TIOTROPIUM INHALATION

(tye oh TROE pee um) Brand: Spiriva

What is the most significant information I must know about tiotropium inhalation?

• A tiotropium capsule is for use only in the HandiHaler device. Do not take the capsule by mouth. Use only one capsule at a time.

• Till using this medicine, speak your doctor if you have narrow-angle glaucoma, or an enlarged prostate or bladder obstruction.

• Tiotropium inhalation is used to prevent bronchospasm attacks. Do not use this medicine to treat a bronchospasm onslaught that has already begun. It will not work quick satis to reverse your symptoms. Use only a fast-acting inhalation medicine to treat an onslaught.

• Use this medicine exactly as it was predesigned for you. Do not use it in larger doses or for longer than recommended by your doctor.

• Conversation with your doctor if any of your medications do not seem to work as well in treating or preventing bronchospasm attacks.

What is tiotropium inhalation?

• Tiotropium inhalation is used to prevent bronchospasm (narrowing of the airways in the lungs) in people with bronchitis, emphysema, or COPD (chronic obstructive pulmonary disease).

• Tiotropium inhalation may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till using tiotropium inhalation?

• You must not use this medicine if you are allergic to tiotropium or ipratropium (Atrovent, Combivent, DuoNeb).

• To create certain you can safely take tiotropium inhalation, speak your doctor if you have any of these another conditions:

· narrow-angle glaucoma;

· kidney disease;

· enlarged prostate or urination problems; or

· if you are allergic to milk.

• FDA pregnancy category C. It is not known whether tiotropium inhalation is deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known if tiotropium passes into breast milk or if it could harm a nursing child. Do not use tiotropium inhalation without telling your doctor if you are breast-feeding a baby.

How must I use tiotropium inhalation?

• Use exactly as predesigned by your doctor. Do not use in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• This medicine comes with patient instructions for safety and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

• The tiotropium capsule is for use only in the HandiHaler device. Do not take the capsule by mouth. Use only one capsule at a time.

• Use tiotropium inhalation regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.

• Conversation with your doctor if any of your medications do not seem to work as well in treating or preventing attacks.

• To be certain this medicine is helping your condition, your lung function will need to be tested on a regular basis. Visit your doctor regularly.

• Hold every tiotropium capsule in its blister pack before you are ready to seat the capsule into the HandiHaler and use the device. Throw away any capsule that is not used right after you have taken it out of the blister pack. Exposure to air can ruin the capsule.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Use the medicine as soon as you remember. If it is nearly time for the following doze, skip the missed doze and wait before your following regularly scheduled doze. Do not use extra medication to create up the missed dose.

• Do not use the Spiriva Handihaler more than 1 time in a 24-hour period.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include dry mouth, eye redness, constipation, stomach pain, and confusion or drowsiness.

What must I avoid while using tiotropium inhalation?

• Avoid getting this medicine in your eyes. If this does happen, rinse with water.

What are the possible side effects of tiotropium inhalation?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· wheezing, chest pain or tightness, trouble breathing;

· pain or burning when you urinate;

· blurred vision, eye pain or redness, seeing halos near lights;

· rapid heart rate;

· sores or white patches of your mouth, lips, or tongue; or

· urinating smaller than normal or not at all.

• Smaller serious side effects may include:

· dry mouth;

· constipation, upset stomach, vomiting;

· cool symptoms such as stuffy nose, sneezing, sore throat;

· nosebleed; or

· muscle pain.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect tiotropium inhalation?

• Speak your doctor about all another medicines you use, especially:

· atropine (Atreza, Sal-Tropine);

· belladonna (Donnatal, and others)

· benztropine (Cogentin);

· dimenhydrinate (Dramamine);

· methscopolamine (Pamine);

· scopolamine (Transderm-Scop);

· theophylline (Elixophyllin, Theo-24, Theochron, Uniphyl), and others;

· tiotropium (Spiriva);

· bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

· cough, cool, or allergy medicine;

· irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

· steroid medicine such as prednisone (Deltasone, Sterapred), methylprednisolone (Medrol), fluticasone (Advair , Flonase, Flovent, Veramyst), beclomethasone (Qvar), budesonide (Pulmicort, Rhinocort, Symbicort), dexamethasone (Cortastat, Dexasone, Solurex, DexPak), mometasone (Asmanex, Nasonex), triamcinolone (Nasacort), and others; or

· ulcer medications such as glycopyrrolate (Robinul) or mepenzolate (Cantil).

• This list is not complete and another drugs may interact with tiotropium inhalation. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about tiotropium inhalation.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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