MIDODRINE

(MY doe drin) Brand: ProAmatine

What is the most significant information I must know about midodrine?

• In some cases, midodrine may reason an overweening magnify in blood pressure, especially when lying down. Contact your doctor immediately or search abnormal medical attention if you experience an unusual awareness of heartbeats, pounding in the ears, headache, or blurred vision. These may be signs of heighten blood pressure.

• In some cases, heighten blood pressure may reason a slowed heart course. Contact your doctor immediately or search abnormal medical attention if you experience decreased pulse course, heighten dizziness, fainting, or an unusual awareness of heartbeats. These may be signs of a slowed heart rate.

• Midodrine can reason heighten blood pressure when lying down. The recent doze of midodrine must be taken at least 3 to 4 hours till bedtime. If you are going to be lying down for any length of time during the day, you may need to skip a doze of midodrine. Conversation to your doctor about how to take midodrine if you lie down during the day.

• Another prescription and over-the-counter medicines may reason an magnify in blood pressure, which may be dangerous when taken with midodrine. Do not take any another prescription or over-the-counter medicines or herbal commodity especially cough, cool, or allergy commodity, weight loss commodity, asthma or respiratory medicines, migraine headache medicines, heart or blood pressure medicines, or antidepressants without first talking to your doctor.

What is midodrine?

• Midodrine is a vasopressor. Midodrine causes constriction (tightening) of the blood vessels which leads to an magnify in blood pressure.

• Midodrine is used to treat low blood pressure.

• Midodrine may also be used for purposes another than those listed here.

What must I discuss with my healthcare provider till taking midodrine?

• Do not take midodrine without first talking to your doctor if you have

· heart or blood vessel problems (other than low blood pressure);

· tall blood pressure;

· kidney problems;

· difficulty urinating;

· pheochromocytoma; or

· over active thyroid.

• Till taking this medicine, speak your doctor if you have

· liver problems;

· visual disturbances;

· diabetes; or

· glaucoma.

• You may not be able to take midodrine, or you may require a dosage adjustment or particular monitoring during treatment.

• Midodrine is in the FDA pregnancy category C. This means that it is not known whether it will be deleterious to an unborn child. Do not take midodrine without first talking to your doctor if you are pregnant or could become pregnant during treatment.

• It is not known whether midodrine passes into breast milk. Do not take midodrine without first talking to your doctor if you are breast-feeding a baby.

How must I take midodrine?

• Take midodrine exactly as directed by your doctor. If you do not understand these instructions, ask your doctor, nurse, or pharmacist to explain them to you.

• Take every doze with a full glass of water.

• Midodrine can be taken with or without food.

• Take midodrine at regular intervals as directed by your doctor.

• Your doctor may want you to have regular blood pressure monitoring or another medical evaluations during treatment with midodrine to monitor progress and side effects.

• Store midodrine at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember then wait the predesigned amount of time till taking other doze. Usually, doses must not be taken smaller than 3 hours separately. Follow your doctor's instructions. Do not take a double doze of this medicine, unless otherwise directed by your doctor.

What happens if I overdose?

• Search abnormal medical attention if an overdose is suspected.

• Symptoms of a midodrine overdose may include heighten blood pressure (flushing, headache, pounding heartbeat, blurred vision), goosebumps, difficulty urination, a feeling of being cool, and loss of consciousness.

What must I avoid while taking midodrine?

What are the possible side effects of midodrine?

• If you experience any of the next serious side effects, stop taking midodrine and search abnormal medical attention or contact your doctor immediately:

· an allergic reaction (shortness of breath; closing of the throat; hives; swelling of the lips, person, or tongue; rash; or fainting); or

· irregular heartbeats, fluttering feeling in the chest, or chest pain.

• Another, smaller serious side effects may be more likely to occur. Continue to take midodrine and conversation to your doctor if you experience

· chills or goosebumps;

· itching or tingling of the skin;

· heighten need to urinate or difficulty with urination;

· feeling of pressure or fullness in the head;

· dryness of the mouth; or

· nervousness or anxiety.

• Side effects another than those listed here may also occur. Conversation to your doctor about any side effect that seems unusual or that is especially bothersome. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect midodrine?

• Till taking midodrine, conversation to your doctor if you are taking any another medicines especially any of the following:

· an alpha adrenergic blocker such as alfuzosin (Uroxatral), doxazosin (Cardura), guanadrel (Hylorel), prazosin (Minipress), or terazosin (Hytrin);

· flecainide (Tambocor);

· cimetidine (Tagamet, Tagamet HB) or ranitidine (Zantac, Zantac 75);

· digoxin (Lanoxin);

· metformin (Glucophage);

· fludrocortisone (Florinef);

· triamterene (Dyrenium, Dyazide, Maxzide);

· drugs that stimulate alpha-adrenergic receptors such as pseudoephedrine, phenylephrine, ephedrine, or dihydroergotamine;

· quinidine (Quinaglute, Quinidex, Quin-Release); or

· procainamide (Procan SR, Procanbid, Pronestyl).

• You may not be able to take midodrine, or you may require a dosage adjustment or particular monitoring during treatment if you are taking any of the medicines listed above.

• Another prescription and over-the-counter medicines may reason an magnify in blood pressure, which may be dangerous when taken with midodrine. Do not take any another prescription or over-the-counter medicines or herbal commodity especially cough, cool, or allergy commodity, weight loss commodity, asthma or respiratory medicines, migraine headache medicines, heart or blood pressure medicines, irregular heartbeat medicines, or antidepressants without first talking to your doctor.

• Drugs another than those listed here may also interact with midodrine. Conversation to your doctor and pharmacist till taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist has additional information about midodrine written for health professionals that you may read.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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