(AL oh GLIP tin and met FOR min) Brand: Kazano
You must not use this medicine if you have kidney malady, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
Alogliptin can reason pancreatitis. Stop using this medication and call your doctor at once if you have severe pain in your upper stomach spreading to your back, nausea and vomiting, and loss of appetite.
Some people develop lactic acidosis while taking metformin. Early symptoms may get worse over time and this condition can be fatal. Stop taking this medication and get abnormal medical help if you have even mild symptoms such as: muscle pain or weakness, trouble breathing, stomach pain, nausea, and feeling very weak or weary.
Alogliptin and metformin are oral diabetes medicines that help control blood sugar levels.
Metformin works by decreasing glucose (sugar) manufacture in the liver and decreasing absorption of glucose by the intestines. Alogliptin works by regulating the levels of insulin your body produces after eating.
Alogliptin and metformin is a combination medication used to treat type 2 diabetes. This medicine is not for treating type 1 diabetes.
Alogliptin and metformin may also be used for purposes not listed in this medicine guide.
You must not use this medicine if you are allergic to alogliptin or metformin, or if you have:
· kidney malady; or
· if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
Some people taking alogliptin and metformin develop a serious condition called lactic acidosis. This may be more likely if you have liver or kidney malady, congestive heart failure, a severe infection, if you are dehydrated, or if you drink big amounts of alcohol. Conversation with your doctor about your risk.
To create certain alogliptin and metformin is safety for you, speak your doctor if you have:
· liver disease;
· a history of pancreatitis;
· gallstones;
· a history of alcoholism; or
· if you are over 80 years old and have not recently had your kidney function checked.
If you need to have any type of x-ray or CT scan using a paint that is injected into your veins, you will need to temporarily stop taking alogliptin and metformin. Be certain your caregivers know onward of time that you are using this medicine.
Determined oral diabetes medications may magnify your risk of serious heart problems. However, not treating your diabetes can hurt your heart and another organs.
FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether alogliptin and metformin passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
Do not give this medicine to anyone under 18 years old without medical advice.
Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.
Take alogliptin and metformin with meals.
Your blood sugar will need to be checked often, and you may need another blood trials at your doctor's office.
Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, famine, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating.
Hold a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, heavy candy, crackers, raisins, and non-diet soda. Be certain your family and close friends know how to help you in an abnormal. If you have severe hypoglycemia and can't ate or drink, use a glucagon injection. Your doctor can prescribe a glucagon abnormal injection kit and speak you how to use it.
Also watch for signs of tall blood sugar (hyperglycemia) such as heighten thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.
Check your blood sugar carefully during times of stress, travel, diseases, surgery or medical abnormal, vigorous exercice, or if you drink alcohol or skip meals. These things can affect your glucose levels and your doze needs may also change. Do not change your medicine doze or schedule without your doctor's advice.
Alogliptin and metformin is only part of a treatment program that may also include diet, exercice, weight control, blood sugar testing, and particular medical care. Follow your doctor's instructions very closely.
Your doctor may have you take extra vitamin B12 while you are taking alogliptin and metformin. Take only the amount of vitamin B12 that your doctor has prescribed.
Store at room temperature away from moisture and heat.
Take the missed doze as soon as you remember (be certain to take the medication with food). Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
Avoid drinking alcohol. It lowers blood sugar and may magnify your risk of lactic acidosis.
Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
Some people develop lactic acidosis while taking alogliptin and metformin. Early symptoms may get worse over time and this condition can be fatal. Stop taking this medication and get abnormal medical help if you have even mild symptoms such as:
· muscle pain or weakness;
· numb or cool feeling in your arms and legs;
· trouble breathing;
· feeling dizzy, light-headed, weary, or very weak;
· stomach pain, nausea with vomiting; or
· slow or uneven heart rate.
Stop using alogliptin and call your doctor at once if you have:
· severe pain in your upper stomach spreading to your back;
· nausea and vomiting, loss of appetite, quick heart course;
· pain or burning when you urinate;
· itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
· heighten blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath);
· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.
General side effects may include:
· diarrhea;
· back pain, headache; or
· cool symptoms such as stuffy nose, sinus pain, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
Speak your doctor about all medicines you use, and those you start or stop using during your treatment with alogliptin and metformin, especially:
· cimetidine;
· morphine;
· quinine;
· ranitidine;
· topiramate;
· trimethoprim;
· vancomycin;
· zonisamide;
· acetazolamide, methazolamide, triamterene; or
· heart or blood pressure medication--amiloride, digoxin, procainamide, quinidine.
You may be more likely to have hyperglycemia (high blood sugar) if you take alogliptin and metformin with another drugs that can raise blood sugar, such as:
· isoniazid;
· a diuretic or "water pill";
· steroids (prednisone and others);
· phenothiazines (Compazine and others);
· thyroid medication (Synthroid and others);
· birth control pills and another hormones;
· seizure medicines (Dilantin and others);
· diet pills; and
· medicines to treat asthma, colds or allergies.
These lists are not complete. Another drugs may interact with alogliptin and metformin, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.
Your pharmacist can provide more information about alogliptin and metformin.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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