(tre PROS ti nil) Brand: Remodulin
• Till using this medicine, speak your doctor if you have low blood pressure, liver malady, or a bleeding or blood clotting disorder.
• Treprostinil is given as an continuous (around-the-clock) injection using an infusion exhaust. The medication enters the body through a catheter placed under your skin or into a vein. Your doctor, nurse, or pharmacist will give you specific instructions on how to use an infusion exhaust and inject your medicine.
• Your doctor may want you to be in a hospital when you start using treprostinil. This is so you can be watched for any signs of serious side effects from the medicine.
• You will perhaps have to use this medication for different months or years to control your condition and hold it from getting worse.
• Use treprostinil regularly to get the most benefit. Get your prescription refilled till you run out of medication completely. Create certain you have a backup infusion exhaust and infusion sets accessible so as not to break your treatment if one infusion exhaust stops working.
• Call your doctor if your symptoms do not improve or if they get worse.
• Treprostinil dilates (or widens) the arteries and decreases the amount of blood clotting platelets in your body. These effects lower blood pressure in the pulmonary artery that leads from the heart to the lungs.
• Treprostinil is used to treat pulmonary arterial hypertension (PAH). It improves your capacity to exercice and prevents your condition from getting worse.
• Treprostinil may also be used for another purposes not listed in this medicine guide.
• If you have determined conditions, you may need a doze adjustment or particular trials to safely use this medication:
· low blood pressure;
· liver malady; or
· bleeding or blood clotting disorder.
• FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.
• It is not known whether treprostinil passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
• Use exactly as predesigned by your doctor. Do not use in larger or less amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results.
• Treprostinil is given as an continuous (around-the-clock) injection using an infusion exhaust. The medication enters the body through a catheter placed under your skin or into a vein. Your doctor, nurse, or pharmacist will give you specific instructions on how to use an infusion exhaust and inject your medication. Do not give yourself an injection if you do not understand these instructions. Call your doctor, nurse, or pharmacist for help with injection instructions.
• Your doctor may want you to be in a hospital when you start using treprostinil. This is so you can be watched for any signs of serious side effects from the medicine.
• You will perhaps have to use this medication for different months or years to control your condition and hold it from getting worse.
• Use treprostinil regularly to get the most benefit. Get your prescription refilled till you run out of medication completely. Create certain you have a backup infusion exhaust and infusion sets accessible so as not to break your treatment if one infusion exhaust stops working.
• Do not use the medicine if it has changed colors or has any particles in it. Call your doctor for a new prescription.
• Store unopened vials (bottles) of treprostinil at room temperature away from moisture and heat. After the medication has been placed into a syringe or exhaust, it must be given within 72 hours. If the medication has been diluted (mixed with a liquid), you should use the medication within 48 hours after mixing.
• Call your doctor if your symptoms do not improve or if they get worse.
• Call your doctor for instructions if you miss a doze of treprostinil.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose symptoms may include warmth and redness or tingling under your skin, headache, feeling light-headed, fainting, nausea, vomiting, diarrhea, or seizure (convulsions).
• Do not stop using treprostinil without first talking to your doctor. You may need to use smaller and smaller till you stop the medicine completely.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have any of these serious side effects:
· new or worsening PAH symptoms such as feeling short of breath (even with mild exertion), tiredness, chest pain, and pale skin;
· swelling in your hands or foots; or
· feeling like you might pass out.
• Smaller serious side effects may include:
· pain, swelling, redness, bleeding, or a heavy lump where your catheter is placed;
· dizziness;
· mild skin rash;
· headache or jaw pain;
· flushing (warmth, redness or tingling); or
· diarrhea or nausea.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all another medicines you use, especially:
· gemfibrozil (Lopid);
· a blood thinner such as warfarin (Coumadin);
· blood pressure medicine such as a diuretic (water pill); or
· medicine used to prevent blood clots, such as alteplase (Activase), cilostazol (Pletal), clopidogrel (Plavix), dipyridamole (Persantine), ticlopidine (Ticlid), and urokinase (Abbokinase).
• This list is not complete and another drugs may interact with treprostinil. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about treprostinil injection.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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