SOMATROPIN

(soe ma TROE pin) Brand: Genotropin, Genotropin Miniquick, Humatrope, Norditropin, Norditropin Cartridge, Norditropin FlexPro Pen, Norditropin Nordiflex Pen, Nutropin, Nutropin AQ, Omnitrope, Saizen, Serostim, Tev-tropin, Zorbtive

What is the most significant information I must know about somatropin?

• Till you receive somatropin, speak your doctor about all your past and gift medical conditions, especially allergies, trauma, surgery, diabetes, cancer, breathing problems, liver or kidney malady, scoliosis, tall blood pressure, pancreas mess, underactive thyroid, or a brain tumor.

• Also speak your doctor about all another medications you use, especially steroids or diabetes medications. Your dosages of these medicines may need to be changed when you start using somatropin. Do not stop using a steroid suddenly or change any of your medicine doses without your doctor's advice.

• If you have Prader-Willi syndrome and are using somatropin, call your doctor promptly if you develop signs of lung or breathing problems such as shortness of breath, coughing, or new or heighten snoring.

• Call your doctor at once if you have sudden and severe pain in your upper stomach with nausea and vomiting, quick heartbeat, heighten thirst or urination, weight loss, or vision changes and sudden, severe pain behind your eyes.

What is somatropin?

Somatropin is a form of human growth hormone. Human growth hormone is significant in the body for the growth of bones and muscles.

Somatropin is used to treat growth failure in children and adults who lack natural growth hormone, and in those with chronic kidney failure, Noonan syndrome, Turner syndrome, Prader-Willi syndrome, short stature at birth with no catch-up growth, and another causes. Somatropin is also used to prevent severe weight loss in people with AIDS, or to treat short bowel syndrome.

Somatropin may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till using somatropin?

• Till you receive somatropin, speak your doctor if you have ever had an allergic reaction to a growth hormone medication, or to drug preservatives such as benzyl alcohol, metacresol or glycerin.

• You must not use this medicine if you are allergic to somatropin, or if you have:

· diabetic retinopathy (a serious eye condition caused by diabetes);

· cancer; or

· Prader-Willi syndrome and are also overweight or have sleep apnea or severe respiratory (lung) problems.

• You must also not use somatropin if you have a serious medical condition after having:

· open heart surgery or stomach surgery;

· trauma or another medical abnormal; or

· breathing problems (such as lung failure).

• To create certain you can safely take somatropin, speak your doctor if you have any of these another conditions:

· liver disease;

· kidney malady (or if you are on dialysis);

· diabetes;

· a pituitary gland disorder;

· scoliosis;

· tall blood pressure (hypertension);

· a pancreas mess (especially in children);

· a history of cancer;

· carpal tunnel syndrome;

· underactive thyroid; or

· a brain tumor or lesion.

• FDA pregnancy category B. Some brands of somatropin are not expected to harm an unborn child, including Genotropin, Omnitrope, Saizen, Serostim, and Zorbtive.

• FDA pregnancy category C. It is not known whether determined another brands of somatropin will harm an unborn child, including Humatrope, Norditropin, Nutropin, and Tev-tropin.

• Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• It is not known whether somatropin passes into breast milk or if it could harm a nursing child. Do not use somatropin without telling your doctor if you are breast-feeding a baby.

How must I use somatropin?

• Use exactly as predesigned by your doctor. Do not use in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Your doze and brand of somatropin, and how often you give it will depend on what you are being treated for. Follow the directions on your prescription label.

Somatropin is injected into a muscle or under the skin. You may be shown how to use injections at house. Do not self-inject this medication if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

• Use a various seat on your body every time you give the injection. Your care provider will show you the excellent places on your body to inject the medicine. Do not inject into the same seat two times in a row. Do not inject this medication into skin or muscle that is red, sore, infected, or injured.

• Do not shake the medicine bottle or you may ruin the medication. When mixing somatropin with a diluent (liquid), use a gentle swirling motion. Do not use the medicine if it has changed colors or has particles in it. Call your doctor for a new prescription.

• Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Hold this container out of the reach of children and pets.

• To be certain this medicine is helping your condition and not causing harm, your blood and growth progress will need to be tested often. Your eyes may also need to be checked. Visit your doctor regularly.

• If you are being treated for short bowel syndrome, follow the diet plan created for you by your doctor or nutrition counselor to help control your condition. Somatropin is not a cure for short bowel syndrome.

• If you use a form of somatropin that comes in a cartridge for use with an injection pen, use only the pen injection system provided with the somatropin brand you use.

How you store this medication will depend on what brand you are using and what diluent you are mixing somatropin with. After mixing somatropin, you may need to use it right away or you may be able to store it for later use. Read and carefully follow the instructions provided with your medication about proper storage of somatropin till and after it has been mixed. Ask your pharmacist if you have any questions about proper storage of your medication.

• Throw away any somatropin left over after the expiration date on the label has passed.

What happens if I miss a dose?

• Use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.

• Call your doctor if you miss more than 3 doses in a row.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose can reason tremors or shaking, cool sweats, heighten famine, headache, drowsiness, weakness, dizziness, quick heartbeat, and nausea. Long-term overdose may reason overweening growth.

What must I avoid while using somatropin?

• If you use Zorbtive to treat short bowel syndrome, avoid drinking fruit juices or soda beverages. Follow the instructions of your doctor or nutrition counselor about what types of liquids you must drink while using Zorbtive.

• Avoid drinking alcohol if you have short bowel syndrome. Alcohol can irritate your stomach and could create your condition worse.

What are the possible side effects of somatropin?

• If you have Prader-Willi syndrome, call your doctor promptly if you develop signs of lung or breathing problems such as shortness of breath, coughing, or new or heighten snoring. Rare cases of serious breathing problems have occurred in patients with Prader-Willi syndrome who use somatropin.

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have any of these serious side effects:

· severe pain in your upper stomach spreading to your back, nausea and vomiting, quick heart rate;

· heighten thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss;

· sudden and severe pain behind your eyes, vision changes;

· swelling in your head, person, hands, or foots; or

· numbness or tingling in your wrist, arm, or fingers.

• Smaller serious side effects may include:

· headache, feeling tired;

· redness, soreness, swelling, rash, itching, pain, or bruising where the medication was injected;

· pain in your arms or legs, joint stiffness or pain;

· muscle pain; or

· cool symptoms such as stuffy nose, sneezing, sore throat.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect somatropin?

• Till using somatropin, speak your doctor if you use insulin or take oral (by mouth) medication to treat diabetes. Somatropin may affect blood sugar levels and you may need to adjust your doze of the diabetes medicine. Do not change the doze of your diabetes medicine without your doctor's advice.

• Speak your doctor if you use any type of steroid medication such as cortisone, dexamethasone, methylprednisolone, prednisone, and others. Steroids can create somatropin smaller effective and your doses may need to be adjusted. Do not stop using a steroid suddenly. Follow your doctor's instructions.

• Speak your doctor about all another medications you use, especially cyclosporine (Gengraf, Neoral, Sandimmune), seizure medicine, birth control pills, anabolic steroids, or hormone replacement medications for men or women.

• This list is not complete and another drugs may interact with somatropin. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about somatropin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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