(peg ah SPAR jase) Brand: Oncaspar
• You must not use pegaspargase if you are allergic to it, or if you have ever received asparaginase and it caused pancreatitis, severe bleeding, a blood clot, or a severe allergic reaction.
• Pegaspargase can interfere with blood cells that help your blood to clot. Call your doctor if you have unusual bruising or bleeding, or if you have sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, or problems with vision or balance.
• Pegaspargase is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
• Pegaspargase is used in combination with another cancer medications to treat acute lymphoblastic leukemia. This medication is also used to treat allergic reactions to other cancer medicine called asparaginase (Elspar).
• Pegaspargase may also be used for purposes another than those listed in this medicine guide.
• You must not use pegaspargase if you are allergic to it, or if you have ever received asparaginase and it caused any of the next conditions:
· a blood clot;
· pancreatitis;
· severe bleeding; or
· a severe allergic reaction.
• To create certain pegaspargase is safety for you, speak your doctor if you have:
· a pancreas disorder;
· diabetes;
· bleeding or blood clotting mess such as hemophilia;
· any allergies; or
· a history of stroke or blood clot.
• FDA pregnancy category C. It is not known whether pegaspargase will harm an unborn child. Speak your doctor if you are pregnant. Use effective birth control to avoid pregnancy during your treatment with pegaspargase. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.
• It is not known whether pegaspargase passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.
• Pegaspargase is injected into a muscle or into a vein through an IV. A healthcare provider will give you this injection.
• You will be watched closely for at least 1 hour after receiving pegaspargase, to create certain you do not have an allergic reaction to the medication.
• Pegaspargase can lower blood cells that help your blood to clot. Your blood will need to be tested often to be certain this medicine is not causing deleterious effects.
• Contact your doctor if you miss an appointment for your pegaspargase injection.
• Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
• Avoid activities that may magnify your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have:
· sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
· severe pain in your upper stomach spreading to your back, nausea and vomiting, quick heart rate;
· dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
· tall blood sugar (increased thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss).
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Another drugs may interact with pegaspargase, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.
• Your doctor or pharmacist can provide more information about pegaspargase.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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