MITOTANE

(MYE toe tane) Brand: Lysodren

What is the most significant information I must know about mitotane?

• You may receive your first little doses of mitotane in a hospital setting where you can be monitored in case the medicine causes serious side effects.

• You must not use this medicine if you are allergic to mitotane.

• Till taking mitotane, speak your doctor if you have liver malady, or if you have had a last infection, surgery, or trauma.

• Always wear rubber gloves when handling mitotane tablets. The medication from a crushed or broken tablet can be dangerous if it gets on your skin.

• You may need to take steroid medicine along with mitotane to excellent treat your condition. Be certain to read the medicine manual or patient instructions provided with every of your medications. Do not change your doses or medicine schedule without advice from your doctor.

• If you have any type of infection, serious injury or medical abnormal, you may need to stop taking this medicine for a short time. Your doctor will determine when you can start taking mitotane again.

• Carry an ID card or wear a medical alert bracelet stating that you are taking mitotane, in case of an abnormal. Any doctor, dentist, or abnormal medical care provider who treats you must know that you are using mitotane.

• You should stay under the care of a doctor while taking mitotane. Do not miss any scheduled appointments.

• It may take up to different months of using mitotane till your symptoms improve. Conversation with your doctor if your symptoms do not improve or if they get worse.

What is mitotane?

• Mitotane is a cancer medicine. That interferes with the growth of cancer cells and slows their growth and spread in the body.

• Mitotane is used to treat cancer of the adrenal gland (adrenal cortical carcinoma).

• Mitotane may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking mitotane?

• You must not use this medicine if you are allergic to mitotane.

• If you have any of these another conditions, you may need a doze adjustment or particular trials to safely use this medication:

· last infection, surgery, or trauma;

· liver disease.

• FDA pregnancy category C. It is not known whether mitotane is deleterious to an unborn child. Till taking this medicine, speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether mitotane passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take mitotane?

• You may receive your first little doses of mitotane in a hospital setting where you can be monitored in case the medicine causes serious side effects.

• Take mitotane exactly as predesigned by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

• You may take mitotane with or without food.

• Always wear rubber gloves when handling mitotane tablets. Do not crush or interrupt a tablet, or use a tablet that has been accidentally broken. The medication from a crushed or broken tablet can be dangerous if it gets on your skin. If skin contact occurs, wash the area with soap and water. Ask your doctor or pharmacist how to safely dispose of the broken tablet.

• Your doctor may occasionally change your doze to create certain you get the excellent results from this medicine. You may also need to take steroid medicine to excellent treat your condition. Be certain to read the medicine manual or patient instructions provided with every of your medications. Do not change your doses or medicine schedule without advice from your doctor.

• Contact your doctor at once if you develop signs of infection such as fever, chills, sore throat, flu symptoms, loss of appetite, nausea and vomiting, mouth sores, or unusual weakness.

• To be certain this medicine is helping your condition and is not causing deleterious effects, your doctor will need to check your progress on a regular basis. You should stay under the care of a doctor while taking mitotane. Do not miss any scheduled appointments.

• It may take up to different months of using mitotane till your symptoms improve. For excellent results, hold using your medications as directed. Conversation with your doctor if your symptoms do not improve or if they get worse.

• Store mitotane at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. If it is nearly time for your following doze, wait before then to take the medication and skip the missed doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Symptoms of a mitotane overdose are not known.

What must I avoid while taking mitotane?

• Avoid being around people who have colds, the flu, or another contagious illnesses. Contact your doctor at once if you develop signs of infection.

• Avoid activities that may magnify your risk of trauma or injury.

• Mitotane can reason side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.

• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.

What are the possible side effects of mitotane?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· feeling like you might pass out;

· quick or pounding heartbeats;

· warmth, redness, or tingly feeling under your skin;

· sweating, cool or clammy skin;

· tall fever, chills, uncontrolled shaking;

· blurred or double vision;

· confusion, problems with speech, balance, or walking;

· pain or burning when you urinate;

· blood in your urine; or

· unexpected weight loss.

• Smaller serious side effects may include:

· dizziness, spinning sensation;

· drowsiness, weary feeling;

· depressed mood;

· mild skin rash;

· nausea, vomiting, diarrhea; or

· loss of appetite.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect mitotane?

• Till using mitotane, speak your doctor if you regularly use another medicines that create you sleepy (such as cool or allergy medication, sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression, or anxiety). They can add to sleepiness caused by mitotane.

• Speak your doctor about all another medications you use, especially:

· a blood thinner such as warfarin;

· spironolactone.

• This list is not complete and there may be another drugs that can interact with mitotane. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about mitotane.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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