DEXTRAN, TALL MOLECULAR WEIGHT

(DEX tran) Brand: Dextran 70 6% in 0.9% Sodium Chloride, Dextran 70 6% in 5% Dextrose, Gentran 70, Hyskon

What is the most significant information I must know about high-molecular weight dextran?

• You must not be given this medicine if you are allergic to dextran, or if you have severe kidney or heart disease.

• If possible till you receive dextran, speak your doctor if you have a bleeding or blood clotting mess, a blood cell mess, heart malady or congestive heart failure, kidney malady, a stomach or intestinal mess, pulmonary edema (fluid in the lungs), urination problems, a food or drug allergy, or if you are on a low-salt diet.

• In an abnormal situation, it may not be possible till you are treated to speak your caregivers about any health conditions you have or if you are pregnant or breast-feeding. However, create certain any doctor caring for you afterward knows that you have received this medication.

• Speak your doctor about all another medications you use, especially a blood thinner, steroid medicine, digoxin, or a diuretic.

What is high-molecular weight dextran?

• High-molecular weight dextran is a plasma volume expander derived from natural sources of sugar (glucose). It works by restoring blood plasma lost through severe bleeding.

• Severe blood loss can decrease oxygen levels, which can lead to organ failure, brain hurt, coma, and possibly death. Plasma is needed to circulate red blood cells that deliver oxygen throughout the body.

• Dextran is used to treat hypovolemia (a decrease in the volume of circulating blood plasma), that can result from severe blood loss after surgery, injury, or another causes of bleeding.

• Dextran is also used to expand the internal of the uterus, making it easier for a doctor to see with a scope during a diagnostic procedure called hysteroscopy.

• Dextran may also be used for another purposes not listed in this medicine guide.

What must I discuss with my health care provider till I receive high-molecular weight dextran?

• You must not be given this medicine if you are allergic to dextran, or if you have severe kidney or heart disease.

• If you have determined conditions, you may need a doze adjustment or particular trials to safely receive this medicine. If possible till you receive dextran, speak your doctor if you have:

· a bleeding or blood clotting disorder;

· a blood cell mess such as thrombocytopenia (lack of platelets);

· heart malady or congestive heart failure;

· kidney disease;

· a stomach or intestinal disorder;

· pulmonary edema (fluid in the lungs);

· urination problems not caused by hypovolemia;

· a food or drug allergy; or

· if you are on a low-salt diet.

• FDA pregnancy category C. It is not known whether dextran is deleterious to an unborn child. If possible till you receive this medicine, speak your doctor if you are pregnant.

• It is not known whether dextran passes into breast milk or if it could harm a nursing child. Speak your doctor if you are breast-feeding a baby.

• In an abnormal situation, it may not be possible till you are treated to speak your caregivers about any health conditions you have or if you are pregnant or breast-feeding. However, create certain any doctor caring for you afterward knows that you have received this medication.

How is high-molecular weight dextran given?

• Dextran is given as an injection through a needle placed into a vein. For a hysteroscopy procedure, dextran is placed into the uterus using a little tube.

• You will receive this injection in a clinic or hospital setting. A doctor, nurse, or another healthcare professional will give you this medication.

• Your breathing, blood pressure, oxygen levels, and another vital signs will be watched closely while you are receiving this medication.

• To be certain dextran is helping your condition, your blood may need to be tested often. This will help your doctor determine how long to treat you with dextran.

What happens if I miss a dose?

• Since dextran is given as needed by a healthcare professional, it is not likely that you will miss a dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have received too many of this medicine.

• An overdose of dextran is not expected to manufacture life-threatening symptoms.

What must I avoid after receiving high-molecular weight dextran?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity after you are treated with dextran.

What are the possible side effects of high-molecular weight dextran?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Speak your caregivers at once if you have a serious side effect such as:

· wheezing or tight feeling in your chest;

· urinating smaller than normal or not at all;

· swelling in your hands or feet;

· unusual bleeding, or any bleeding that will not stop;

· feeling like you might pass out; or

· burning, itching, swelling, or pain near the IV needle.

• Smaller serious side effects may include:

· nausea, vomiting, stomach pain;

· joint pain;

· stuffy nose;

· mild itching; or

· skin rash.

• This is not a complete list of side effects and others may occur. Speak your doctor about any unusual or bothersome side effect. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect high-molecular weight dextran?

• Till you receive dextran, speak your doctor if you are also using:

· a blood thinner such as warfarin (Coumadin);

· steroids (prednisolone and others);

· digoxin (digitalis, Lanoxin); or

· a diuretic (water pill) such as amiloride (Midamor, Moduretic), spironolactone (Aldactone, Aldactazide), or triamterene (Dyrenium, Dyazide, Maxzide).

• This list is not complete and there may be another drugs that can interact with dextran. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about dextran.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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