(per TOO zoo mab) Brand: Perjeta
• Pertuzumab can reason birth defects or death to the unborn child. Do not use if you are pregnant.
• Till receiving pertuzumab, speak your doctor if you have heart malady, congestive heart failure, a history of heart onslaught, or any allergies or breathing problems. You may not be able to receive pertuzumab, or you may need a dosage adjustment or particular trials during treatment.
• Some people receiving a pertuzumab injection have had a reaction to the infusion (when the medication is injected into the vein). Speak your caregiver right away if you feel dizzy, nauseated, light-headed, weak, itchy, or short of breath during the injection.
• Pertuzumab is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
• Pertuzumab is used together with traztuzumab (Herceptin) and docetaxel (Docefrez, Taxotere) to treat breast cancer that has spread to another parts of the body.
• Pertuzumab is generally given after another cancer medications have been tried without successful treatment.
• Pertuzumab may also be used for another purposes not listed in this medicine guide.
• You must not use pertuzumab if you are allergic to it, or if you are pregnant or breast-feeding.
• To create certain you can safely receive pertuzumab, speak your doctor if you have any of these another conditions:
· a heart rhythm disorder;
· congestive heart failure;
· untreated or uncontrolled tall blood pressure (hypertension);
· if you have recently had a heart attack;
· if you have received a cancer medicine such as doxorubicin (Adriamycin, Doxil), daunorubicin (Cerubidine, Daunoxome), epirubicin (Ellence), idarubicin (Idamycin), or valrubicin (Valstar); or
· if you have ever had a radiation treatment in your chest area.
• FDA pregnancy category D. Do not use pertuzumab if you are pregnant. It can reason birth defects or death to the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment. Use effective birth control while you are using this medicine and for at least 6 months after your treatment ends.
• If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to estimate any effects of pertuzumab on the baby.
• It is not known whether pertuzumab passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are using pertuzumab.
• Pertuzumab is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Pertuzumab should be given slowly, and the IV infusion can take 30 to 60 minutes to complete.
• Till you receive this medicine, you may need to undergo a biopsy to create certain pertuzumab is the right medicine to treat your cancer.
• To be certain this medicine is not causing deleterious effects, your blood will need to be tested on a regular basis. Your heart function may also need to be tested. Do not miss any scheduled visits to your doctor.
• To create certain this medicine is helping your condition and not causing deleterious effects, your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these trials. Do not miss any follow-up visits to your doctor.
• Pertuzumab is generally given once each 3 weeks. Follow your doctor's instructions.
• Call your doctor for instructions if you miss an appointment for your pertuzumab injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Follow your doctor's instructions about any restrictions on food, beverages, or activity.
• Some people receiving a pertuzumab injection have had a reaction to the infusion (when the medication is injected into the vein). Speak your caregiver right away if you feel weak, weary, or nauseated, or if you have a quick heartbeat, headache, fever, chills, muscle pain, or an unusual taste in your mouth during the injection.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have a serious side effect such as:
· fever, chills, body aches, flu symptoms;
· white patches or sores internal your mouth or on your lips;
· feeling short of breath, even with mild exertion;
· swelling, rapid weight gain; or
· anxiety, sweating, pale skin, severe shortness of breath, wheezing, gasping for breath, cough with foamy mucus, chest pain, quick or uneven heart rate.
• Smaller serious side effects are more likely to occur, such as:
· nausea, diarrhea;
· weary feeling;
· dry skin, temporary hair loss;
· mild rash or itching;
· numbness or tingling in your hands or foots; or
· cool symptoms such as stuffy nose, sneezing, sore throat.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• There may be another drugs that can affect pertuzumab. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about pertuzumab.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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