REVERSE TRANSCRIPTASE

This enzyme of the HIV virus (and other retroviruses) converts the single-stranded viral RNA into DNA, the form in which the cell carries its genes. The antiviral drugs approved in the US for the treatment of HIV infection-AZT, ddC and ddI-all work by interfering with this stage of the viral life cycle. See also AZT; ddC; ddI; DNA; Ribonucleic Acid.
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