CHLORPROPAMIDE

(klor PROE pa mide) Brand: Diabinese

What is the most significant information I must know about chlorpropamide?

• Do not use this medicine if you are allergic to chlorpropamide, or if you are in a state of diabetic ketoacidosis. Call your doctor for treatment with insulin.

• Till taking chlorpropamide, speak your doctor if you have kidney or liver malady, a mess of your pituitary or adrenal glands, a history of heart malady, or if you are malnourished.

• Determined oral diabetes medications may magnify your risk of serious heart problems. However, not treating your diabetes can hurt your heart and another organs. Conversation to your doctor about the risks and benefits of treating your diabetes with chlorpropamide.

• Low blood sugar (hypoglycemia) can occur if you skip a meal, exercice too long, drink alcohol, or are under stress. Symptoms include headache, famine, weakness, sweating, tremors, irritability, or trouble concentrating. Carry heavy candy or glucose tablets with you in case you have low blood sugar. Another sugar sources include orange juice and milk. Be certain your family and close friends know how to help you in an emergency.

• Signs of blood sugar that is too tall (hyperglycemia) may include heighten thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss. Your blood sugar will need to be checked often, and you may need to adjust your chlorpropamide doze.

• Chlorpropamide is only part of a complete program of treatment that may also include diet, exercice, weight control, foot care, eye care, and testing your blood sugar. Follow your diet, medicine, and exercice routines very closely. Changing any of these factors can affect your blood sugar levels.

What is chlorpropamide?

• Chlorpropamide is an oral diabetes medication that helps control blood sugar levels. This medicine helps your pancreas manufacture insulin.

• Chlorpropamide is used together with diet and exercice to treat type 2 diabetes. Another diabetes medicines are sometimes used in combination with chlorpropamide if needed.

• Chlorpropamide must not be used by itself to treat type 1 diabetes.

• Chlorpropamide may also be used for purposes not listed in this medicine guide.

What must I discuss with my doctor till taking chlorpropamide?

• Do not use this medicine if you are allergic to chlorpropamide, or if you are in a state of diabetic ketoacidosis. Call your doctor for treatment with insulin.

• To create certain you can safely take chlorpropamide, speak your doctor if you have any of these another conditions:

· liver disease;

· kidney disease;

· a mess of your pituitary or adrenal glands;

· a history of heart malady; or

· if you are malnourished.

• FDA pregnancy category C. It is not known whether chlorpropamide will harm an unborn child. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medicine around the time of delivery. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• Chlorpropamide can pass into breast milk and may harm a nursing child. You must not breast-feed while you are taking chlorpropamide.

How must I take chlorpropamide?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Chlorpropamide is generally taken once for day with breakfast. Follow your doctor's instructions.

• Your blood sugar will need to be checked often, and you may need another blood trials at your doctor's office. Visit your doctor regularly.

• Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, famine, weakness, sweating, tremors, irritability, or trouble concentrating.

• Always hold a source of sugar accessible in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and can't ate or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon abnormal injection kit and speak you how to give the injection. Be certain your family and close friends know how to help you in an emergency.

• Also watch for signs of blood sugar that is too tall (hyperglycemia). These symptoms include heighten thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

• Check your blood sugar carefully during a time of stress or diseases, if you travel, exercice more than normal, drink alcohol, or skip meals. These things can affect your glucose levels and your doze needs may also change.

• Ask your doctor how to adjust your chlorpropamide doze if needed. Do not change your medicine doze or schedule without your doctor's advice.

• Chlorpropamide is only part of a complete program of treatment that may also include diet, exercice, weight control, and testing your blood sugar. Follow your diet, medicine, and exercice routines very closely. Changing any of these factors can affect your blood sugar levels.

• Use chlorpropamide regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.

• Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

• Take the missed doze as soon as you remember (take the medicine with food if your doctor instructs you to). Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. A chlorpropamide overdose can reason life-threatening hypoglycemia.

• Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

What must I avoid while taking chlorpropamide?

• Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.

• Avoid exposure to sunlight or tanning beds. Chlorpropamide can create you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What are the possible side effects of chlorpropamide?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Hypoglycemia, or low blood sugar, is the most general side effect of chlorpropamide. Symptoms include headache, famine, weakness, sweating, tremors, irritability, trouble concentrating, rapid breathing, quick heartbeat, fainting, or seizure (severe hypoglycemia can be fatal). Carry heavy candy or glucose tablets with you in case you have low blood sugar.

• Stop taking chlorpropamide and call your doctor at once if you have a serious side effect such as:

· light bruising or bleeding, unusual weakness;

· pale skin, fever, confusion;

· trouble concentrating, memory problems, feeling unsteady, hallucinations;

· feeling light-headed, fainting;

· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· throbbing headache, sweating, severe nausea, trouble breathing, quick or pounding heartbeats, blurred vision, spinning sensation; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· mild nausea, vomiting, diarrhea;

· mild famine; or

· mild skin rash, redness, or itching.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect chlorpropamide?

• You may be more likely to have hyperglycemia (high blood sugar) if you are taking chlorpropamide with another drugs that raise blood sugar, such as:

· isoniazid;

· diuretics (water pills);

· steroids (prednisone and others);

· phenothiazines (Compazine and others);

· thyroid medication (Synthroid and others);

· birth control pills and another hormones;

· seizure medicines (Dilantin and others);

· diet pills; and

· medicines to treat asthma, colds or allergies.

• You may be more likely to have hypoglycemia (low blood sugar) if you are taking chlorpropamide with another drugs that lower blood sugar, such as:

· exenatide (Byetta);

· probenecid (Benemid);

· some nonsteroidal anti-inflammatory drugs (NSAIDs);

· aspirin or another salicylates (including Pepto-Bismol);

· sulfa drugs (Bactrim and others);

· a monoamine oxidase inhibitor (MAOI);

· beta-blockers (Tenormin and others);

· a blood thinner (warfarin, Coumadin, Jantoven); and

· another oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

• This list is not complete and another drugs may interact with chlorpropamide. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about chlorpropamide.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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