SITAGLIPTIN

(SI ta glip tin) Brand: Januvia

What is the most significant information I must know about sitagliptin?

• Do not use this medication if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

• Sitagliptin can reason pancreatitis. Stop using this medication and call your doctor at once if you have severe pain in your upper stomach spreading to your back, nausea and vomiting, and loss of appetite.

• Sitagliptin can reason a serious allergic reaction. Get abnormal medical help if you have a fever, sore throat, swelling or burning in your person, skin pain, and a skin rash that spreads and causes blistering and peeling.

What is sitagliptin?

• Sitagliptin is an oral diabetes medication that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating.

• Sitagliptin is for people with type 2 diabetes. Sitagliptin is sometimes used in combination with another diabetes medications, but is not for treating type 1 diabetes.

• Sitagliptin may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking sitagliptin?

• Do not use this medication if you are allergic to sitagliptin, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

• To create certain sitagliptin is safety for you, speak your doctor if you have:

· kidney malady (or if you are on dialysis); or

· a history of pancreatitis.

• FDA pregnancy category B. Sitagliptin is not expected to harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• Your name may need to be listed on a sitagliptin pregnancy registry when you start using this medicine.

• It is not known whether sitagliptin passes into breast milk or if it could harm a nursing child. Speak your doctor if you are breast-feeding a baby.

• Do not give this medicine to anyone under 18 years old without medical advice.

How must I take sitagliptin?

• Follow all directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results. Do not take this medication in larger or less amounts or for longer than recommended.

• You may take this medication with or without food. Follow your doctor's instructions.

• Your blood sugar will need to be checked often, and you may need another blood trials at your doctor's office. Visit your doctor regularly.

• Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, famine, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating.

• Hold a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, heavy candy, crackers, raisins, and non-diet soda. Be certain your family and close friends know how to help you in an abnormal. If you have severe hypoglycemia and can't ate or drink, use a glucagon injection. Your doctor can prescribe a glucagon abnormal injection kit and speak you how to use it.

• Also watch for signs of tall blood sugar (hyperglycemia) such as heighten thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

• Check your blood sugar carefully during times of stress, travel, diseases, surgery or medical abnormal, vigorous exercice, or if you drink alcohol or skip meals. These things can affect your glucose levels and your doze needs may also change. Do not change your medicine doze or schedule without your doctor's advice.

• Sitagliptin is only part of a complete program of treatment that also includes diet, exercice, weight control, and possibly another medications. It is significant to use this medication regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.

• Store sitagliptin at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

What must I avoid while taking sitagliptin?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of sitagliptin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using sitagliptin and call your doctor at once if you have:

· pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, quick heart course;

· few or no urinating;

· swelling, weight gain, feeling short of breath; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• General side effects may include:

· runny or stuffy nose, sore throat;

· headache, back pain, joint or muscle pain; or

· nausea, stomach pain, diarrhea, constipation.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect sitagliptin?

• Using determined medicines can create it harder for you to speak when you have low blood sugar. Speak your doctor if you use albuterol, clonidine, reserpine, or a beta-blocker (atenolol, metoprolol, propranolol, and others).

• Till you take sitagliptin, speak your doctor if you are also taking digoxin (Lanoxicaps, Lanoxin).

• Although sitagliptin is not as likely to reason hypoglycemia (low blood sugar) as some another oral diabetes medications, speak your doctor if you are taking any another drugs that can potentially lower blood sugar, such as:

· probenecid (Benemid);

· nonsteroidal anti-inflammatory drugs (NSAIDs);

· aspirin or another salicylates (including Pepto-Bismol);

· a blood thinner (warfarin, Coumadin);

· sulfa drugs (Bactrim, SMX-TMP, and others);

· a monoamine oxidase inhibitor (MAOI); or

· beta-blockers (Tenormin and others).

· insulin or another oral diabetes medications.

• This list is not complete. Another drugs may interact with sitagliptin, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.

Where can I get more information?

• Your pharmacist can provide more information about sitagliptin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.