ORLISTAT

(OR li stat) Brand: alli, Xenical

What is the most significant information I must know about orlistat?

• Do not take orlistat if you are pregnant. Weight loss is not recommended during pregnancy, even if you are overweight or obese.

• You must not take this medicine if you are allergic to orlistat, if you are pregnant, or if you have gallbladder problems or chronic malabsorption syndrome (an inability to absorb food and nutrients properly).

• Till taking orlistat, speak your doctor if you have an underactive thyroid, a history of gallstones or pancreatitis, type 1 or type 2 diabetes, an eating mess, liver or kidney malady, or if you take another weight-loss medications (prescription or over-the-counter).

• Do not give over-the-counter orlistat (alli) to a baby younger than 18 years old. Prescription orlistat (Xenical) must not be used by anyone age 12 to 18 without the advice of a doctor.

• Orlistat should be used only by the face for whom it was prescribed. Never share orlistat with other face, especially somebody who has a history of eating mess. Hold the medicine in a seat where others can't get to it.

• Orlistat is only part of a complete program of treatment that also includes diet, exercice, and weight control. Your daily intake of thick, protein, and carbohydrates must be evenly divided over all of your daily meals. Follow your diet, medicine, and exercice routines very closely.

• Avoid a diet that is tall in thick. High-fat meals taken in combination with orlistat can magnify your risk of unpleasant side effects on your stomach or intestines.

What is orlistat?

• Orlistat blocks some of the thick that you ate, keeping it from being absorbed by your body.

• Orlistat is used together with a reduced-calorie diet and weight maintenance to treat obesity in people with determined risk factors (such as diabetes, tall blood pressure, and tall cholesterol or triglycerides).

• Orlistat may also be used for purposes not listed in this medicine guide.

• It is dangerous to purchase orlistat on the Internet or from vendors external of the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Samples of "alli" purchased on the Internet have been found to contain sibutramine (Meridia), a prescription weight loss medicine that can have dangerous side effects in determined people. For more information, contact the U.S. Food and Drug Administration (FDA) or visit www.fda.gov/buyonlineguide.

What must I discuss with my healthcare provider till taking orlistat?

• You must not take orlistat if you are allergic to it, or if you have:

· gallbladder problems;

· chronic malabsorption syndrome (an inability to absorb food and nutrients properly); or

· if you are pregnant.

• To create certain you can safely take orlistat, speak your doctor if you have any of these another conditions:

· an underactive thyroid;

· a history of gallstones or kidney stones;

· a history of pancreatitis;

· liver disease;

· kidney disease;

· type 1 or type 2 diabetes;

· an eating mess (anorexia or bulimia); or

· if you take any another weight-loss medications (prescription or over-the-counter).

• FDA pregnancy category X. Do not use orlistat if you are pregnant. Weight loss is not recommended during pregnancy, even if you are overweight or obese. Stop taking orlistat and speak your doctor right away if you become pregnant.

• Taking orlistat can create it harder for your body to absorb determined vitamins. These vitamins are significant if you are nursing a child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Do not give over-the-counter orlistat (alli) to a baby younger than 18 years old. Prescription orlistat (Xenical) must not be used by anyone age 12 to 18 without the advice of a doctor.

How must I take orlistat?

• Take exactly as directed on the label, or as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended.

• This medicine comes with patient instructions for safety and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

• Take orlistat during or within 1 hour after a meal that contains some thick (no more than 30% of the calories for that meal). Orlistat is generally taken 3 times daily.

• If you skip a meal or you ate a meal that does not contain any thick, skip your orlistat doze for that meal.

• The thick content of your daily diet must not be greater than 30% of your total daily caloric intake. For example, if you ate 1200 calories for day, no more than 360 of those calories must be in the form of fat.

• Read the label of all food items you consume, paying particular attention to the number of servings for container. Your doctor, nutrition counselor, or dietitian can help you develop a healthy eating plan.

• Your doctor may recommend you take vitamin and mineral supplements while you are taking orlistat. This medicine can create it harder for your body to absorb fat-soluble vitamins, such as vitamins A, D, E, and K. Follow your doctor's instructions about the type of multi-vitamin or mineral supplement to use.

• Take your vitamin or supplement at bedtime, or at least 2 hours till or after you take orlistat.

• Store at room temperature away from moisture and heat. Hold the bottle tightly closed. Throw away any unused orlistat after the expiration date on the medication label has passed.

• Hold track of the amount of medication used from every new bottle. Orlistat is a drug that may be misused as a weight-loss help, and you must be aware if anyone is using your medication improperly or without a prescription.

What happens if I miss a dose?

• Take the missed doze as soon as you remember, but no more than 1 hour after eating a meal. If it has been more than an hour since your recent meal, skip the missed doze and take the medication at your following regularly scheduled time. Do not take extra medication to create up the missed dose.

• If you miss a meal, or if you have a meal without thick, you can skip your doze of orlistat for that meal also.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking orlistat?

• Avoid a diet that is tall in thick. High-fat meals taken in combination with orlistat can magnify your risk of unpleasant side effects on your stomach or intestines.

What are the possible side effects of orlistat?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using orlistat and call your doctor at once if you have a serious side effect such as:

· severe pain in your lower back, blood in your urine;

· urinating smaller than normal or not at all;

· drowsiness, confusion, mood changes, heighten thirst;

· swelling, weight gain, feeling short of breath;

· severe pain in your upper stomach spreading to your back, nausea and vomiting, quick heart course; or

· nausea, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

• The next side effects occur commonly with the use of orlistat. They are the natural effects of orlistat's fat-blocking action and are actually signs that the medicine is working properly. These side effects are generally temporary and may lessen as you continue treatment with orlistat:

· oily spotting in your undergarments;

· oily or fatty stools;

· orange or brown colored oil in your stool;

· gas with discharge, an oily discharge;

· loose stools, or an urgent need to go to the bathroom, inability to control bowel movements;

· an heighten number of bowel movements;

· stomach pain, nausea, vomiting, diarrhea, rectal pain; or

· weakness, dark urine, clay-colored stools, itching, loss of appetite, or jaundice (yellowing of the skin or eyes).

• Another side effects that may occur while taking orlistat include:

· problems with your teeth or gums;

· cool symptoms such as stuffy nose, sneezing, cough;

· fever, chills, sore throat, flu symptoms;

· headache, back pain; or

· mild skin rash.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect orlistat?

• Speak your doctor about all another medications you use, especially:

· cyclosporine (Gengraf, Neoral, Sandimmune);

· a vitamin or mineral supplement that contains beta carotene or vitamin E;

· levothyroxine (Synthroid, Levoxyl, Levothroid);

· insulin or diabetes medications you take by mouth;

· digoxin (digitalis, Lanoxin, Lanoxicaps); or

· a blood thinner such as warfarin (Coumadin, Jantoven).

• This list is not complete and another drugs may interact with orlistat. Speak your doctor about all medications you use. This includes prescription, over the counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about orlistat.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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