Pentobarbital (Nembutal) (C-II); Barbiturate; Cap: 50, 100 mg
Elix: 20 mg/5 mL
Inj: 50 mg/mL
Supp: 30, 60, 120, 200 mg
Sedation (PR):
2-12 mos: 30 mg
1-4 yrs: 30-60 mg
5-12 yrs: 60 mg
>12yrs: 60-120 mg
Pre-op sedation: 2-6 mg/kg PO/IM x 1 (max 100 mg) or 1-3 mg/kg
IV x 1
Pentobarbital coma: loading dose 10-15 mg/kg
IV over 1-2 hours followed by 2-3 mg/kg/hr continuous
IV infusion
Therapeutic
serum levels for
pentobarbital coma: 20-40 mcg/mL