AMINOPHYLLINE

(a min OFF i lin) Brand: Phyllocontin, Truphylline

What is the most significant information I must know about aminophylline?

• Do not crush or chew any extended-release formulation of aminophylline. Swallow the medicine intact. It is specially formulated to release slowly in your body. If you do not know whether your medicine is an extended-release formulation, ask your pharmacist.

• Call your doctor right away if you experience nausea, vomiting, insomnia, restlessness, seizures, heighten heart course, or a headache. These could be signs of too many aminophylline in your blood.

• Do not start or stop smoking without your doctor's knowledge. Smoking may affect your dosage.

• Do not take more of this medicine than is predesigned without consulting your doctor. Search medical attention if you are having increasing difficulty breathing.

What is aminophylline?

• Aminophylline is a bronchodilator. Aminophylline works in different ways: it relaxes muscles in your lungs and chest to let more air in, decreases the sensitivity of your lungs to allergens and another substances that reason inflammation, and increases the contractions of your diaphragm to draw more air into the lungs.

• Aminophylline is used to treat the symptoms of asthma, bronchitis, and emphysema.

• Aminophylline may also be used for purposes another than those listed in this medicine guide.

Who must not take aminophylline?

• Till taking this medicine, speak your doctor if you have

· a stomach ulcer;

· seizures or epilepsy;

· tall blood pressure, a heart condition, or any type of heart disease;

· fluid in your lungs;

· a thyroid condition;

· liver malady; or

· kidney disease.

• You may not be able to take aminophylline, or you may require a lower doze or particular monitoring during treatment if you have any of the conditions listed above.

• Aminophylline is in the FDA pregnancy category C. This means that it is not known whether aminophylline will harm an unborn child. Do not take this medicine without first talking to your doctor if you are pregnant.

• Aminophylline passes into breast milk and could affect a nursing child. Do not take aminophylline without first talking to your doctor if you are breast-feeding a baby.

• If you are over 60 years of age, you may be more likely to experience side effects from aminophylline. You may require a lower doze of this medication.

How must I take aminophylline?

• Take aminophylline exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

• Take every doze with a full glass of water.

• You can take aminophylline with food to lessen stomach upset.

• Take your doses at the same time each day to hold a constant level of aminophylline in your blood.

• Shake the liquid forms of this medicine well till use. To ensure that you get a correct doze, measure the liquid with a dose-measuring cup or spoon, not a regular tablespoon. If a spoon or cup is not provided with the medicine and you do not have one, ask your pharmacist where you can get one.

• Insert the suppositories rectally as directed.

• Do not switch to other brand or a generic form of aminophylline without the approval of your doctor.

• Store aminophylline at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. However, if it is nearly time for your following regularly scheduled doze, skip the missed doze and take the following one as directed. Do not take a double doze of this medication.

What happens if I overdose?

• Search abnormal medical attention.

• Symptoms of an aminophylline overdose include nausea, vomiting, headache, insomnia, tremor (shaking hands or twitching,), restlessness, seizures, and irregular heartbeats.

What must I avoid while taking aminophylline?

• Use caution when driving, operating machinery, or performing another hazardous activities. Aminophylline may reason dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

• Do not start or stop smoking without the approval of your doctor. Smoking changes the way your body uses aminophylline, and you may need a doze adjustment.

• Avoid changing your doze or changing the time of your daily doses.

• Do not change the brand, generic form, or formulation (tablet, capsule, liquid) of aminophylline that you are taking without the approval of your doctor. Various brands or formulations may require various dosages.

• Avoid eating overweening amounts of grilled or char-broiled foods. Doing so may also change the dosage of aminophylline that you need.

• Avoid caffeinated beverages such as coffee, tea, and cola. Aminophylline is related chemically to caffeine, and you may experience some side effects if you consume too many caffeine.

What are the possible side effects of aminophylline?

• If you experience any of the next serious side effects, stop taking aminophylline and search abnormal medical attention:

· an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or person; or hives);

· seizures;

· heighten or irregular heartbeats; or

· severe nausea or vomiting.

• Another, smaller serious side effects may also occur, although they are not general at appropriate doses. Continue to take aminophylline and conversation to your doctor if you experience

· slight nausea, decreased appetite, or weight loss;

· restlessness, tremor, or insomnia; or

· headache, lightheadedness, or dizziness.

• Side effects another than those listed here may also occur. Conversation to your doctor about any side effect that seems unusual or that is especially bothersome. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect aminophylline?

• Aminophylline interacts with much another drugs. Speak your doctor and pharmacist about all another medications that you are taking, including herbal remedies, vitamins, and another nonprescription items.

• The next drugs may magnify the levels of aminophylline in your blood, leading to dangerous side effects:

· alcohol;

· cimetidine (Tagamet, Tagamet HB);

· fluoroquinolone antibiotics such as enoxacin (Penetrex), lomefloxacin (Maxaquin), ciprofloxacin (Cipro), norfloxacin (Noroxin), and ofloxacin (Floxin);

· clarithromycin (Biaxin) and erythromycin (Ery-Tab, E.E.S., E-Mycin, others);

· disulfiram (Antabuse);

· estrogens (Ogen, Premarin, and much another types);

· fluvoxamine (Luvox);

· methotrexate (Folex, Rheumatrex);

· mexiletine (Mexitil) and propafenone (Rythmol);

· propranolol (Inderal);

· tacrine (Cognex);

· ticlopidine (Ticlid); and

· verapamil (Verelan, Calan, Isoptin).

• The next drugs may decrease aminophylline levels in your blood, leading to poor asthma control:

· aminoglutethimide (Cytadren),

· carbamazepine (Tegretol),

· isoproterenol (Isuprel),

· moricizine (Ethmozine),

· phenobarbital (Luminal, Solfoton),

· phenytoin (Dilantin),

· rifampin (Rifadin), and

· sucralfate (Carafate).

• Drugs another than those listed here may also interact with aminophylline or affect your condition. Conversation to your doctor and pharmacist till taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has additional information about aminophylline written for health professionals that you may read.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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