(GOE se REL in) Brand: Zoladex
• Goserelin can harm an unborn child or reason birth defects. Unless you are being treated for advanced breast cancer, you must not use goserelin during pregnancy. Use effective non-hormonal (barrier) birth control during treatment and for at least 12 weeks after treatment ends. Speak your doctor right away if you become pregnant during treatment.
• You must not breast-feed while you are using goserelin.
• You must not use this medicine if you are allergic to goserelin or to similar hormone medications such as leuprolide (Lupron, Eligard, Viadur), nafarelin (Synarel), or ganirelix (Antagon).
• Till you receive goserelin, speak your doctor if you have osteoporosis, diabetes, urination problems, a condition affecting your spine, a history of heart onslaught or stroke, risk factors for coronary artery malady (such as tall blood pressure, tall cholesterol, smoking, or being overweight), or if you have emergency bleeding that your doctor has not checked.
• Goserelin can decrease bone mineral density, which may magnify your risk of developing osteoporosis. This risk may be greater if you smoke, drink alcohol frequently, have a family history of osteoporosis, or use determined drugs such as seizure medications or steroids. Conversation to your doctor about your individual risk of bone loss.
• Call your doctor at once if you have a serious side effect such as severe numbness or tingling in your legs or foots, muscle weakness, problems with balance or coordination, loss of bladder or bowel control, urinating smaller than normal, pain or burning when you urinate, blood in your urine or stools, light bruising, heighten thirst or urination, fruity breath odor, trouble breathing, sudden numbness or weakness, sudden severe headache, confusion, problems with vision or speech, or chest pain spreading to the hand or shoulder.
• Goserelin is a man-made form of a hormone that regulates much processes in the body. Goserelin overstimulates the body's own manufacture of determined hormones, which causes that manufacture to shut down temporarily.
• Goserelin is used in men to treat symptoms of prostate cancer, and in women to treat breast cancer or endometriosis. Goserelin is also used in women to prepare the lining of the uterus for endometrial ablation (a surgery to correct emergency uterine bleeding).
• If you are receiving goserelin to treat prostate cancer, use any another medications your doctor has predesigned to excellent treat your condition. Goserelin treats only the symptoms of prostate cancer but does not treat the cancer itself.
• Goserelin may also be used for another purposes not listed in this medicine guide.
• You must not receive this medicine if you are allergic to goserelin or to similar hormone medications such as leuprolide (Lupron, Eligard, Viadur), nafarelin (Synarel), or ganirelix (Antagon). Do not use goserelin if you are pregnant or breast-feeding.
• To create certain you can safely use goserelin, speak your doctor if you have any of these another conditions:
· osteoporosis or low bone density;
· diabetes;
· a history of heart onslaught or stroke;
· risk factors for coronary artery malady (such as tall blood pressure, tall cholesterol, smoking, or being overweight);
· urination problems;
· a condition affecting your spine; or
· if you have emergency bleeding that your doctor has not checked.
• FDA pregnancy category X. This medicine can harm an unborn child or reason birth defects. However, goserelin is sometimes given to pregnant women being treated for advanced breast cancer. Unless you are being treated for advanced breast cancer, you must not use goserelin during pregnancy.
• Till receiving goserelin, you may need a pregnancy test to create certain you are not pregnant. Speak your doctor right away if you become pregnant during treatment. Use effective birth control while you are using this medicine and for at least 12 weeks after your treatment ends.
• If you are a premenopausal woman, goserelin must reason your periods to stop during treatment. However, you should still use an effective barrier form of birth control (such as a condom or diaphragm with spermicide gel or inserts). Hormonal forms of contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective during your treatment with goserelin.
• After you stop using goserelin, you must begin having regular periods again. Call your doctor if your usual periods do not return within 12 weeks after your goserelin treatment ends.
• It is not known whether goserelin passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are using goserelin.
• Goserelin can decrease bone mineral density, which may magnify your risk of developing osteoporosis. This risk may be greater if you smoke, drink alcohol frequently, have a family history of osteoporosis, or use determined drugs such as seizure medications or steroids. Conversation to your doctor about your individual risk of bone loss.
• Goserelin is given in a tiny implant that is inserted through a needle injected under the skin of your upper stomach. You will receive this injection in a clinic or doctor's office.
• You are not likely to be able to feel the implant through your skin, and it must not reason pain or discomfort. The implant will dissolve in your body over time.
• A new goserelin implant is generally injected each 28 days, but the timing of your doze may be various if you are also receiving chemotherapy. Follow your doctor's instructions. It is very significant to receive your goserelin injections on time every month.
• If you are a premenopausal woman, you must stop having menstrual periods during treatment with goserelin. Call your doctor if you still have regular periods. Missing a doze can reason breakthrough bleeding.
• While your hormone levels are adjusting to goserelin, you may announcement heighten symptoms or new symptoms of your condition. This must be only temporary during the first little weeks of treatment. Speak your doctor if your symptoms do not improve after different weeks of using goserelin.
• Your blood sugar may need to be checked while using goserelin, even if you are not diabetic. You may need another blood trials at your doctor's office. Visit your doctor regularly.
• This medicine can reason you to have unusual results with determined medical trials. Speak any doctor who treats you that you are using goserelin.
• Call your doctor for instructions if you miss an appointment for your goserelin injection.
• Since the goserelin implant contains a specific amount of the medicine, you are not likely to receive an overdose.
• Avoid drinking alcohol. It can magnify your risk of bone loss while you are being treated with goserelin.
• Avoid smoking, which can magnify your risk of bone loss, stroke, or heart problems.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have a serious side effect such as:
· back pain, severe numbness or tingling in your legs or feet;
· muscle weakness, problems with balance or coordination;
· loss of bladder or bowel control;
· urinating smaller than normal or not at all;
· pain or burning when you urinate;
· blood in your urine or stools;
· feeling like you might pass out;
· trouble breathing;
· pale skin, light bruising;
· nausea, loss of appetite, heighten thirst, muscle weakness, confusion, and feeling weary or restless;
· tall blood sugar (increased thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss);
· sudden numbness or weakness, sudden severe headache, confusion, problems with vision or speech; or
· chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling.
• Smaller serious side effects may include:
· hot flashes, sweating, headache, dizziness;
· mood changes, heighten or decreased interest in sex;
· vaginal dryness, itching, or discharge;
· impotence, fewer erections than normal;
· breast swelling or tenderness;
· bone pain;
· diarrhea, constipation;
· sleep problems (insomnia); or
· acne, mild skin rash or itching.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• There may be another drugs that can interact with goserelin. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about goserelin.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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