you.

• Hydrocodone and phenylephrine can be taken with or without food.

• Take the oral tablets and capsules with a full glass of water.

• To ensure that you get a correct doze, measure the liquid form of hydrocodone and phenylephrine with a particular dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

• Do not take more of this medicine or take it for longer than is recommended. If your symptoms do not improve, or if they worsen, conversation to your doctor.

• Store hydrocodone and phenylephrine at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. However, if it is nearly time for the following doze, skip the missed doze and take only the following regularly scheduled doze. Do not take a double doze of this medication.

What happens if I overdose?

• Search abnormal medical attention if an overdose is suspected.

• Symptoms of a hydrocodone and phenylephrine overdose may include extreme drowsiness, dizziness, headache, seizures, dry mouth, cool and clammy skin, flushing, nausea, vomiting, difficult or decreased breathing, and unconsciousness.

What must I avoid while taking hydrocodone and phenylephrine?

• Use alcohol cautiously. Alcohol may magnify drowsiness and dizziness while taking hydrocodone and phenylephrine.

• Do not take another over-the-counter cough, cool, allergy, diet, pain, or sleep medications while taking hydrocodone and phenylephrine without first talking to your pharmacist or doctor. Another medications may also contain hydrocodone, phenylephrine, or another similar drugs, and you may accidentally take too many of these medicines.

What are the possible side effects of hydrocodone and phenylephrine?

• If you experience any of the next serious side effects, stop taking hydrocodone and phenylephrine and search abnormal medical attention or contact your doctor immediately:

· a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or person; or hives); or

· confusion, hallucinations, or unusual behavior.

• Another, smaller serious side effects may be more likely to occur. Continue to take hydrocodone and phenylephrine and conversation to your doctor if you experience

· dizziness, drowsiness, or sleepiness;

· restlessness or irritability;

· blurred vision;

· constipation;

· dry mouth;

· nausea, vomiting, or decreased appetite;

· muscle twitches;

· sweating;

· itching; or

· decreased urination.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect hydrocodone and phenylephrine?

• Hydrocodone and phenylephrine may magnify the effects of another drugs that reason drowsiness, including antidepressants, alcohol, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Speak your doctor about all medicines that you are taking, and do not take any medication unless your doctor approves.

• Drugs another than those listed here may also interact with hydrocodone and phenylephrine. Conversation to your doctor and pharmacist till taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist has more information about hydrocodone and phenylephrine written for health professionals that you may read.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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