NEVIRAPINE (VIRAMUNE, NVP)

Nevirapine (Viramune, NVP); Antiretroviral, Non-nucleoside Reverse Transcriptase Inhibitor; Susp: 10 mg/ml
Tab, scored: 200 mg
>3 mos-12 yrs: 120 mg/m2/dose qd x 14 days, then increase to 120-200 mg/m2/dose q12h if no rash or other adverse reactions occur (max 200
mg/dose) >12 yrs: initially 200 mg PO qd x 14 days, then increase to 200 mg PO bid
Severe life-threatening hepatotoxicity has been reported. Rash, fever, headache. Rash is less common when patients are started with a lower initial
dose and then escalated up to usual maintenance dose. If rash develops, do not use prednisone as it may increase the incidence and severity of the
rash. May take with or without food.
(21)
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