THIABENDAZOLE

(thye a BEN da zole) Brand: Mintezol

What is the most significant information I must know about thiabendazole?

• Take thiabendazole with food to lessen stomach upset. Chew the chewable tablets thoroughly till swallowing.

• Follow your doctor's instructions regarding treatment; washing of clothes, linens, and towels; and household disinfecting. Pinworm infections are easily spread from one face to another.

• Use caution when driving, operating machinery, or performing another hazardous activities. Thiabendazole may reason dizziness. If you experience dizziness, avoid these activities.

What is thiabendazole?

• Thiabendazole is an "antihelmintic," or anti-worm, medicine. It prevents worms from growing or multiplying in the body.

• Thiabendazole is used to treat infections caused by worms such as threadworm. Thiabendazole may also be used to treat pinworm (when it occurs with threadworm), hookworm, whipworm, roundworm, and trichinosis.

• Thiabendazole may also be used for purposes another than those listed in this medicine guide.

What must I discuss with my healthcare provider till taking thiabendazole?

• Till taking thiabendazole, speak your doctor about any another medical conditions that you have, especially liver or kidney malady. You may not be able to take thiabendazole, or you may require a dosage adjustment or particular monitoring during treatment if you have any another medical conditions.

• Thiabendazole is in the FDA pregnancy category C. This means that it is not known whether it will be deleterious to an unborn child. Do not take thiabendazole without first talking to your doctor if you are pregnant.

• It is also not known whether thiabendazole passes into breast milk. Do not take thiabendazole without first talking to your doctor if you are breast-feeding a baby.

• Children who weigh smaller than 30 pounds must not use thiabendazole unless otherwise directed by a doctor.

How must I take thiabendazole?

• Take thiabendazole exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

• Take every doze with a full glass of water.

• Chew the chewable tablets thoroughly till swallowing.

• Shake the suspension well till measuring a doze. Measure every doze with a dose-measuring dropper, spoon or cup, not a regular table spoon, to ensure that you measure the correct amount of medication. Ask your pharmacist where you can get a dose-measuring device if you do not have one.

• Take every doze with food to lessen stomach upset.

• Doses are generally taken twice a day. Follow your doctor's instructions.

• It may take 2 days or more for the treatment to remove the worm from the stomach and intestines. Repeat treatment is generally necessary in 7 days to prevent reinfection.

• Fasting, laxatives, or purging will not help to cure the infection.

• Treatment of family members and another close contacts may be necessary. Pinworm is spread very easily to others in close contact with the infected person.

• To prevent reinfection, toilets should be disinfected daily, and clothing, linens, towels, and pajamas should be changed and washed daily.

• Store thiabendazole at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. However, if it is nearly time for the following doze, skip the doze you missed and take only the following regularly scheduled doze. Do not take a double doze of this medication.

What happens if I overdose?

• Search abnormal medical attention.

• Symptoms of a thiabendazole overdose might include changes in vision and changes in behavior or personality.

What must I avoid while taking thiabendazole?

• Treatment of family members and another close contacts may be necessary. Pinworm is spread very easily to others in close contact with the infected person.

• Toilets should be disinfected daily and clothing, linens, towels, and pajamas should be changed and washed daily to prevent reinfection.

• Use caution when driving, operating machinery, or performing another hazardous activities. Thiabendazole may reason dizziness. If you experience dizziness, avoid these activities.

What are the possible side effects of thiabendazole?

• Stop taking thiabendazole and search abnormal medical attention if you experience an allergic reaction (swelling of the lips, tongue, or person; shortness of breath; closing of the throat; or hives).

• Rarely, another serious side effects can occur. Stop taking thiabendazole and contact your doctor if you experience

· seizures;

· behavior or personality changes;

· skin rash;

· vision changes; or

· yellowing of the skin or eyes.

• Another, smaller serious side effects may be more likely to occur. Continue to take thiabendazole and conversation to your doctor if you experience

· dizziness, drowsiness, or headache;

· numbness;

· nausea, vomiting, diarrhea, upset stomach, or decreased appetite;

· unusual urine odor;

· fever or chills;

· ringing in the ears;

· blurred vision or dryness of the eyes; or

· appearance of live worms in the mouth or nose.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect thiabendazole?

• Theophylline (Theo-Dur, Theolair, Theochron, Theo-Bid, Elixophyllin, others) may have dangerous side effects when taken with thiabendazole. Your doctor may want to monitor blood theophylline levels if you are taking theophylline during treatment with thiabendazole.

• Drugs another than those listed here may also interact with thiabendazole. Conversation to your doctor and pharmacist till taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

• Your pharmacist can provide more information about thiabendazole.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.