ACETAMINOPHEN, CAFFEINE, AND MAGNESIUM SALICYLATE

(ah seet oh MIN oh fen, KAF een, mag NEEZ ee um sa LIS il ate) Brand: KneeRelief

What is the most significant information I must know about this medicine?

• Do not give this medicine to a baby or teenager with a fever, flu symptoms, or chicken pox. Salicylates can reason Reye's syndrome, a serious and sometimes fatal condition in children.

• Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

• In rare cases, acetaminophen may reason a severe skin reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

What is acetaminophen, caffeine, and magnesium salicylate?

• Acetaminophen is a pain reliever and a fever reducer.

• Caffeine is used in this product to magnify the pain relieving effects of acetaminophen.

• Magnesium salicylate is used to reduce pain, inflammation, and fever.

• Acetaminophen, caffeine, and magnesium salicylate is a combination medication used to treat pain and swelling from conditions such as muscle aches, arthritis, and joint soreness.

• Acetaminophen, caffeine, and magnesium salicylate may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking this medicine?

• You must not use this medicine if you are allergic to acetaminophen, caffeine, or magnesium salicylate.

• Do not give this medicine to a baby or teenager with a fever, flu symptoms, or chicken pox. Salicylates can reason Reye's syndrome, a serious and sometimes fatal condition in children.

• To create certain this medication is safety for you, speak your doctor if you have:

· liver malady, cirrhosis, a history of alcoholism, or if you drink more than 3 alcoholic beverages for day;

· kidney disease;

· a stomach ulcer or bleeding; or

· an intestinal mess such as ulcerative colitis.

• FDA pregnancy category C. It is not known whether acetaminophen, caffeine, and magnesium salicylate will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• This medication can pass into breast milk and may harm a nursing child. Speak your doctor if you are breast-feeding a baby.

How must I take this medicine?

• Use this medicine exactly as directed on the label, or as it has been predesigned by your doctor. Do not take more of this medicine than is recommended. An overdose of acetaminophen can hurt your liver or reason death.

• Stop taking this medicine and call your doctor if you have a fever lasting longer than 3 days, or pain lasting longer than 10 days.

• Acetaminophen can reason unusual results with determined lab trials for glucose (sugar) in the urine. Speak any doctor who treats you that you are using acetaminophen, caffeine, and magnesium salicylate.

• If you need surgery, speak the surgeon onward of time that you are using this medication. You may need to stop using the medication for a short time.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Since this medication is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can hurt your liver or reason death.

• The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

• Overdose symptoms also may include ringing in your ears, confusion, agitation, hallucinations, or seizure (convulsions).

What must I avoid while taking this medicine?

• Avoid drinking alcohol. It may magnify your risk of liver hurt while taking acetaminophen.

• Ask a doctor or pharmacist till using any another pain, cool, allergy, or sleep medicine. Acetaminophen (sometimes abbreviated as APAP) is contained in much combination medicines. Taking determined commodity together can reason you to get too many acetaminophen which can lead to a fatal overdose. Check the label to see if a medication contains acetaminophen or APAP.

• Much medicines accessible over the counter also contain caffeine, salicylates, or similar medicines (such as aspirin, ibuprofen, ketoprofen, or naproxen). Ask your doctor till taking any another medicine for pain, arthritis, fever, or swelling.

What are the possible side effects of this medicine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• In rare cases, acetaminophen may reason a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medication and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you must never again take any medication that contains acetaminophen.

• Stop using this medication and call your doctor at once if you have:

· bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

· light bruising or bleeding; or

· swelling, rapid weight gain, few or no urinating.

• General side effects may include:

· upset stomach;

· trouble sleeping (insomnia); or

· feeling anxious or restless.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect this medicine?

• Ask a doctor or pharmacist if it is safety for you to use acetaminophen, caffeine, and magnesium salicylate if you are also using any of the next drugs:

· methotrexate;

· medicine used to prevent blood clots, such as fondaparinux; or

· aspirin or another NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve), ketorolac, and others.

• This list is not complete. Another drugs may interact with acetaminophen, caffeine, and magnesium salicylate, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen, caffeine, and magnesium salicylate.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.