(as PAR a jin ase ESH er EEK ee a KOE lye) Brand: Elspar
• Asparaginase is a cancer medicine used to treat acute lymphocytic lymphoma.
• You must not receive this medication if you have ever used asparaginase and it caused severe bleeding, allergic reaction, pancreatitis, or blood clot.
• Asparaginase can magnify your risk of blood clot or stroke. Call your doctor at once if you have sudden numbness or weakness (especially on one side of the body), slurred speech, chest pain, pain or swelling in your leg, or if you cough up blood.
• You may also develop liver or pancreas problems. Call your doctor at once if you have loss of appetite, nausea and vomiting, severe pain in your upper stomach spreading to your back, dark urine, or jaundice (yellowing of the skin or eyes).
• Asparaginase can reason a severe allergic reaction, even if you have received it without reaction in the past. Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Asparaginase is a cancer medicine that interferes with the growth of cancer cells and slows their growth and spread in the body.
• Asparaginase is used to treat acute lymphocytic lymphoma.
• Asparaginase may also be used for purposes not listed in this medicine guide.
• You must not receive this medication if you have ever used asparaginase and it caused severe bleeding, allergic reaction, pancreatitis, or blood clot.
• To create certain asparaginase is safety for you, speak your doctor if you have:
· liver disease;
· diabetes (asparaginase can raise blood sugar);
· a bleeding or blood-clotting disorder;
· history of stroke; or
· history of pancreatitis.
• FDA pregnancy category C. It is not known whether asparaginase will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• It is not known whether asparaginase passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.
• Asparaginase is injected into a muscle, or into a vein through an IV. A healthcare provider will give you this injection.
• This medication is generally given three times for week.
• While using asparaginase, you may need frequent blood trials at your doctor's office.
• Contact your doctor if you miss an appointment for your asparaginase injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Asparaginase is highly toxic and both the powder and solution should be handled with care. Avoid inhaling vapors from the medication, or allowing the medication to come into contact with your skin, eyes, nose, or mouth. If the medication gets on your skin, wash the area right away with soap and water. If the medication gets into your eyes, rinse them for at least 15 minutes with water, saline, or another irrigating solution and search abnormal medical attention.
• Avoid being around people who are sick or have infections. Speak your doctor at once if you develop signs of infection.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling with or without pain in your arms and legs; swelling of your person, lips, tongue, or throat.
• Even if you have received asparaginase without reaction in the past, you may have an allergic reaction to the medicine when you receive it again.
• Call your doctor at once if you have:
· severe pain in your upper stomach spreading to your back, nausea and vomiting, quick heart rate;
· light bruising or bleeding, unusual weakness;
· sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
· chest pain, sudden cough, wheezing, rapid breathing, coughing up blood;
· pain, swelling, warmth, or redness in one or both legs;
· headache, confusion, change in mental status, vision loss, seizure (convulsions); or
· dark urine, jaundice (yellowing of the skin or eyes).
• General side effects may include:
· heighten thirst and urination.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Another drugs may interact with asparaginase, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.
• Your doctor or pharmacist can provide more information about asparaginase.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.