SAXAGLIPTIN

(SAX a GLIP tin) Brand: Onglyza

What is the most significant information I must know about saxagliptin?

• You must not use this medicine if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

• Saxagliptin is not for treating type 1 diabetes.

What is saxagliptin?

• Saxagliptin is an oral diabetes medication that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating.

• Saxagliptin is for people with type 2 diabetes. Saxagliptin is sometimes used in combination with another diabetes medications, but is not for treating type 1 diabetes.

• Saxagliptin may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking saxagliptin?

• You must not use this medicine if you have ever had a severe allergic reaction to saxagliptin, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

• To create certain you can safely take saxagliptin, speak your doctor if you have:

· kidney malady (or if you are on dialysis);

· pancreatitis;

· gallstones;

· tall triglycerides (a type of thick in the blood); or

· a history of alcoholism.

• FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether saxagliptin passes into breast milk or if it could harm a nursing child. Speak your doctor if you are breast-feeding a baby.

• Saxagliptin must not be given to a baby younger than 18 years old without a doctor's advice.

How must I take saxagliptin?

• Follow all directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results. Do not take this medication in larger or less amounts or for longer than recommended.

• You may take this medication with or without food. Follow your doctor's instructions.

• Do not crush, chew, or interrupt a saxagliptin tablet. Swallow it intact.

• Your blood sugar will need to be checked often, and you may need another blood trials at your doctor's office.

• Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, famine, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating. Always hold a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, heavy candy, crackers, raisins, and non-diet soda. Be certain your family and close friends know how to help you in an emergency.

• If you have severe hypoglycemia and can't ate or drink, use a glucagon injection. Your doctor can prescribe a glucagon abnormal injection kit and speak you how to use it.

• Check your blood sugar carefully during times of stress, travel, diseases, surgery or medical abnormal, vigorous exercice, or if you drink alcohol or skip meals. These things can affect your glucose levels and your doze needs may also change. Do not change your medicine doze or schedule without your doctor's advice.

• Your doctor may want you to stop taking saxagliptin for a short time if you become ill, have a fever or infection, or if you have surgery or a medical abnormal.

• Saxagliptin is only part of a complete program of treatment that also includes diet, exercice, weight control, and possibly another medications. It is significant to use this medication regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.

• Store at room temperature away from moisture and heat

What happens if I miss a dose?

• Take the missed doze as soon as you remember (be certain to take the medication with food if your doctor has instructed you to). Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, confusion, tremors, sweating, quick heart course, trouble speaking, nausea, vomiting, rapid breathing, fainting, and seizure (convulsions).

What must I avoid while taking saxagliptin?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of saxagliptin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives, a purple or red skin rash that spreads and causes blistering and peeling; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have:

· severe pain in your upper stomach spreading to your back, nausea and vomiting, quick heart rate;

· pain or burning when you urinate;

· swelling in your hands, ankles, or foots; or

· light bruising or bleeding.

• General side effects may include:

· runny or stuffy nose, sore throat, cough; or

· headache.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect saxagliptin?

• Other drugs may magnify or decrease the effects of saxagliptin on lowering your blood sugar. Speak your doctor about all medications you use. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.

Where can I get more information?

• Your pharmacist can provide more information about saxagliptin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.