(BEN da MUS teen) Brand: Treanda
• Bendamustine is used to treat chronic lymphocytic leukemia, or indolent B-cell non-Hodgkin lymphoma.
• Till you receive bendamustine, speak your doctor if you have a weak immune system, fever or another signs of infection, a metabolic mess or electrolyte imbalance, liver or kidney malady, or if you smoke.
• Speak your caregiver right away if you have a fever, chills, itching, or skin rash during or shortly after the injection.
• Bendamustine can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).
• Bendamustine is a cancer medicine that interferes with the growth of cancer cells and slows their growth and spread in the body.
• Bendamustine is used to treat chronic lymphocytic leukemia. Bendamustine is also used to treat indolent B-cell non-Hodgkin lymphoma after another medications have been tried without successful treatment of this condition.
• Bendamustine may also be used for purposes not listed in this medicine guide.
• You must not receive this medicine if you are allergic to bendamustine or mannitol (Osmitrol).
• To create certain bendamustine is safety for you, speak your doctor if you have:
· a weak immune system;
· fever or another signs of infection;
· a metabolic mess or electrolyte imbalance;
· liver disease;
· kidney malady; or
· if you smoke.
• FDA pregnancy category D. Do not receive bendamustine if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.
• It is not known whether bendamustine passes into breast milk or if it could harm a nursing child. Speak your doctor if you are breast-feeding a baby.
• Some people receiving bendamustine have developed determined types of cancers. It is not known whether this medicine causes cancer. Conversation with your doctor about the risks and benefits of using bendamustine.
• Bendamustine is injected into a vein through an IV. A healthcare provider will give you this injection.
• Bendamustine is generally given for 2 days in a row each 21 to 28 days. You may receive up to 8 treatments total, depending on the condition being treated. Follow your doctor's instructions.
• You may be given another medications to help prevent determined side effects of bendamustine.
• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when the medication is injected.
• Bendamustine can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.
• Call your doctor for instructions if you miss an appointment for your bendamustine injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Bendamustine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Some people receiving a bendamustine injection have had a reaction to the infusion (when the medication is injected into the vein). Speak your caregiver right away if you have fever, chills, itching, or skin rash during or shortly after the injection.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Speak your caregivers at once if you have:
· fever, chills, body aches, flu symptoms, sores in your mouth and throat;
· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;
· light bruising or bleeding, purple or red pinpoint spots under your skin, unusual weakness;
· cool symptoms such as stuffy nose, sneezing, cough, sore throat;
· lower back pain, blood in your urine, urinating smaller than normal or not at all;
· numbness or tingly feeling near your mouth;
· muscle weakness, tightness, or contraction, overactive reflexes;
· quick or slow heart course, weak pulse, confusion;
· dry mouth, feeling very thirsty or hot, hard sweating or hot and dry skin;
· severe blistering, peeling, and red skin rash; or
· pain, swelling, redness, skin changes, or signs of infection where the medication was injected.
• General side effects may include:
· mild nausea, vomiting, diarrhea, constipation, or upset stomach;
· swelling in your hands or feet;
· headache, dizziness, drowsiness;
· loss of appetite, weight loss; or
· mild skin rash.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with bendamustine, especially:
· allopurinol;
· cimetidine;
· fluvoxamine;
· omeprazole;
· thiabendazole; or
· a barbiturate--butabarbital, secobarbital, phenobarbital, and others.
• This list is not complete. Another drugs may interact with bendamustine, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.
• Your doctor or pharmacist can provide more information about bendamustine.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.